Exercise in Improving Health and Quality of Life in Breast Cancer Survivors
Invasive Breast Carcinoma
About this trial
This is an interventional supportive care trial for Invasive Breast Carcinoma
Eligibility Criteria
Inclusion Criteria:
- Understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure
- Have a previous history of invasive breast cancer who have completed treatment except for hormonal therapy and zoledronic acid (Zometa)
- Do not meet the United States (U.S.) Center for Disease Control and Prevention's physical activity guidelines (150 minutes or 2 hours and 30 minutes a week of moderate-intensity exercise)
- Meets criteria for participation in low to moderate risk exercise based on the American College of Sports Medicine guideline (ACSM)
Exclusion Criteria:
- Have uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
- Are pregnant or nursing
- Are unwilling or unable to follow protocol requirements
- Have any condition which in the investigator's opinion deems the subject an unsuitable candidate to participate in this study
- Have metastatic breast cancer
- Have orthopedic or neuromuscular disorders or arthritis that preclude participation in exercise
Sites / Locations
- Roswell Park Cancer Institute
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Experimental
Experimental
Experimental
Active Comparator
Active Comparator
Arm I (home-based walking program, resistance training)
Arm II (home-based Zumba program, resistance training)
Arm III (HIIT, resistance training)
Arm IV (supervised moderate intensity walking program)
Arm V (usual physical activity)
Participants wear Fitbit, receive home-based DVD containing instructions to warm-up and cool-down, and brisk walk 30 minutes per day 5 days a week in order to achieve the 150 minutes per week of moderate intensity exercise. Participants also receive resistance training by watching the illustration video and completing 6 total blocks of 2-week per block exercise using the Thera-BandR exercise bands.
Participants wear Fitbit and receive a XBOX system and the video game to strive for at least 3 50-minute medium or high intensity classes per week over 12 weeks. Participants may also take 20-minute classes or a mixture of 50- and 20-minute classes to meet the target. Participants receive resistance training as in Arm I.
Participants wear Fitbit and attend supervised HIIT exercise sessions 3 days per week over 12 weeks. Participants receive resistance training as in Arm I.
Participants wear Fitbit and attend supervised moderate intensity walking sessions weekly for 50-60 each over 12 weeks. Participants undergo resistance training as in Arm I.
Participants wear Fitbit and continue their usual physical activity over 12 weeks.