Exercise Intervention for the Prevention of Prediabetes in Overweight Chinese
PreDiabetes, Insulin Sensitivity
About this trial
This is an interventional prevention trial for PreDiabetes
Eligibility Criteria
Inclusion Criteria:
- overweight/obese Chinese man (25 kg/m2<BMI<32.5 kg/m2) aged between 21 and 60 years old; prediabetes, impaired glucose tolerance (mean 2-h blood glucose ≥7.8 and ≤11.1 mmol/l after a 75-g oral glucose challenge) or impaired fasting glucose (mean fasting blood glucose ≥6.1 mmol/l and ≤7.0 mmol/l and HbA1c levels between 5.7% and 6.4%).
Exclusion Criteria:
- any neurological, musculoskeletal or cardio respiratory condition, which would put them at risk during exercise or inhibit their ability to adapt to an exercise program; any subject participated in a regular vigorous exercise and/or diet program more than 2 times per week in the 3 months prior to recruitment; any subject who is taking medicine, especially antibiotics in the past week prior to study.
Sites / Locations
- Department of Medicine
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
No Intervention
High intensity intervention
Moderate intensity intervention
non-exercise group
Exercise intervention at 70 to 80% of estimated heart rate maximum for 12 weeks.
Exercise intervention at 50 to 70% of estimated heart rate maximum for 12 weeks.
Participants will not receive any type of exercise training.