Exercise Trial in Chronic Kidney Disease (AWARD)
Chronic Kidney Disease
About this trial
This is an interventional other trial for Chronic Kidney Disease focused on measuring Chronic kidney disease, Exercise, Aerobic capacity, Learning and memory, Executive function, Endothelial function
Eligibility Criteria
Inclusion Criteria:
- Stage 3-4 Chronic kidney disease (estimated GFR 15-45)
- Age 60 to 85
- English Speaking
Exclusion Criteria:
- Dementia or cognitive impairment
- Renal transplant
- NY Heart Association class 3-4 heart failure
- Severe Chronic Lung Disease
- Unstable angina or coronary revascularization within the last 3 months
- Orthopedic problems that would preclude aerobic exercise training
- Known, untreated infection
- Disabling arthritis
- Uncontrolled arrhythmia
- More than 14 alcoholic drinks per week
Sites / Locations
- Baltimore VA Medical Center / University of Maryland Medical Center
- Tufts Medical Center
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Aerobic exercise
Health Education
12 months of treadmill walking and strength training exercise. Exercise is gradually progressed in walking speed and time on the treadmill based on the individual's tolerance, abilities, and safety. For months 1-6 exercise will take place 3 times per week at the research center. For months 6-12 exercise will take place 2 times per week at the center and 1 time per week at home.
12 months of Health education sessions which will cover topics important to older adults (safe travel, age-appropriate preventative screenings, resources for reliable health information, and topics relevant to chronic kidney disease). For months 1-6 classes will take place 1 time per week. For months 6-12 classes will take place 1 time per month.