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Extracorporeal Membrane Oxygenation Effect in Prolonged Cardiopulmonary Resuscitation

Primary Purpose

Cardiopulmonary Resuscitation, Cardiac Arrest, Ventricular Tachycardia

Status
Completed
Phase
Locations
Taiwan
Study Type
Observational
Intervention
Extracorporeal membrane oxygenation
Sponsored by
National Taiwan University Hospital
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an observational trial for Cardiopulmonary Resuscitation focused on measuring ECMO, CPR

Eligibility Criteria

18 Years - 85 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: CPR > 10 min without return of spontaneous circulation Exclusion Criteria: CPR with traumatic origin unless bleeding was under control, previous irreversible brain damage, terminal status of malignancy, and the age over 75 years. For the patients with post-cardiotomy shock requiring ECLS in the operating theater because of an inability of weaning from cardiopulmonary bypass, they were excluded as well from this ECPR cohort since they did not receive cardiac massage. The patients that had signed "Do-Not-Resuscitate" (DNR) consent were also excluded from ECLS deployment.

Sites / Locations

  • National Taiwan University Hospital

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

First Posted
September 12, 2005
Last Updated
January 16, 2009
Sponsor
National Taiwan University Hospital
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1. Study Identification

Unique Protocol Identification Number
NCT00173615
Brief Title
Extracorporeal Membrane Oxygenation Effect in Prolonged Cardiopulmonary Resuscitation
Study Type
Observational

2. Study Status

Record Verification Date
January 2009
Overall Recruitment Status
Completed
Study Start Date
April 1996 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
December 2006 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
National Taiwan University Hospital

4. Oversight

5. Study Description

Brief Summary
Analysis of the patients' data who were rescued with extracorporeal membrane oxygenation and without ECMO. The survival rate and the weaning rate were analyzed to see the effect of ECMO on the prolonged CPR.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Cardiopulmonary Resuscitation, Cardiac Arrest, Ventricular Tachycardia, Ventricular Fibrillation
Keywords
ECMO, CPR

7. Study Design

Enrollment
100 (false)

8. Arms, Groups, and Interventions

Intervention Type
Procedure
Intervention Name(s)
Extracorporeal membrane oxygenation

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
85 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: CPR > 10 min without return of spontaneous circulation Exclusion Criteria: CPR with traumatic origin unless bleeding was under control, previous irreversible brain damage, terminal status of malignancy, and the age over 75 years. For the patients with post-cardiotomy shock requiring ECLS in the operating theater because of an inability of weaning from cardiopulmonary bypass, they were excluded as well from this ECPR cohort since they did not receive cardiac massage. The patients that had signed "Do-Not-Resuscitate" (DNR) consent were also excluded from ECLS deployment.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Yih-Sharng Chen, MD, PhD
Organizational Affiliation
National Taiwan University Hospital
Official's Role
Principal Investigator
Facility Information:
Facility Name
National Taiwan University Hospital
City
Taipei
ZIP/Postal Code
100
Country
Taiwan

12. IPD Sharing Statement

Citations:
PubMed Identifier
14411374
Citation
KOUWENHOVEN WB, JUDE JR, KNICKERBOCKER GG. Closed-chest cardiac massage. JAMA. 1960 Jul 9;173:1064-7. doi: 10.1001/jama.1960.03020280004002. No abstract available.
Results Reference
background
PubMed Identifier
11320390
Citation
Eisenberg MS, Mengert TJ. Cardiac resuscitation. N Engl J Med. 2001 Apr 26;344(17):1304-13. doi: 10.1056/NEJM200104263441707. No abstract available.
Results Reference
background
PubMed Identifier
6877286
Citation
Bedell SE, Delbanco TL, Cook EF, Epstein FH. Survival after cardiopulmonary resuscitation in the hospital. N Engl J Med. 1983 Sep 8;309(10):569-76. doi: 10.1056/NEJM198309083091001.
Results Reference
background
PubMed Identifier
16325314
Citation
Cooper S, Janghorbani M, Cooper G. A decade of in-hospital resuscitation: outcomes and prediction of survival? Resuscitation. 2006 Feb;68(2):231-7. doi: 10.1016/j.resuscitation.2005.06.012. Epub 2005 Dec 1.
Results Reference
background
PubMed Identifier
16352966
Citation
Weil MH, Fries M. In-hospital cardiac arrest. Crit Care Med. 2005 Dec;33(12):2825-30. doi: 10.1097/01.ccm.0000191265.20007.9d.
Results Reference
background
PubMed Identifier
12535808
Citation
Chen YS, Chao A, Yu HY, Ko WJ, Wu IH, Chen RJ, Huang SC, Lin FY, Wang SS. Analysis and results of prolonged resuscitation in cardiac arrest patients rescued by extracorporeal membrane oxygenation. J Am Coll Cardiol. 2003 Jan 15;41(2):197-203. doi: 10.1016/s0735-1097(02)02716-x.
Results Reference
background
PubMed Identifier
9133537
Citation
Cummins RO, Chamberlain D, Hazinski MF, Nadkarni V, Kloeck W, Kramer E, Becker L, Robertson C, Koster R, Zaritsky A, Bossaert L, Ornato JP, Callanan V, Allen M, Steen P, Connolly B, Sanders A, Idris A, Cobbe S. Recommended guidelines for reviewing, reporting, and conducting research on in-hospital resuscitation: the in-hospital 'Utstein style'. American Heart Association. Circulation. 1997 Apr 15;95(8):2213-39. doi: 10.1161/01.cir.95.8.2213. No abstract available.
Results Reference
background
PubMed Identifier
1611332
Citation
Tunstall-Pedoe H, Bailey L, Chamberlain DA, Marsden AK, Ward ME, Zideman DA. Survey of 3765 cardiopulmonary resuscitations in British hospitals (the BRESUS Study): methods and overall results. BMJ. 1992 May 23;304(6838):1347-51. doi: 10.1136/bmj.304.6838.1347.
Results Reference
background
PubMed Identifier
9824069
Citation
Vincent JL, de Mendonca A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med. 1998 Nov;26(11):1793-800. doi: 10.1097/00003246-199811000-00016.
Results Reference
background
PubMed Identifier
18603291
Citation
Chen YS, Lin JW, Yu HY, Ko WJ, Jerng JS, Chang WT, Chen WJ, Huang SC, Chi NH, Wang CH, Chen LC, Tsai PR, Wang SS, Hwang JJ, Lin FY. Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis. Lancet. 2008 Aug 16;372(9638):554-61. doi: 10.1016/S0140-6736(08)60958-7. Epub 2008 Jul 4.
Results Reference
derived

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Extracorporeal Membrane Oxygenation Effect in Prolonged Cardiopulmonary Resuscitation

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