Family History Study on Cancer Risk
Lynch Syndrome, Colorectal Cancer, Breast Cancer
About this trial
This is an interventional health services research trial for Lynch Syndrome focused on measuring cancer, family characteristics, genetic predisposition, primary care
Eligibility Criteria
Inclusion Criteria:
- Adult patients with ≥2 years of prior membership, ≥1 clinical visit in prior two years, and a listed email are eligible
- Patients must also have received healthcare services during the past 2 years at Kaiser Permanente Northern California (KPNC) sampling sites
Exclusion Criteria:
- Patients outside the targeted geographic area
- Patients who cannot speak or read English (given some survey instruments are validated only in English)
- Kaiser Permanente Northern California members in the no-contact database for research studies
Sites / Locations
- Division of Research, Kaiser Permanente Northern CaliforniaRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Other
Experimental
Experimental
Comparator 1
Comparator 2
Comparator 3
Participants will have their cancer risk assessed via usual care. Usual Care is defined as provider capture of family history during a clinical encounter and its entry into the electronic health record (EHR). Participants will take the a patient reported outcomes (PRO) survey once to assess participants experience, perspectives and thoughts on cancer, cancer risk, and cancer risk assessments.
Participants will have their cancer risk assessed using a short, standardized web-based questionnaire that will populate validated cancer risk models (such as Breast Cancer Risk Assessment Tool/Gail model 2, PREMM and/or MMRpro) which will take 5-10 minutes to complete. Following the cancer risk assessment, participants will be asked to take a PRO survey. PRO surveys will also be administered at the time of the cancer risk assessment and then 6 and 12 months following.
Participants will have their cancer risk assessed using a more detailed, full version of the family history survey than the one comparator 2 participants take. This version is a full pedigree assessment, which entails family health history for all 1st, 2nd, and 3rd-degree relatives. Time needed for completion is 15-25 minutes, depending on family size and cancer risk. Participants will also be asked to take the PRO survey following the full cancer risk assessment and also at 6 and 12 months.