Feasibility of the Mindfulness-Based Stress Reduction Intervention for Black Women Living With HIV Supplement

Feasibility of the Mindfulness-Based Stress Reduction Intervention for Black Women Living With HIV Supplement

Feasibility of the Mindfulness-Based Stress Reduction Intervention for Black Women Living With HIV Administrative Supplement

In our Supplement Aim we will conduct a two-arm randomized pilot test of the adapted intervention compared to a usual care control group among 30 African American/Black women with HIV (15/arm) to assess the feasibility and acceptability of the mindfulness-based stress reduction among women with HIV with mild cognitive impairment. Feasibility will be assessed by our ability to (1) recruit, randomize, and retain participants and (2) deliver the intervention per the manual, as well as (3) participants adherence to home practices and assignments. Acceptability will be assessed via qualitative data (focus group input regarding participants' satisfaction with the intervention and intent to continue using the practices), as well quantitative data (satisfaction survey).

Mindfulness-based stress reduction sessions received by the treatment group will include an orientation, approximately 8 intervention sessions, and an exit interview.

The traditional mindfulness intervention consists of the following: (1) orientation; (2) a series of eight weekly session of 2.5 to 3 hours; (3) a silent retreat during the between weeks 4 and 6; (4) daily home assignments including formal and informal mindfulness practices; and (5) didactic presentations on stress and the consequences of stress.

Feasibility will be assessed through the following: recruitment of 30 participants over a period of 12 weeks (3 months); completion of post-intervention survey and exit interview by 75% of participants; 66% (n=9-10) of participants will attend 6 out of 8 sessions remotely or face-to-face and 50% (n= 7-8) of participants will attend the all-day retreat; and 80% of participants (n=24) will be retained throughout the study. We will assess fidelity with the goal of 80% or greater adherence to the intervention manual. Percent of home practice completed over 8 weeks will be assessed via self-report.

participants' satisfaction with the intervention including length, content, interventionists, practices, setting, and contextual factors.

Speed of information processing, Executive Function, Learning and memory, verbal fluency and everyday functioning.

Adherence will be measured by the single-item antiretroviral therapy question. Higher scores indicate better antiretroviral therapy adherence.

Perceived stress will be measures using the perceived stress scale (PSS), with higher scores indicating higher perceived stress.

Inclusion Criteria: Cisgender females HIV seropositive 18 years of age or older English speaking An active patient at the local HIV ambulatory clinic in Alabama. No history of neurological (including dementia diagnosis) No history of severe psychiatric (e.g., schizophrenia or bipolar disorder) disorders Exclusion Criteria: Non-English speaking Appear temporarily impaired (e.g., intoxicated) Not willing to or legally unable to provide informed consent.

The University of Alabama at Birmingham maintains the following universal data sharing policy for all investigators: Data will be made available, in accordance with the NIH Data Sharing Policy (http://grants.nih.gov/grants/policy/data_sharing) to all researchers in both the private and public sector free or for a nominal charge and with minimal restriction. In some cases the institution may determine that the public and the research community are better served by a licensing program whether or not patents have been filed. This may be relevant, for example, if a tool is best distributed under license to guarantee reagent availability and quality. As a means of sharing knowledge, NIH encourages grantees to arrange for publication of NIH-supported original research in primary scientific journals. We therefore will strive to publish our findings in a timely manner and acknowledge that the research was supported by the NIH.