Finger-prick Autologous Blood (FAB) for Use in Dry Mouth
Xerostomia, Xerostomia Due to Radiotherapy, Xerostomia Due to Hyposecretion of Salivary Gland
About this trial
This is an interventional treatment trial for Xerostomia focused on measuring Fingerprick Autologous Blood
Eligibility Criteria
Inclusion Criteria:
- Patients diagnosed with dry mouth and are on or have refused treatment e.g. spray or mouthwash
Exclusion Criteria:
- Patients who do not have capacity to consent
- Patients with immunodeficiency
- Infected finger or systemic infection or on systemic antibiotics for infection
- Patients with active microbial infection, acute herpes simplex, herpes zoster or infected mouth ulcers
- Pregnant or breast feeding women
- Fear of needles and unwillingness to carry out repeated finger pricks
- Patients with frank oral ulceration
Sites / Locations
Arms of the Study
Arm 1
Experimental
Fingerprick Autologous Blood (FAB) for Use in Dry Mouth
All patients recruited will receive a 10ml saline mouth wash. Half will produce a blood-saline mixture from this mouthwash (preparation details below) and the other half will only use standard saline mouthwash. Each group will use their respective mouthwash 4 times a day for 4 weeks. During the following 4 weeks, participants will use the other mouthwash treatment. In the final 4 weeks, neither group of patients will be using either mouthwash. Patients will be assessed at week 0, 2, 4, 6, 8, 10 and 12. However only clinic visits 0, 4, 8 and 12 will require clinic visits. During weeks 2, 6, and 10 the patients will fill out the questionnaire at home.