Fluid Volume-hypotension Association in Cesarean Under Neuraxial Anesthesia (VOHOCUNA)
Cesarean Section

About this trial
This is an interventional treatment trial for Cesarean Section focused on measuring Epidural anesthesia, Spinal anesthesia, Combined spinal-epidural anesthesia, Fluid therapy, Crystalloid, Colloid
Eligibility Criteria
Inclusion Criteria:
- 21-40 yr
- First time of delivery
- ASA status I-II
- No premature
- No genetic and infectious diseases
- Chinese
Exclusion Criteria:
- < 21 yr
- > 40 yr
- Subjects with cardiac and pulmonary disorders
- Dislocation of placenta
- Pregnant hypertension
- Allergy to local anesthetics
- Unwilling to cooperation
- Need intraoperative administration of vascular active agents
- With significant delivery side effects
- With contradictions of neuraxial anesthesia
Sites / Locations
- Nanjing Maternity and Child Health Care Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Epidural crystalloid
Epidural colloid
Spinal crystalloid
Spinal colloid
CSEA crystalloid
CSEA colloid
Crystalloid (Ringer's Lactate) is given pre-, co- and post-epidural anesthesia in patients undergoing Cesarean section
Colloid (6% hydroxyethyl starch) is given pre-, co- and post-epidural anesthesia in patients undergoing Cesarean section
Crystalloid (Ringer's Lactate) is given pre-, co- and post-spinal anesthesia in patients undergoing Cesarean section
Colloid (6% hydroxyethyl starch) is given pre-, co- and post-spinal anesthesia in patients undergoing Cesarean section
Crystalloid (Ringer's Lactate) is given pre-, co- and post-CSEA anesthesia in patients undergoing Cesarean section
Colloid (6% hydroxyethyl starch) is given pre-, co- and post-CSEA anesthesia in patients undergoing Cesarean section