fNIRS-based Neurofeedback Intervention for Cognitive Control Improvement in Emotional Overeating (Cemov)
Hyperphagia
About this trial
This is an interventional prevention trial for Hyperphagia focused on measuring emotional overeating, functional near infraRed spectroscopy, neurofeedback, cognitive control
Eligibility Criteria
Eligibility
Study A :
- Minimum age : 18 Years
- Maximum Age : 50 Years
- Sex : women or men
Inclusion Criteria :
- Normal Body Mass Index (18-25),
- Right-handlers
- Affiliated to a social security scheme
- Having given a free, informed and written consent
Exclusion Criteria :
Related to the study - Insufficient command of French
Related to Magnetic Resonance Imagine
- Implantable cardiac pacemaker or defibrillator;
- Neurosurgical clips;
- Cochlear implants;
- Neural or peripheral stimulator;
- Foreign orbital or brain metallic foreign bodies;
- Endoprostheses implanted for less than 4 weeks and osteosynthesis materials placed for less than 6 weeks;
- Claustrophobia. Related to near infra Red spectroscopy
- Hairs that do not allow proper near infra Red spectroscopy measurement upon ligh blockage
Study B
- Minimum age : 18 Years
- Maximum Age : 25 Years
- Sex : women
Inclusion Criteria :
- Normal BMI (18-25),
- Right-handlers
- Affiliated to a social security scheme
- Having given a free, informed and written consent
- Based on emotional overeating questionary : having emotional overeating episodes > 6 days in a month for at least one negative emotion
Exclusion Criteria :
Related to the study
- Insufficient command of French
- Excessive consumption of alcohol or other psychoactive substances (determined on the basis of the Alcohol Use Disorders Identification Test questionnaires - excluded if score > 12 and "Car, Relax, Alone, Forget, Friends, Trouble" questionnaire - excluded if score> 1 " yes ")
- Eating disorders ("sick, control, one stone, fat, food" questionnaire >2)
- Food addiction (Yale Food Addiction Score 2.0, score >2
- With psychoactive treatment
- Digestive or gastric disorders
Related to magnetic resonance imaging
- Implantable cardiac pacemaker or defibrillator;
- Neurosurgical clips;
- Cochlear implants;
- Neural or peripheral stimulator;
- Foreign orbital or brain metallic foreign bodies;
- Endoprostheses implanted for less than 4 weeks and osteosynthesis materials placed for less than 6 weeks;
- Claustrophobia.
Related to near infraRed spectroscopy
- Hairs that do not allow proper near infraRed spectroscopy measurement upon ligh blockage
Sites / Locations
- Chu Rennes - PontchaillouRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Other
Experimental
Sham Comparator
Study A
Study B - Neurofeedback
Study B - Control
Validation of the reward system-related fMRI task, as determined by an increased activation on the brain reward structure (striatum) under the task.
The neurofeedback protocol will be the same during the 8 sessions constituting the protocol and taking place over a period of 4 weeks (2 neurofeedback sessions per week, the first and the last one in an MRI context). It will last 15 minutes per session, and during each session, the volunteer will have to increase the brain activity of his/her dlPFC using a visual gauge representing the "activity level" of his/her own dlPFC. No specific instructions will be given to the volunteer so that he/she can develop his/her own internal strategy to increase this "activity level".
In the control group with neurofeedback sham, the participants will receive the same instruction but will be shown a random signal, the goal being that the control strategy the participant tries to implement is not correlated with the visual feedback provided by the gauge.