Follow-up Study of Transcranial Direct Current Stimulation to Treat Major Depressive Disorder
Major Depressive Disorder
About this trial
This is an interventional treatment trial for Major Depressive Disorder focused on measuring Major depressive disorder, follow-up, relapse, remission, transcranial direct current stimulation
Eligibility Criteria
Inclusion criteria:
Patients from previous studies (ID:USP-HU-001 and ID:USP-HU-002) who:
- received tDCS and responded.
- received tDCS + sertraline and responded.
- received sertraline or placebo and did not respond, and thereafter received tDCS during the cross-over phase and responded.
Exclusion criteria:
Patients from previous studies who:
- received tDCS and did not respond.
- received tDCS + sertraline and did not respond.
- received sertraline or placebo and responded.
- did not respond during the crossover phase.
- do not wish to participate in the present study.
Sites / Locations
- University of Sao Paulo
Arms of the Study
Arm 1
Experimental
Transcranial Direct Current Stimulation
In active stimulation, the anode is placed over the left dorsolateral prefrontal cortex and the cathode is placed over the right prefrontal cortex. They are located five centimeters ventrally of the primary motor area, which are located five centimeters laterally of the central point of the scalp (which is located on the intersection of the sagittal and median curves). The device will deliver a charge of 2mA for 30 minutes. The patient will receive tDCS every other week during the first three months, then once a month during the next three months.