Freshly Manufactured 35kDa Hyaluronan Fragment HA35 for the Treatment of Chronic Wounds
Chronic Wounds
About this trial
This is an interventional treatment trial for Chronic Wounds focused on measuring Hyaluronidase, 35kDa hyaluronan fragment, HA35, Tissue permeability, Chronic wound, Wound healing
Eligibility Criteria
Inclusion Criteria: The chronic wounds of painful diabetic wounds, venous wounds, arterial wounds, traumatic and pressure wounds which had not been closed more than 3 months. All the chronic wounds were clinically presented by surface darkeness and purulent secretions on the wounds, and darkness or redness, swelling, dryness and broken. Surface of the skin immediately surrounding the wounds. Subject agrees to be compliant with study related visit and treatment schedule. Written informed consent. Exclusion Criteria: History of wound healing abnormalities or a medical condition that is known to be associated with abnormal wound healing. Subjects with any known coagulation disorder.
Sites / Locations
- Far East Hospital
Arms of the Study
Arm 1
Experimental
35 kDa HA fragment HA35 injection
100 mg of the freshly made 35 kDa low molecular weight hyaluronan fragment HA35 was injected into the tissue under the heath skin immediately surrounding the chronic wounds