Fronto-parietal tDCS in Severely Brain Injured Patients With Disorders of Consciousness
Vegetative State, Minimally Conscious State, Disorders of Consciousness
About this trial
This is an interventional treatment trial for Vegetative State focused on measuring vegetative state, minimally conscious state, disorder of consciousness, transcranial current direct stimulation, non invasive brain stimulation, neuromodulation
Eligibility Criteria
Inclusion Criteria:
- post comatose patients
- patients in minimally conscious state
- patients with stable condition
- patients free of sedative drugs and Na+ or Ca++ blockers (e.g., carbamazepine) or NMDA receptor antagonist (e.g., dextromethorphan)
Exclusion Criteria:
- premorbid neurology antecedent
- patients in coma
- patients < 28 days after the acute brain injury
- patients with a metallic cerebral implant
- cranioplasty
- shunt
Sites / Locations
- University of Liege
Arms of the Study
Arm 1
Arm 2
Active Comparator
Sham Comparator
anodal tDCS
sham tDCS
Patients will receive anodal tDCS (bilateral fronto-parietal stimulation) during 20 minutes preceded and followed by a clinical assessment (Coma Recovery Scale-Revised) and neurophysiological assessment (8 channels EEG).
Patients will receive sham tDCS (15 second of stimulation) during 20 minutes preceded and followed by a clinical assessment (Coma Recovery Scale-Revised) and neurophysiological assessment (8 channels EEG).