Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study (FILMS)
Stage 2 or 3 Full Thickness Macular Hole
About this trial
This is an interventional treatment trial for Stage 2 or 3 Full Thickness Macular Hole focused on measuring Full thickness macular hole, Internal limiting membrane (ILM), Vitreo retinal surgery, Vitrectomy
Eligibility Criteria
Inclusion Criteria: Idiopathic FTMH of stage 2-3, Duration of hole ≤18 months, Visual acuity equal to or worse than 20/40 in the study eye. Exclusion Criteria: Stage 1 or 4 FTMH, Stage 2-3 FTMH of > 18 months duration, Visual acuity >20/40 in study eye, FTMH related to high myopia (>6 dioptres), FTMH related to trauma, any other causes of decreased vision (ie corneal scarring, age-related macular degeneration, diabetic retinopathy, glaucoma if central and/or paracentral absolute visual field defects present), patient unable to understand English, patient unable to give informed consent.
Sites / Locations
- Royal Victoria Eye and Ear Hospital
- Waterford Regional Hospital
- Aberdeen Royal Infirmary
- Bristol Eye Hospital
- Ninewells Hospital
- Gartnavel General Hospital
- Royal Liverpool Hospital
- Oxford Eye Hospital
- Sunderland Eye Infirmary
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
ILM peeling
No ILM peeling
Combined cataract surgery (phacoemulsification and intraocular lens implantation) and pars plana vitrectomy with postoperative intraocular tamponade with gas, with ILM peeling
combined cataract surgery (phacoemulsification and intraocular lens implantation) and pars plana vitrectomy with postoperative intraocular tamponade with gas without ILM peeling