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Functional Outcomes of Stay Strong Stay Healthy Program

Primary Purpose

Quality of Life, Aging, Memory Loss

Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Resistance Exercise
Sponsored by
University of Missouri-Columbia
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional health services research trial for Quality of Life focused on measuring Elderly, Older, Adults, Resistant Exercise, Strength Training, Cognitive function

Eligibility Criteria

60 Years - undefined (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Age 60 or above
  • Enrollment in Stay Strong Stay Healthy Program
  • Strength training < 2 hours/week for past 3 months

Exclusion Criteria:

  • Not enrolled in Stay Strong Stay Healthy Program
  • Strength training > 2 hours/week for past 3 months
  • Donated more than 463 ml of blood in past 8 weeks
  • Physician discouraged to participate

Sites / Locations

  • University of Missouri-Columbia

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Older adults

Arm Description

Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.

Outcomes

Primary Outcome Measures

Muscle electrical activity
Measurement of muscle electrical activity is made using electromyography technique at baseline and after 8 weeks of resistance exercise.

Secondary Outcome Measures

Exert muscle power/strength
Measurement of muscle power/strength is made using hand dynamometer at baseline and after 8 weeks of resistance exercise.
Muscle mass loss
Changes in the muscle mass is made using dual x-ray absorptiometry technique at baseline and after 8 weeks of resistance exercise.
Ability to think or remember
Changes in ability to think or remember is measured by using standard survey (Self Administered Gerocognitive Exam Form -1) at baseline and after 8 weeks of resistance exercise.

Full Information

First Posted
February 2, 2016
Last Updated
April 2, 2018
Sponsor
University of Missouri-Columbia
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1. Study Identification

Unique Protocol Identification Number
NCT02677363
Brief Title
Functional Outcomes of Stay Strong Stay Healthy Program
Official Title
Functional Outcomes of Stay Strong, Stay Healthy Program
Study Type
Interventional

2. Study Status

Record Verification Date
April 2018
Overall Recruitment Status
Completed
Study Start Date
February 2016 (undefined)
Primary Completion Date
June 2017 (Actual)
Study Completion Date
June 2017 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University of Missouri-Columbia

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures. Strength training can also lead to reduced risk for diabetes, heart disease, arthritis, depression, and obesity; and improves self-confidence, sleep and vitality. Research demonstrates that strength training is extremely effective in helping aging adults with chronic conditions prevent further onset of disease and, in many instances, actually reverse the disease process. In Stay Strong, Stay Healthy Program elderly subjects perform resistance exercise training (RET) twice every week. Past literature suggests that resistance training improved muscle activity, muscle strength, muscle mass, and bone mineral density and total body composition, and adiponectin, insulin sensitivity, fasting blood-glucose (BG), HbA1c1 (long-term marker of BG), blood pressure (BP), blood triglycerides (TGs) and low density lipoproteins (LDL) in healthy and diabetic subjects. The purpose of this study is to measure the changes in the above discussed variables after 8-weeks of resistance exercises.
Detailed Description
Participants will perform resistance exercise for 8 weeks and measurements (anthropometric, electromyography, pulse wave velocity, strength test, dual x-ray absorptiometry, blood enzymes/hormones, and sleep, diet, memory surveys) will be performed pre- and post-exercise program.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Quality of Life, Aging, Memory Loss, Cardiovascular Diseases
Keywords
Elderly, Older, Adults, Resistant Exercise, Strength Training, Cognitive function

7. Study Design

Primary Purpose
Health Services Research
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
20 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Older adults
Arm Type
Experimental
Arm Description
Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.
Intervention Type
Other
Intervention Name(s)
Resistance Exercise
Other Intervention Name(s)
Strength training
Intervention Description
Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.
Primary Outcome Measure Information:
Title
Muscle electrical activity
Description
Measurement of muscle electrical activity is made using electromyography technique at baseline and after 8 weeks of resistance exercise.
Time Frame
Change in muscle electrical activity in 8 weeks in response to resistance exercise program
Secondary Outcome Measure Information:
Title
Exert muscle power/strength
Description
Measurement of muscle power/strength is made using hand dynamometer at baseline and after 8 weeks of resistance exercise.
Time Frame
Change in muscle power/strength in 8 weeks in response to resistance exercise program
Title
Muscle mass loss
Description
Changes in the muscle mass is made using dual x-ray absorptiometry technique at baseline and after 8 weeks of resistance exercise.
Time Frame
Change in muscle mass in 8 weeks in response to resistance exercise program
Title
Ability to think or remember
Description
Changes in ability to think or remember is measured by using standard survey (Self Administered Gerocognitive Exam Form -1) at baseline and after 8 weeks of resistance exercise.
Time Frame
Changes in thinking and cognitive abilities in 8 weeks in response to resistance exercise program

10. Eligibility

Sex
All
Minimum Age & Unit of Time
60 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Age 60 or above Enrollment in Stay Strong Stay Healthy Program Strength training < 2 hours/week for past 3 months Exclusion Criteria: Not enrolled in Stay Strong Stay Healthy Program Strength training > 2 hours/week for past 3 months Donated more than 463 ml of blood in past 8 weeks Physician discouraged to participate
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Stephen D Ball, PhD
Organizational Affiliation
University of Missouri-Columbia
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Missouri-Columbia
City
Columbia
State/Province
Missouri
ZIP/Postal Code
65211
Country
United States

12. IPD Sharing Statement

Plan to Share IPD
No
Citations:
PubMed Identifier
22496538
Citation
Geirsdottir OG, Arnarson A, Briem K, Ramel A, Jonsson PV, Thorsdottir I. Effect of 12-week resistance exercise program on body composition, muscle strength, physical function, and glucose metabolism in healthy, insulin-resistant, and diabetic elderly Icelanders. J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1259-65. doi: 10.1093/gerona/gls096. Epub 2012 Apr 10.
Results Reference
background
PubMed Identifier
3057313
Citation
Sale DG. Neural adaptation to resistance training. Med Sci Sports Exerc. 1988 Oct;20(5 Suppl):S135-45. doi: 10.1249/00005768-198810001-00009.
Results Reference
background
PubMed Identifier
10683360
Citation
Pollock ML, Franklin BA, Balady GJ, Chaitman BL, Fleg JL, Fletcher B, Limacher M, Pina IL, Stein RA, Williams M, Bazzarre T. AHA Science Advisory. Resistance exercise in individuals with and without cardiovascular disease: benefits, rationale, safety, and prescription: An advisory from the Committee on Exercise, Rehabilitation, and Prevention, Council on Clinical Cardiology, American Heart Association; Position paper endorsed by the American College of Sports Medicine. Circulation. 2000 Feb 22;101(7):828-33. doi: 10.1161/01.cir.101.7.828. No abstract available.
Results Reference
background
PubMed Identifier
21691559
Citation
Mayer F, Scharhag-Rosenberger F, Carlsohn A, Cassel M, Muller S, Scharhag J. The intensity and effects of strength training in the elderly. Dtsch Arztebl Int. 2011 May;108(21):359-64. doi: 10.3238/arztebl.2011.0359. Epub 2011 May 27.
Results Reference
background
PubMed Identifier
15831061
Citation
Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training. Sports Med. 2005;35(4):339-61. doi: 10.2165/00007256-200535040-00004.
Results Reference
background
PubMed Identifier
14639481
Citation
Macaluso A, De Vito G. Muscle strength, power and adaptations to resistance training in older people. Eur J Appl Physiol. 2004 Apr;91(4):450-72. doi: 10.1007/s00421-003-0991-3. Epub 2003 Nov 25.
Results Reference
background
PubMed Identifier
24150062
Citation
Ball S, Gammon R, Kelly PJ, Cheng AL, Chertoff K, Kaume L, Abreu EL, Brotto M. Outcomes of Stay Strong, Stay Healthy in community settings. J Aging Health. 2013 Dec;25(8):1388-97. doi: 10.1177/0898264313507318. Epub 2013 Oct 22.
Results Reference
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