Genes and Phenotype (GAP) A National Resource for Genotype-Phenotype Studies of Immunological and Inflammatory Pathways (GAP)

Genes and Phenotype (GAP) A National Resource for Genotype-Phenotype Studies of Immunological and Inflammatory Pathways

Genes and Phenotype (GAP) A National Resource for Genotype-Phenotype Studies of Immunological and Inflammatory Pathways

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), University of Alabama at Birmingham

The purpose of this study is to enrol generally healthy adults, who are asked to provide a blood sample, to study how the immune system works.

The primary purpose of this research is to develop a better understanding of how the immune system works. By studying immune function in many people, we will be able to determine the range of normal variation. The second purpose is to enroll people who are willing to serve as comparisons in future research studies into the Genotype and Phenotype Research Registry (GAP Registry). Volunteers are asked to provide information on age, ethnicity and medical history. Volunteers are asked to provide a blood sample of up to 100cc and allow us to contact you about additional studies.

Blood sample will be processed to isolate DNA and peripheral blood mononuclear cells, which will be stored in our Biorepository.

This is a registry to enroll healthy individuals who are interested in being contacted about research studies they can participate in as a healthy control

Inclusion Criteria: Over age 18 Generally healthy Exclusion Criteria: History of autoimmune disease History of chronic immunodeficiency or chronic viral infections such as Epstein Barr virus, hepatitis or HIV Currently undergoing treatment for cancer Current treatment with immuno-suppressant drugs Pregnancy