Gold Factor on Knee Joint Health and Function
Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic
About this trial
This is an interventional treatment trial for Knee Arthritis focused on measuring Knee joint health, Arthritis, Gold nanoparticles (AuNPs), Knee joint function, Osteoarthritis, Rheumatoid Arthritis
Eligibility Criteria
Inclusion Criteria:
- ≥ 18 and <87 years of age
- Having arthritis
- Suffering from chronic knee pain
- Failed treatments to date - including surgery, Physical Therapy, NSAIDs
- Must agree to maintain the same eating, exercise, and sleep arrangements for the whole duration of the study
Exclusion Criteria:
- Having bacterial, intra-articular, or knee infections
- Had any knee related partial or complete total knee replacement within 3 months prior to the start of the study
- Had recent (3 months prior to start of the study) knee injection
- Currently on NSAIDs
- currently pregnant or lactating
Sites / Locations
- Professional Athletic Orthopedics
Arms of the Study
Arm 1
Arm 2
Arm 3
Other
No Intervention
Active Comparator
Phase 1: double-blinded placebo-controlled Supplement vs Placebo
Washout Phase
Phase 3: Supplement
Phase 1 (8 weeks): Supplement and Placebo groups ingested 3 oz of Supplement and Placebo per day respectively for the first four weeks as a loading dose, and then switched to 2 oz per day for weeks 5 - 8. This phase was double-blinded.
Phase 2 (4 weeks): Both groups underwent a month-long "wash out" period, during which they did not ingest any of the Supplement or Placebo. This lasted from weeks 9-12. This phase was not double-blinded as all participants and the researchers were aware of the wash-out procedure.
Phase 3 (8 weeks): Both groups took the Supplement at 3 oz per day as a loading dose for four weeks (weeks 13 - 16), and then 2 oz per day for the final four weeks (weeks 17 - 20). This phase was open labeled, as all participants and the researchers were aware that all participants were ingesting the Supplement.