Heart and Estrogen-Progestin Replacement Study (HERS)
Coronary Heart Disease
About this trial
This is an interventional prevention trial for Coronary Heart Disease focused on measuring Coronary Heart Disease, Hormone replacement therapy, Estrogen, Postmenopausal women
Eligibility Criteria
Inclusion Criteria: <75 y.o. uterus present postmenopausal evidence of CHD signed consent Exclusion Criteria: MI, CABG, mechanical revascularization within 6 months serum triglyceride >300mg/dl used hormone therapy or estrogen vaginal cream in past 3 months history of DVT or pulmonary embolism history of breast cancer or mammogram suggestive of cancer history of endometrial cancer abnormal uterine bleeding pap smear abnormal SGOT more than 1.2 times normal Disease judged to be fatal within 4 yrs alcoholism, drug abuse NYHA Class IV congestive heart failure uncontrolled hypertension uncontrolled diabetes participation in any other investigational study
Sites / Locations
- University of California San Francisco