High- Versus Low-calcium Water for Bone Health
Orthopedic Disorder, Calcium Metabolism Disorders, Bone Resorption
About this trial
This is an interventional health services research trial for Orthopedic Disorder
Eligibility Criteria
Inclusion Criteria: Body mass index ≥ 18 and < 30 Maintenance of diet and physical activity lifestyle throughout the duration of the study Acceptance of informed consent Exclusion Criteria: Consumption of water with calcium > 150 mg/L Pregnancy (as established by self-declaration), breastfeeding, menopause Inability to follow the study protocol Cardiac, vascular, renal, and oncological disease Neuropsychiatric disease, developmental disorders Disease or past surgery affecting the gastrointestinal tract Drugs that interfere with bone (e.g. corticosteroids) or with fluid balance (e.g. diuretics)
Sites / Locations
- IRCCS Istituto Ortopedico GaleazziRecruiting
Arms of the Study
Arm 1
Experimental
Low-calcium water first, then high-calcium water
Participants drink 1.5 L of the designated water