Home-based vs. Supervised Exercise for People With Claudication
Intermittent Claudication
About this trial
This is an interventional treatment trial for Intermittent Claudication focused on measuring aging, gait, musculoskeletal disorder therapy, peripheral blood vessel disorder, muscle function, muscle strength, quality of life
Eligibility Criteria
Inclusion Criteria:
- Positive history of intermittent claudication assessed by the San Diego Claudication Questionnaire
- Exercise limited by intermittent claudication during a screening treadmill test using the Gardner protocol
- Ankle/brachial index (ABI) less than 0.90 at rest, which decreases to less than 0.73 immediately following the treadmill exercise test
Exclusion Criteria:
- Absence of PAD (peripheral artery disease)
- Asymptomatic PAD (Fontaine stage I)
- Rest pain due to PAD (Fontaine stage III)
- Tissue loss due to PAD (Fontaine stage IV)
- Medical conditions that are contraindicative for exercise according to the American College of Sports Medicine (e.g., acute myocardial infarction, unstable angina, etc.)
- Cognitive dysfunction (mini-mental state examination score less than 24)
Sites / Locations
- General Clinical Research Center, University of Oklahoma Health Sciences Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Active Comparator
1
2
3
Home-based program with progressive increases in exercise duration and intensity (i.e., cadence); walking duration will be longer for the home-based group because the intensity of walking will be lower than the graded treadmill walking performed by the supervised group
Supervised program consisting of graded treadmill walking, with progressive increments in exercise duration from 15 to 40 minutes, and progressive increments in exercise intensity from 50 to 70% of exercise capacity
Light resistance training without any walking exercise