Back to resultsHuman Dopamine Transported Imaging in Cocaine Abuse: 1 - 1
Primary Purpose
Cocaine-Related Disorders
Status
Completed
Phase
Phase 1
Locations
United States
Study Type
Interventional
Intervention
Cocaine
Sponsored by
About this trial
This is an interventional treatment trial for Cocaine-Related Disorders focused on measuring cocaine dependence
Eligibility Criteria
Please contact site for information.
Sites / Locations
- Johns Hopkins University
Outcomes
Primary Outcome Measures
Physiological changes in: heart rate and blood pressure
Subjective effects of cocaine inducements and withdrawal
Psychological effects
Effects of investigational drug
Secondary Outcome Measures
Full Information
NCT ID
NCT00000315
First Posted
September 20, 1999
Last Updated
January 11, 2017
Sponsor
National Institute on Drug Abuse (NIDA)
Collaborators
Johns Hopkins University
1. Study Identification
Unique Protocol Identification Number
NCT00000315
Brief Title
Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1
Official Title
Human Dopamine Transported Imaging in Cocaine Abuse: 1
Study Type
Interventional
2. Study Status
Record Verification Date
November 1996
Overall Recruitment Status
Completed
Study Start Date
November 1996 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
December 2001 (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
National Institute on Drug Abuse (NIDA)
Collaborators
Johns Hopkins University
4. Oversight
5. Study Description
Brief Summary
The purpose of this study is to determine the density of DA transporters during prolonged cocaine abuse and during withdrawal from cocaine use. This aim will test the hypothesis that DA transporters are altered by cocaine abuse and reestablished during withdrawal.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Cocaine-Related Disorders
Keywords
cocaine dependence
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 1
Enrollment
0 (false)
8. Arms, Groups, and Interventions
Intervention Type
Drug
Intervention Name(s)
Cocaine
Primary Outcome Measure Information:
Title
Physiological changes in: heart rate and blood pressure
Title
Subjective effects of cocaine inducements and withdrawal
Title
Psychological effects
Title
Effects of investigational drug
10. Eligibility
Sex
Male
Minimum Age & Unit of Time
21 Years
Maximum Age & Unit of Time
45 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Please contact site for information.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Dean Wong, M.D., Ph.D.
Organizational Affiliation
Johns Hopkins University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Johns Hopkins University
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21287
Country
United States
12. IPD Sharing Statement
Citations:
Citation
JNM Suppl 38(5):35P May 97.
Results Reference
background
Learn more about this trial
Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1
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