Back to resultsICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL
Primary Purpose
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Status
Recruiting
Phase
Phase 3
Locations
China
Study Type
Interventional
Intervention
ICP-022
Chlorambucil
Rituximab
Sponsored by
About this trial
This is an interventional treatment trial for Chronic Lymphocytic Leukemia
Eligibility Criteria
Key Inclusion Criteria:
- Male or female, age ≥65 years old or age >18 years old or <65 years old, age >18 years old or <65 years old shall meet any of the following criteria simultaneously: A.Disease accumulation score (CIRS) > 6;B. Creatinine clearance at 30-69 mL/ min (Cockcroft-Gault assessment)
- Enhanced computed tomography/magnetic resonance imaging (CT/MRI) detection had measurable lesions: at least one lymph node had a maximum axis of more than 1.5 cm and had a measurable vertical dimension
- ECOG physical strength score is 0-2.
- Expected survival time >6 months.
- Voluntary written informed consent prior to screening.
Key Exclusion Criteria:
- Patients with stroke or intracranial hemorrhage in the first 6 months were randomly assigned.
- Hypersensitivity to ICP-022, nitrogen mustard benzoate, rituximab or any other component of the applicable study drug.
- Any mental or cognitive impairment that may limit their understanding of the informed consent, their implementation and their compliance with the study.
- Pregnant and lactating women, or subjects of childbearing age who do not want to use contraception within 180 days from the end of the study period to the end of the study period.
- Conditions in which a potentially life-threatening illness or severe organ dysfunction is not considered appropriate by the investigator.
Note: Other protocol defined Inclusion/Exclusion criteria may apply.
Sites / Locations
- The First Affiliated Hospital of Bengbu Medical College
- Anhui Provincial Cancer Hospital
- The First Affiliated Hospital of Anhui Medical University
- The Fifth Medical Center of PLA General Hospital
- The First Affiliated Hospital of Congqing Medical University
- The Second Affiliated Hospital of Army Medical University
- The First Affiliated Hospital of Xiamen UniversityRecruiting
- Lanzhou University Second Hospital
- Dongguan People's Hospital
- Cancer Prevention and Treatment Center, Sun Yat-sen UniversityRecruiting
- Guangzhou First People's HospitalRecruiting
- Shenzhen People's Hospital
- Affiliated Hospital of Guilin Medical College
- Affiliated Hospital of Hebei University
- Hebei Medical University Second HospitalRecruiting
- The Fourth Hospital of Hebei Medical UniversityRecruiting
- Affiliated Tumor Hospital of Harbin Medical University
- The first Affiliated Hospital of Henan University of Science and Technology
- First Affiliated Hospital of Zhengzhou UniversityRecruiting
- Henan Cancer HospitalRecruiting
- Henan Province HospitalRecruiting
- Zhongnan Hospital of WuHan University
- Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and TechnologyRecruiting
- Yichang Central People's HospitalRecruiting
- Yichang First People's HospitalRecruiting
- The Second Xiangya Hospital of Central South University
- The Third Xiangya Hospital of Central South UniversityRecruiting
- Zhuzhou Central Hospital
- Jiangsu Province HospitalRecruiting
- The First Affiliated Hospital of Soochow University
- Wuxi People's Hospital
- Affiliated Hospital of Xuzhou Medical University
- Subei People's Hospital
- The First Affiliated Hospital of Gannan Medical College
- Jiangxi Cancer HospitalRecruiting
- The First Affiliated Hospital of Nanchang UniversityRecruiting
- Shengjing Hospital of China Medical UniversityRecruiting
- The First Affiliated Hospital of China Medical University
- Affiliated Hospital of Binzhou Medical CollegeRecruiting
- Shandong Cancer Hospita
- Shandong Provincial HospitalRecruiting
- Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
- The Second Affiliated Hospital of Xi´an Jiaotong University
- Sichuan Provincial People's HospitalRecruiting
- West China Hospital of Sichuan University
- Yibin Second People's HospitalRecruiting
- General Hospital of Tianjin Medical UniversityRecruiting
- Hospital of Hematology, Chinese Academy of Medical SciencesRecruiting
- Tianjin Cancer HospitalRecruiting
- The First Affiliated Hospital of Xinjiang Medical University
- The first Affiliated Hospital of Kunming Medical University
- Dongyang People's Hospital
- Shaoyifu Hospital Affiliated to Zhejiang University School of Medicine
- The First Affiliated Hospital of Zhejiang University Medical CollegeRecruiting
- Jinhua Central Hospital
- Ningbo First Hospital
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
ICP-022
Chlorambucil combined with Rituximab
Arm Description
ICP-022 will be orally administered until disease progression or unacceptable toxicity.
Chlorambucil orally administered and Rituximab via IV infusion for 6 cycles.
Outcomes
Primary Outcome Measures
Progression Free Survival (PFS)
Progress-free survival (PFS) was evaluated by the independent review board (IRC) against the IWCLL2018 criteria (Hallek et al., 2018) and the revised lymphoma mitigation assessment criteria (Cheson et al., 2014).
Secondary Outcome Measures
Objective Response Rate (ORR)
Duration Of Response (DOR)
Overall Survival (OS)
Full Information
NCT ID
NCT04578613
First Posted
October 1, 2020
Last Updated
June 2, 2023
Sponsor
Beijing InnoCare Pharma Tech Co., Ltd.
1. Study Identification
Unique Protocol Identification Number
NCT04578613
Brief Title
ICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL
Official Title
A Randomized, Controlled, Open, Multicenter Phase 3 Study to Evaluate ICP-022 Versus Chlorambucil Combined With Rituximab for Primary Treatment of Chronic Lymphocytic Leukemia(CLL)/ Small Lymphocytic Lymphoma(SLL)
Study Type
Interventional
2. Study Status
Record Verification Date
May 2023
Overall Recruitment Status
Recruiting
Study Start Date
January 8, 2021 (Actual)
Primary Completion Date
December 30, 2024 (Anticipated)
Study Completion Date
June 30, 2025 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Beijing InnoCare Pharma Tech Co., Ltd.
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
This is a randomized, multicenter, open-label, Phase 3 study to evaluate the efficacy and safety of ICP-022 versus Chlorambucil plus Rituximab in subjects with Previously Untreated Chronic Lymphocytic Leukemia.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
218 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
ICP-022
Arm Type
Experimental
Arm Description
ICP-022 will be orally administered until disease progression or unacceptable toxicity.
Arm Title
Chlorambucil combined with Rituximab
Arm Type
Active Comparator
Arm Description
Chlorambucil orally administered and Rituximab via IV infusion for 6 cycles.
Intervention Type
Drug
Intervention Name(s)
ICP-022
Intervention Description
ICP-022 at a dose of 150mg, QD
Intervention Type
Drug
Intervention Name(s)
Chlorambucil
Intervention Description
0.5 mg/kg body weight orally on Day 1 and Day 15 of Cycles 1-6
Intervention Type
Drug
Intervention Name(s)
Rituximab
Intervention Description
375 mg/m2 IV infusion on Day 1 of Cycle 1. 500 mg/m2 IV infusion on Day 1 for each of subsequent cycles (Cycles 2-6)
Primary Outcome Measure Information:
Title
Progression Free Survival (PFS)
Description
Progress-free survival (PFS) was evaluated by the independent review board (IRC) against the IWCLL2018 criteria (Hallek et al., 2018) and the revised lymphoma mitigation assessment criteria (Cheson et al., 2014).
Time Frame
Up to 5 years
Secondary Outcome Measure Information:
Title
Objective Response Rate (ORR)
Time Frame
Up to 5 years
Title
Duration Of Response (DOR)
Time Frame
Up to 5 years
Title
Overall Survival (OS)
Time Frame
Up to 5 years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Key Inclusion Criteria:
Male or female, age ≥65 years old or age >18 years old or <65 years old, age >18 years old or <65 years old shall meet any of the following criteria simultaneously: A.Disease accumulation score (CIRS) > 6;B. Creatinine clearance at 30-69 mL/ min (Cockcroft-Gault assessment)
Enhanced computed tomography/magnetic resonance imaging (CT/MRI) detection had measurable lesions: at least one lymph node had a maximum axis of more than 1.5 cm and had a measurable vertical dimension
ECOG physical strength score is 0-2.
Expected survival time >6 months.
Voluntary written informed consent prior to screening.
Key Exclusion Criteria:
Patients with stroke or intracranial hemorrhage in the first 6 months were randomly assigned.
Hypersensitivity to ICP-022, nitrogen mustard benzoate, rituximab or any other component of the applicable study drug.
Any mental or cognitive impairment that may limit their understanding of the informed consent, their implementation and their compliance with the study.
Pregnant and lactating women, or subjects of childbearing age who do not want to use contraception within 180 days from the end of the study period to the end of the study period.
Conditions in which a potentially life-threatening illness or severe organ dysfunction is not considered appropriate by the investigator.
Note: Other protocol defined Inclusion/Exclusion criteria may apply.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
April Huang
Phone
010-66609723
Email
April.huang@innocarepharma.com
Facility Information:
Facility Name
The First Affiliated Hospital of Bengbu Medical College
City
Bengbu
State/Province
Anhui
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yanli Yang
Facility Name
Anhui Provincial Cancer Hospital
City
Hefei
State/Province
Anhui
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kaiyang Ding
Facility Name
The First Affiliated Hospital of Anhui Medical University
City
Hefei
State/Province
Anhui
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qingshu Zeng
Facility Name
The Fifth Medical Center of PLA General Hospital
City
Beijing
State/Province
Beijing
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hang Su
Facility Name
The First Affiliated Hospital of Congqing Medical University
City
Chongqing
State/Province
Chongqing
ZIP/Postal Code
400000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qing Xiao
Facility Name
The Second Affiliated Hospital of Army Medical University
City
Chongqing
State/Province
Chongqing
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qin Wen
Facility Name
The First Affiliated Hospital of Xiamen University
City
Xiamen
State/Province
Fujian
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bing Xu
Facility Name
Lanzhou University Second Hospital
City
Lanzhou
State/Province
Gansu
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Liansheng Zhang
Facility Name
Dongguan People's Hospital
City
Dongguan
State/Province
Guangdong
ZIP/Postal Code
523058
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yirong Jiang
Phone
13688967985
Facility Name
Cancer Prevention and Treatment Center, Sun Yat-sen University
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhongjun Xia
Facility Name
Guangzhou First People's Hospital
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qingshun Wang
Facility Name
Shenzhen People's Hospital
City
Shenzhen
State/Province
Guangdong
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xinyou Zhang
Facility Name
Affiliated Hospital of Guilin Medical College
City
Guilin
State/Province
Guangxi Zhuang Autonomous Region
ZIP/Postal Code
541000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wenyuan Lin
Phone
15878361619
Facility Name
Affiliated Hospital of Hebei University
City
Baoding
State/Province
Hebei
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Luoming Hua
Facility Name
Hebei Medical University Second Hospital
City
Shijiazhuang
State/Province
Hebei
ZIP/Postal Code
h
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jinhai Ren
Facility Name
The Fourth Hospital of Hebei Medical University
City
Shijiazhuang
State/Province
Hebei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lihong Liu
Facility Name
Affiliated Tumor Hospital of Harbin Medical University
City
Ha'erbin
State/Province
Heilongjiang
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qingyuan Zhang
Facility Name
The first Affiliated Hospital of Henan University of Science and Technology
City
Luoyang
State/Province
Henan
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Haiping Yang
Facility Name
First Affiliated Hospital of Zhengzhou University
City
Zhengzhou
State/Province
Henan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mingzhi Zhang
Facility Name
Henan Cancer Hospital
City
Zhengzhou
State/Province
Henan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Keshu Zhou
Facility Name
Henan Province Hospital
City
Zhengzhou
State/Province
Henan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zunmin Zhu
Facility Name
Zhongnan Hospital of WuHan University
City
Wuhan
State/Province
Hubei
ZIP/Postal Code
430071
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fuling Zhou
Facility Name
Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guohui Cui
Facility Name
Yichang Central People's Hospital
City
Yichang
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jingming Guo
Facility Name
Yichang First People's Hospital
City
Yichang
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kaibo Gao
Facility Name
The Second Xiangya Hospital of Central South University
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hongling Peng
Facility Name
The Third Xiangya Hospital of Central South University
City
Changsha
State/Province
Hunan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jing Liu
Facility Name
Zhuzhou Central Hospital
City
Zhuzhou
State/Province
Hunan
ZIP/Postal Code
412007
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guoyu Hu
Phone
13707333899
Facility Name
Jiangsu Province Hospital
City
Nanjing
State/Province
Jiangsu
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianyong Li
First Name & Middle Initial & Last Name & Degree
Wei Xu
Facility Name
The First Affiliated Hospital of Soochow University
City
Suzhou
State/Province
Jiangsu
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhengming Jing
Facility Name
Wuxi People's Hospital
City
Wuxi
State/Province
Jiangsu
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xin Zhou
Facility Name
Affiliated Hospital of Xuzhou Medical University
City
Xuzhou
State/Province
Jiangsu
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhenyu Li
Facility Name
Subei People's Hospital
City
Yangzhou
State/Province
Jiangsu
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jian Gu
Facility Name
The First Affiliated Hospital of Gannan Medical College
City
Ganzhou
State/Province
Jiangxi
ZIP/Postal Code
341004
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yijian Chen
Phone
13576749402
Facility Name
Jiangxi Cancer Hospital
City
Nanchang
State/Province
Jiangxi
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yuerong Shuang
Facility Name
The First Affiliated Hospital of Nanchang University
City
Nanchang
State/Province
Jiangxi
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fei Li
Facility Name
Shengjing Hospital of China Medical University
City
Dalian
State/Province
Liaoning
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wei Yang
Facility Name
The First Affiliated Hospital of China Medical University
City
Shenyang
State/Province
Liaoning
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yan Li
Facility Name
Affiliated Hospital of Binzhou Medical College
City
Binzhou
State/Province
Shandong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wenzheng Yu
Facility Name
Shandong Cancer Hospita
City
Jinan
State/Province
Shandong
ZIP/Postal Code
250117
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zengjun Li
Phone
13642138692
Facility Name
Shandong Provincial Hospital
City
Jinan
State/Province
Shandong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xin Wang
Facility Name
Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200025
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianqing Mi
Facility Name
The Second Affiliated Hospital of Xi´an Jiaotong University
City
Xi'an
State/Province
Shanxi
ZIP/Postal Code
710000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Aili, He
Facility Name
Sichuan Provincial People's Hospital
City
Chengdu
State/Province
Sichuan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiaobing Huang
Facility Name
West China Hospital of Sichuan University
City
Chengdu
State/Province
Sichuan
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ting Niu
Facility Name
Yibin Second People's Hospital
City
Yibin
State/Province
Sichuan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shihua Huang
Facility Name
General Hospital of Tianjin Medical University
City
Tianjin
State/Province
Tianjin
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rong Fu
Facility Name
Hospital of Hematology, Chinese Academy of Medical Sciences
City
Tianjin
State/Province
Tianjin
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lugui Qiu
First Name & Middle Initial & Last Name & Degree
Shuhua Yi
Facility Name
Tianjin Cancer Hospital
City
Tianjin
State/Province
Tianjin
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lihua Qiu
First Name & Middle Initial & Last Name & Degree
Yafei Wang
Facility Name
The First Affiliated Hospital of Xinjiang Medical University
City
Ürümqi
State/Province
Xinjiang Uygur Autonomous Region
ZIP/Postal Code
830011
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianhua Qu
Ext
0991-4362974
Facility Name
The first Affiliated Hospital of Kunming Medical University
City
Kunming
State/Province
Yunnan
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yun Zeng
Facility Name
Dongyang People's Hospital
City
Dongyang
State/Province
Zhejiang
ZIP/Postal Code
322199
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gongqiang Wu
Phone
13757950788
Facility Name
Shaoyifu Hospital Affiliated to Zhejiang University School of Medicine
City
Hangzhou
State/Province
Zhejiang
ZIP/Postal Code
310026
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jin Zhang
Facility Name
The First Affiliated Hospital of Zhejiang University Medical College
City
Hangzhou
State/Province
Zhejiang
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jie Jin
Facility Name
Jinhua Central Hospital
City
Jinhua
State/Province
Zhejiang
ZIP/Postal Code
321000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Huixian Hu
Phone
13588652288
Facility Name
Ningbo First Hospital
City
Ningbo
State/Province
Zhejiang
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guifang Ouyang
12. IPD Sharing Statement
Plan to Share IPD
No
Learn more about this trial
ICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL
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