Ideal Time of Oxytocin Infusion During Cesarean Section (I-TOPICS)
Blood Loss, Surgical, Postpartum Hemorrhage, Bleed Pregnancy
About this trial
This is an interventional treatment trial for Blood Loss, Surgical
Eligibility Criteria
Inclusion Criteria:
- Women undergoing cesarean section at Loyola Hospital
- Women who read and speak the English and/or Spanish language
- Women age 18 or older
Exclusion Criteria:
- Women who deliver vaginally
- Gestation under 37 weeks and 0 days
- Women with coagulopathies
- Multiple gestation pregnancies
- Antepartum hemorrhage for example abruption
- Placental abnormalities for example previa, accreta
Sites / Locations
- Loyola University Medical Center
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Active Comparator
Control (Group A)
Intervention (Group B)
One bag of 500 ml 0.9% NaCl (normal saline) will be hung by Anesthesia when the fetal anterior shoulder delivers. After the placenta is delivered, then one bag of 500 ml 0.9% NaCl with 30 units of Oxytocin (Oxytocin solution) will be hung by Anesthesia. This amount of fluid is part of standard of care.
One bag of 500 ml 0.9% NaCl with 30 units of Oxytocin (Oxytocin solution) will be hung by Anesthesia when the fetal anterior shoulder delivers. After the placenta is delivered, then one bag of 500 ml 0.9% NaCl (normal saline) will be hung by Anesthesia. This amount of fluid is part of standard of care.