Impact of a Low-Carbohydrate Diet in Pediatric Type 1 Diabetes
Type 1 Diabetes
About this trial
This is an interventional treatment trial for Type 1 Diabetes focused on measuring Low Carbohydrate Diet, Standard Carbohydrate Diet
Eligibility Criteria
Inclusion Criteria:
- Diagnosed with T1DM for at least 12 months
- Age 13 to 21 years
- Total daily dose of insulin 0.5 to 1.25 units/kg/day
- Current use of an insulin pump and CGM
- HbA1c between 7% and 10%
- Tanner stage 3 to 5 on physical exam
- Participant or parent of participant use of smart phone
- Able to read and speak English
Exclusion Criteria:
- Any episode of diabetic ketoacidosis (DKA) in the last 12 months
- Any episode of severe hypoglycemia (defined as requiring assistance from another person, including coma, seizures, or episodes requiring glucagon, IV dextrose or oral carbohydrate administered by another person) in the last 12 months
- Any prior abnormal fasting lipid panel (LDL > 130)
- Additional dietary restrictions
- Following a weight-loss or otherwise restrictive diet
- Use of medication or supplements other than insulin to control blood glucose
- Use of medication or other supplements to lower lipids
- Pregnancy or breast feeding
- History of hemoglobinopathy
Sites / Locations
- Vanderbilt University Medical Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
No Intervention
Low Carbohydrate Diet
Standard Carbohydrate Diet
No Dietary Recommendations
The investigators will prescribe isocaloric diets equaling the estimated energy requirements of the Institute of Medicine. Participants on the LCD intervention will consume 25-35% of total daily intake from carbohydrates, 45-65% from fat and 10-30% from protein.
The investigators will prescribe isocaloric diets equaling the estimated energy requirements of the Institute of Medicine. Participants on the SCD intervention will consume 45-65% of total daily caloric intake from carbohydrates, 25-35% from fat and 10-30% from protein.
This group will serve as a control that receives the same number of education sessions as LCD and SCD group to teach general diabetes management but without specific dietary recommendations.