Impact of Continuous Regional Analgesia in Severe Trauma Patients (ALRréa)
Limb Fracture
About this trial
This is an interventional other trial for Limb Fracture focused on measuring Intensive Care Unit ; limb fracture ; regional analgesia
Eligibility Criteria
Inclusion Criteria:
- Patient older than 18 years
- Multiple trauma Patient ( with or without head trauma)
- Patient admitted to ICU
- Patient with limb fracture (s)
- Patient requiring sedation and mechanical ventilation for more than 48h
- Patient affiliated to a social security system
- Patient whose informed consent was obtained from the family
Exclusion Criteria:
- Patient currently enrolled in another trial
- Patient with coagulation disorders
- Patient whose access to the puncture sites is not feasible (underlying lesions)
- Patient with allergies to local anesthetics (LA)
- Patient whose family did not give informed consent
- Patient younger than 15 years and 3 months
- Tetraplegic Patient
- Dying patients
- Patients with more than 3 different fracture sites
Sites / Locations
- University hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Continuous Regional Analgesia group
Control Group
Sedation using midazolam and sufentanil: Multi-Daily adjustment of doses every 4 hours using Behavioral Pain Scale score <4 and Ramsay Score > 4 + perinerval block catheter from 0 to 24h after admission in intensive care unit using ropivacaine 0.2% with a continuous infusion at 1mL/10 Kg /H
group with general anesthesia and without locoregional anesthesia: Sedation using midazolam and sufentanil: Multi-Daily adjustment of doses every 4 hours using Behavioral Pain Scale score <4 and Ramsay Score > 4