Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study (POLLAR)

It has been demonstrated that allergic rhinitis (AR) reduces sleep quality by some components such as nasal obstruction. Pollution and allergen exposure worsening AR, sleep quality is deteriorated. Sleep is associated to physical and mental health, alterations in sleep could explain the link between AR and work productivity diminution, impairment in daily activities or emotional problems. However, interactions between air pollution, sleep and allergic diseases are insufficiently understood. The main objective of this study is to determine the impact of pollution and pollens on sleep parameters.

Over 150 million people have allergic rhinitis (AR) in Europe and around 30% have uncontrolled AR during allergen exposure. It has been demonstrated that AR reduces sleep quality by some components such as nasal obstruction. Pollution and allergen exposure worsening AR, sleep quality is deteriorated. Sleep is associated to physical and mental health, alterations in sleep could explain the link between AR and work productivity diminution, impairment in daily activities or emotional problems. However, interactions between air pollution, sleep and allergic diseases are insufficiently understood. Moreover, the prevalence of OSA in patients with AR is higher than in subjects without AR. Nasal obstruction could explain the increased risk of OSA. This prospective, open study will compare sleep quality in 2 different groups: AR patients and patients without AR during the pollen season and outside the pollen season.The main objective is to determine the impact of pollution and pollens on sleep parameters for subjects with AR

Sleep Apnea, Allergic Rhinitis, Allergic Asthma, Pollution Exposure, Pollution Related Respiratory Disorder

Prospective, open study comparing sleep quality in 2 different groups: AR patients and patients without AR during the pollen season and outside the pollen season.

Volunteers without allergic rhinitis and no sleep apnea will have sleep and pollution exposure recordings

Pollution exposure and sleep data will be recorded by pollution sensor and polysomnography respectively. In order to compare the variations according to the pollinisation season and the allergic rhinitis status of the patients.

Change in AHI according to the level of pollution particle matters and volatile organic compounds (VOCs)

Change in Pittsburgh score according to the level of pollution particle matters and volatile organic compounds (VOCs)

Change in EQ-5D score according to the level of pollution particle matters and volatile organic compounds (VOCs)

To analyze variations in medications and impact on sleep during the pollen season and outside the pollen season.

Change in number of medications (antiallergics and hypnotics) according to the level of pollution particle matters and volatile organic compounds (VOCs)

Inclusion Criteria: 18-65 years Be able to use an application on a personal smartphone Patient non treated for OSA Be legally able to give consent Person affiliated to social security Exclusion Criteria: - Being unable to understand, follow objectives and methods due to cognition or language problems Subjects listed in articles L1121-5 à L1121-8: Pregnant women, feeding and parturient; subject under administrative or judicial control, persons who are protected under the act.