Impact of Rotational Atherectomy on Coronary Microcirculation (MICRO-ROTA)
Stable Angina, Coronary Artery Disease
About this trial
This is an interventional treatment trial for Stable Angina focused on measuring Rotational atherectomy, Conventional stenting, CMD, Microcirculation, Index of microcirculatory resistance, IMRangio
Eligibility Criteria
Inclusion Criteria: Patient diagnosed with stable coronary artery calcified lesion requiring Percutaneous coronary intervention Exclusion Criteria: patients with a history of old myocardial infarction or history of coronary artery bypass grafting (CABG) or Percutaneous coronary intervention PCI Patients with signs of chronic infection, prolong usage of corticosteroids or compromised immune system patients had contraindication of adenosine triphosphate (ATP); had a history of liver or renal function dysfunction Patients with dementia Patients being referred to CABG unable to provide informed consent; had pregnancy or life span < 1 year. Presence of sever structural valvular heart disease Presence of significant left main disease Unability to measure the index of microcirculatory resistance due to (death or retraction from the study ...etc) Inability to perform successful PCI
Sites / Locations
- Lithuanian University of Health SciencesRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Rotational Atherectomy
Conventional Stenting
Patients who are scheduled to have rotational atherectomy will be labeled in this group; patients in this group will have invasive and non-invasive microvascular testing before and after the rotational atherectomy procedure.
Patients who are scheduled to have conventional stenting will be labeled in this group; patients in this group will have invasive and non-invasive microvascular testing before and after the conventional stenting procedure.