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Implementation and Evaluation of a Family-based Intervention Program for Children of Mentally Ill Parents (CHIMPs)

Primary Purpose

Schizophrenia and Disorders With Psychotic Features, Mood Disorders, Neurotic Disorders

Status
Completed
Phase
Not Applicable
Locations
International
Study Type
Interventional
Intervention
CHIMPS intervention
Sponsored by
Silke Wiegand-Grefe, Prof. Dr.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Schizophrenia and Disorders With Psychotic Features focused on measuring children of mentally ill parents, family intervention, randomized controlled trial

Eligibility Criteria

3 Years - 19 Years (Child, Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Family with at least one psychiatrically ill parent and at least one child between the age of 3 and 19 years
  • Consent to participate in the study
  • Sufficient knowledge of the German language of parents and children

Exclusion Criteria:

  • Severe psychiatric disorders and impairments with acute symptoms such as suicidal tendencies, massive self-injurious behaviour, acute psychotic symptoms etc., making a stationary treatment inevitable and making a ambulatory intervention appear contraindicated (These patients are placed in stationary treatment)
  • Children with severe symptoms in the control group will be placed at a participating psychotherapist. Nevertheless, they stay in the control group (as TAU).

Sites / Locations

  • Charité Campus Virchow Klinikum, Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters
  • Vitos psychiatrische Ambulanz Eltville
  • Bezirkskrankenhaus Günzburg, Klinik für Psychiatrie, Psychotherapie und Psychosomatik
  • LWL-Klinikum Gütersloh, Klinik für Allgemeine Psychiatrie und Psychotherapie
  • Asklepios Klinikum Harburg
  • Schön Klinik Hamburg Eilbek, Abteilung für Psychiatrie und Psychotherapie
  • University Medical Center Hamburg-Eppendorf, Clinic and Polyclinic for psychiatry and psychotherapy
  • Vitos psychiatrische Ambulanzen Idstein
  • Universitätsklinikum Leipzig, Klinik für Psychiatrie, Psychotherapie und Psychosomatik des Kindes- und Jugendalters
  • Universitätsklinkum Leipzig, Klinik und Poliklinik für Psychiatrie und Psychotherapie
  • LWL-Klinik Paderborn, Allgemeine Psychiatrie und Psychotherapie
  • Klinik für Psychiatrie und Psychotherapie des Sächsischen Krankenhauses Altscherbitz
  • Vitos psychiatrische Tageskliniken Wiesbaden
  • Centre of Social Pediatrics, Dept. of Pediatrics and Adolescent Medicine

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

No Intervention

Arm Label

CHIMPs intervention

Control

Arm Description

Family-Intervention

The long-term effectiveness of the CHIMPs intervention under conditions of practice will be examined in comparison to a control condition receiving the usual after care (Treatment as usual = TAU); this testing of effectiveness will be performed in due consideration of the health economic aspects. The treatment as usual implies that families of the control Group receive the Treatment that is customary in regular care. Thus, these families normally don't receive any post-treatment. If, however, a member of a control group family appears to have an urgent need for treatment (every Family receives a comprehensive diagnostic investigation at the beginning of the study), the respective family will be placed in the ambulatory care system.

Outcomes

Primary Outcome Measures

children's psychiatric symptomatology (Kiddie-SADS interview)
Children's psychiatric symptomatology will be assessed, in both groups (Intervention group and control group), by an external Independent interview (Kiddie-SADS, Kaufman et al., 1996). The Kiddie-SADS interview will be conducted by a trained rater external to the project (observer-blind rater).
children's psychiatric symptomatology (Child behaviour checklist)
The psychiatric disorders of the children will further be assessed by the CBCL ("Child behaviour checklist", Achenbach, 1991),
children's psychiatric symptomatology (assessed by Youth Self Report)
The psychiatric disorders of the children will further be assessed by the YSR ("Youth self Report", Achenbach, 1991)
children's psychiatric symptomatology (assessed by the SGKJ)
The psychiatric disorders of the children will further be assessed by the SGKJ ("Skala zur Gesamtbeurteilung von Kindern und Jugendlichen", a scale for the overall assessment of children and adolescents, Steinhausen, 1985).
children's psychiatric symptomatology (Kiddie-SADS interview)
Children's psychiatric symptomatology will be assessed, in both groups (Intervention group and control group), by an external Independent interview (Kiddie-SADS, Kaufman et al., 1996). The Kiddie-SADS interview will be conducted by a trained rater external to the project (observer-blind rater).
children's psychiatric symptomatology (Kiddie-SADS interview)
Children's psychiatric symptomatology will be assessed, in both groups (Intervention group and control group), by an external Independent interview (Kiddie-SADS, Kaufman et al., 1996). The Kiddie-SADS interview will be conducted by a trained rater external to the project (observer-blind rater).
children's psychiatric symptomatology (Child behaviour checklist)
The psychiatric disorders of the children will further be assessed by the CBCL ("Child behaviour checklist", Achenbach, 1991),
children's psychiatric symptomatology (Child behaviour checklist)
The psychiatric disorders of the children will further be assessed by the CBCL ("Child behaviour checklist", Achenbach, 1991),
children's psychiatric symptomatology (assessed by Youth Self Report)
The psychiatric disorders of the children will further be assessed by the YSR ("Youth self Report", Achenbach, 1991)
children's psychiatric symptomatology (assessed by Youth Self Report)
The psychiatric disorders of the children will further be assessed by the YSR ("Youth self Report", Achenbach, 1991)
children's psychiatric symptomatology (assessed by the SGKJ)
The psychiatric disorders of the children will further be assessed by the SGKJ ("Skala zur Gesamtbeurteilung von Kindern und Jugendlichen", a scale for the overall assessment of children and adolescents, Steinhausen, 1985).
children's psychiatric symptomatology (assessed by the SGKJ)
The psychiatric disorders of the children will further be assessed by the SGKJ ("Skala zur Gesamtbeurteilung von Kindern und Jugendlichen", a scale for the overall assessment of children and adolescents, Steinhausen, 1985).

Secondary Outcome Measures

children's health related quality of life (Kidscreen)
Kidscreen (Ravens-Sieberer et al., 2006)
parents' health related quality of life (EQ-5D)
EQ-5D (Brooks, Rabon & de Charro, 2003; Hinz, Klaiberg, Brähler & König, 2006)
Symptomatology of the parents (Brief Symptom Inventory)
Brief Symptom Inventory (Franke, 2000)
Symptomatology of the parents (only Intervention group) (SKID; a structured clinical interview for DSM-IV)
Strukturiertes Klinisches Interview für DSM-IV (SKID; a structured clinical interview for DSM-IV, Wittchen, Zaudig & Fydrich, 1997)
parents' coping with the disorder (Freiburger Fragebogen zur Krankheitsbewältigung)
Freiburger Fragebogen zur Krankheitsbewältigung (FKV; Muthny, 1989)
family relations (children and parents) (Allgemeiner Familienfragebogen)
Allgemeiner Familienfragebogen (FB-A;Cierpka & Frevert, 1995)
Social Support (Oslo Social Support Questionnaire)
Oslo Social Support Questionnaire (OSSQ; Dalgaard, 1996)
Objectives of the treatment (children and parents)
Objective of the treatment, assessed by the item "What could be the main objective of a possible treatment?"
achievement of the objectives of the treatment (children and parents)
achievement of the objectives of the treatment, assessed by the item "Did you achieve the main objective of your treatment?" and by the item "Taken as a whole, did the family sessions help you?"
Evaluation of the Treatment (children and parents) (Fragebogen zur Beurteilung der Behandlung)
Fragebogen zur Beurteilung der Behandlung (FBB; Mattejat & Remschmidt, 1999)
health economic assessment of treatment costs (children) (German version of the "Children and adolescent mental health Services receipt inventory)
German version of the Children and adolescent mental health Services receipt inventory" (CAMHSRI; Kilian et al., 2009)
health economic assessment of treatment costs (parents) (German version of the Client Socioeconomic and Services Receipt Inventory)
German version of the "Client Socioeconomic and Services Receipt Inventory" (CSSRI; Roick et al., 2001)
Symptomatology of the parents
German version of the "Patient Health Questionnaire" (PHQ; Löwe, Spitzer, Zipfel & Herzog, 2002)

Full Information

First Posted
November 26, 2014
Last Updated
July 16, 2020
Sponsor
Silke Wiegand-Grefe, Prof. Dr.
Collaborators
Universitätsklinikum Hamburg-Eppendorf, University of Ulm, Universitätsklinikum Leipzig, LWL-Klinikum Gütersloh, Vitos Klinik Rheinhöhe, Charite University, Berlin, Germany, Cantonal Hospital Winterthur, Switzerland
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1. Study Identification

Unique Protocol Identification Number
NCT02308462
Brief Title
Implementation and Evaluation of a Family-based Intervention Program for Children of Mentally Ill Parents
Acronym
CHIMPs
Official Title
Implementation and Evaluation of a Family-based Intervention Program for Children and Adolescents of Mentally Ill Parents - a Randomized Controlled Multicenter Trial
Study Type
Interventional

2. Study Status

Record Verification Date
July 2020
Overall Recruitment Status
Completed
Study Start Date
November 2014 (undefined)
Primary Completion Date
June 2019 (Actual)
Study Completion Date
June 2019 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor-Investigator
Name of the Sponsor
Silke Wiegand-Grefe, Prof. Dr.
Collaborators
Universitätsklinikum Hamburg-Eppendorf, University of Ulm, Universitätsklinikum Leipzig, LWL-Klinikum Gütersloh, Vitos Klinik Rheinhöhe, Charite University, Berlin, Germany, Cantonal Hospital Winterthur, Switzerland

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
In order to identify psychological stress in children and adolescents of mentally ill parents as early as possible, a special intervention program (CHIMPs = Children of mentally ill parents) was developed. The study at hand will implement this intervention program at five sites in Germany and will further evaluate its effectiveness. The CHIMPs intervention is assumed to reduce children's psychopathology and enhance their health related quality of life.
Detailed Description
The main purpose of this study is to implement the manualized family intervention CHIMPs (Children of mentally ill parents) for children and adolescents of psychiatrically ill parents aged between 3 and 19 years at the seven participating centres in regular care. The intervention aims at reducing children's psychopathology and enhancing their quality of life in a sustainable way and, moreover, aims at introducing especially remarkable children and adolescents to an early intervention. The study represents a prospective, randomized and controlled multicenter study (RCT), contrasting one intervention group and one control group (TAU = Treatment as usual) by measurements at baseline and after six, 12 and 18 months. Within the data collection, the perspective of the psychiatrically ill parent, the partner, each child and the therapist will be considered. Children between 3 and 9 years of age will be evaluated only by the parents and the therapist, from 10 years on, an additional self-report form will be filled out by the child. The measurement will be ruled out indirectly (for the pre-post-measurement) as well as directly (at the end of treatment). For each endpoint, one comprehensive mixed model will be fitted to the data containing the baseline value and further relevant patient characteristics as covariates, the random group as factor and cluster (center, therapy group, family) as random effect. Missing values will be treated by direct imputation to allow an intention-to-treat analysis.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Schizophrenia and Disorders With Psychotic Features, Mood Disorders, Neurotic Disorders, Personality Disorders, Substance-Related Disorders
Keywords
children of mentally ill parents, family intervention, randomized controlled trial

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
400 (Actual)

8. Arms, Groups, and Interventions

Arm Title
CHIMPs intervention
Arm Type
Experimental
Arm Description
Family-Intervention
Arm Title
Control
Arm Type
No Intervention
Arm Description
The long-term effectiveness of the CHIMPs intervention under conditions of practice will be examined in comparison to a control condition receiving the usual after care (Treatment as usual = TAU); this testing of effectiveness will be performed in due consideration of the health economic aspects. The treatment as usual implies that families of the control Group receive the Treatment that is customary in regular care. Thus, these families normally don't receive any post-treatment. If, however, a member of a control group family appears to have an urgent need for treatment (every Family receives a comprehensive diagnostic investigation at the beginning of the study), the respective family will be placed in the ambulatory care system.
Intervention Type
Behavioral
Intervention Name(s)
CHIMPS intervention
Intervention Description
CHIMPs intervention (Family-Intervention composed of 8 Topic-related sessions over a period of 6 month, based on the evaluated manual: a preliminary talk with the family, two sessions with the parents, one session with each child, three sessions with the family). The sessions are semi-structured and cover the topics illness and coping, education, family relationships and trusting attachement figures, social network and support of the Family. A detailed description of the procedure is found in the Manual (Wiegand-Grefe, Halverscheid & Plass, 2011).
Primary Outcome Measure Information:
Title
children's psychiatric symptomatology (Kiddie-SADS interview)
Description
Children's psychiatric symptomatology will be assessed, in both groups (Intervention group and control group), by an external Independent interview (Kiddie-SADS, Kaufman et al., 1996). The Kiddie-SADS interview will be conducted by a trained rater external to the project (observer-blind rater).
Time Frame
at the beginning of the study (on study enrolment)
Title
children's psychiatric symptomatology (Child behaviour checklist)
Description
The psychiatric disorders of the children will further be assessed by the CBCL ("Child behaviour checklist", Achenbach, 1991),
Time Frame
at the beginning of the study (on study enrolment)
Title
children's psychiatric symptomatology (assessed by Youth Self Report)
Description
The psychiatric disorders of the children will further be assessed by the YSR ("Youth self Report", Achenbach, 1991)
Time Frame
at the beginning of the study (on study enrolment)
Title
children's psychiatric symptomatology (assessed by the SGKJ)
Description
The psychiatric disorders of the children will further be assessed by the SGKJ ("Skala zur Gesamtbeurteilung von Kindern und Jugendlichen", a scale for the overall assessment of children and adolescents, Steinhausen, 1985).
Time Frame
at the beginning of the study (on study enrolment)
Title
children's psychiatric symptomatology (Kiddie-SADS interview)
Description
Children's psychiatric symptomatology will be assessed, in both groups (Intervention group and control group), by an external Independent interview (Kiddie-SADS, Kaufman et al., 1996). The Kiddie-SADS interview will be conducted by a trained rater external to the project (observer-blind rater).
Time Frame
after the treatment (after 6 months)
Title
children's psychiatric symptomatology (Kiddie-SADS interview)
Description
Children's psychiatric symptomatology will be assessed, in both groups (Intervention group and control group), by an external Independent interview (Kiddie-SADS, Kaufman et al., 1996). The Kiddie-SADS interview will be conducted by a trained rater external to the project (observer-blind rater).
Time Frame
after the follow-up period (after 18 months)
Title
children's psychiatric symptomatology (Child behaviour checklist)
Description
The psychiatric disorders of the children will further be assessed by the CBCL ("Child behaviour checklist", Achenbach, 1991),
Time Frame
after the treatment (after 6 months)
Title
children's psychiatric symptomatology (Child behaviour checklist)
Description
The psychiatric disorders of the children will further be assessed by the CBCL ("Child behaviour checklist", Achenbach, 1991),
Time Frame
after the follow-up period (after 18 months)
Title
children's psychiatric symptomatology (assessed by Youth Self Report)
Description
The psychiatric disorders of the children will further be assessed by the YSR ("Youth self Report", Achenbach, 1991)
Time Frame
after the treatment (after 6 months)
Title
children's psychiatric symptomatology (assessed by Youth Self Report)
Description
The psychiatric disorders of the children will further be assessed by the YSR ("Youth self Report", Achenbach, 1991)
Time Frame
after the follow-up period (after 18 months)
Title
children's psychiatric symptomatology (assessed by the SGKJ)
Description
The psychiatric disorders of the children will further be assessed by the SGKJ ("Skala zur Gesamtbeurteilung von Kindern und Jugendlichen", a scale for the overall assessment of children and adolescents, Steinhausen, 1985).
Time Frame
after the treatment (after 6 months)
Title
children's psychiatric symptomatology (assessed by the SGKJ)
Description
The psychiatric disorders of the children will further be assessed by the SGKJ ("Skala zur Gesamtbeurteilung von Kindern und Jugendlichen", a scale for the overall assessment of children and adolescents, Steinhausen, 1985).
Time Frame
after the follow-up period (after 18 months)
Secondary Outcome Measure Information:
Title
children's health related quality of life (Kidscreen)
Description
Kidscreen (Ravens-Sieberer et al., 2006)
Time Frame
at the beginning (on study enrolment) and at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
parents' health related quality of life (EQ-5D)
Description
EQ-5D (Brooks, Rabon & de Charro, 2003; Hinz, Klaiberg, Brähler & König, 2006)
Time Frame
at the beginning (on study enrolment) and at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
Symptomatology of the parents (Brief Symptom Inventory)
Description
Brief Symptom Inventory (Franke, 2000)
Time Frame
at the beginning (on study enrolment) and at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
Symptomatology of the parents (only Intervention group) (SKID; a structured clinical interview for DSM-IV)
Description
Strukturiertes Klinisches Interview für DSM-IV (SKID; a structured clinical interview for DSM-IV, Wittchen, Zaudig & Fydrich, 1997)
Time Frame
during CHIMPs intervention
Title
parents' coping with the disorder (Freiburger Fragebogen zur Krankheitsbewältigung)
Description
Freiburger Fragebogen zur Krankheitsbewältigung (FKV; Muthny, 1989)
Time Frame
at the beginning (on study enrolment) and at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
family relations (children and parents) (Allgemeiner Familienfragebogen)
Description
Allgemeiner Familienfragebogen (FB-A;Cierpka & Frevert, 1995)
Time Frame
at the beginning (on study enrolment) and at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
Social Support (Oslo Social Support Questionnaire)
Description
Oslo Social Support Questionnaire (OSSQ; Dalgaard, 1996)
Time Frame
at the beginning (on study enrolment) and at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
Objectives of the treatment (children and parents)
Description
Objective of the treatment, assessed by the item "What could be the main objective of a possible treatment?"
Time Frame
at the beginning of the study (on study enrolment)
Title
achievement of the objectives of the treatment (children and parents)
Description
achievement of the objectives of the treatment, assessed by the item "Did you achieve the main objective of your treatment?" and by the item "Taken as a whole, did the family sessions help you?"
Time Frame
at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
Evaluation of the Treatment (children and parents) (Fragebogen zur Beurteilung der Behandlung)
Description
Fragebogen zur Beurteilung der Behandlung (FBB; Mattejat & Remschmidt, 1999)
Time Frame
at the end of the intervention (after 6 months) as well as after the follow-up period (after 18 months)
Title
health economic assessment of treatment costs (children) (German version of the "Children and adolescent mental health Services receipt inventory)
Description
German version of the Children and adolescent mental health Services receipt inventory" (CAMHSRI; Kilian et al., 2009)
Time Frame
at the beginning (on study enrolment), at the end of treatment (after 6 months), after 12 months and after the follow-up period (after 18 months)
Title
health economic assessment of treatment costs (parents) (German version of the Client Socioeconomic and Services Receipt Inventory)
Description
German version of the "Client Socioeconomic and Services Receipt Inventory" (CSSRI; Roick et al., 2001)
Time Frame
at the beginning (on study enrolment), at the end of treatment (after 6 months), after 12 months and after the follow-up period (after 18 months)
Title
Symptomatology of the parents
Description
German version of the "Patient Health Questionnaire" (PHQ; Löwe, Spitzer, Zipfel & Herzog, 2002)
Time Frame
at the beginning (on study enrolment)

10. Eligibility

Sex
All
Minimum Age & Unit of Time
3 Years
Maximum Age & Unit of Time
19 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Family with at least one psychiatrically ill parent and at least one child between the age of 3 and 19 years Consent to participate in the study Sufficient knowledge of the German language of parents and children Exclusion Criteria: Severe psychiatric disorders and impairments with acute symptoms such as suicidal tendencies, massive self-injurious behaviour, acute psychotic symptoms etc., making a stationary treatment inevitable and making a ambulatory intervention appear contraindicated (These patients are placed in stationary treatment) Children with severe symptoms in the control group will be placed at a participating psychotherapist. Nevertheless, they stay in the control group (as TAU).
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Silke Wiegand-Grefe, Prof.
Organizational Affiliation
Universitätsklinikum Hamburg-Eppendorf
Official's Role
Principal Investigator
Facility Information:
Facility Name
Charité Campus Virchow Klinikum, Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters
City
Berlin
Country
Germany
Facility Name
Vitos psychiatrische Ambulanz Eltville
City
Eltville
Country
Germany
Facility Name
Bezirkskrankenhaus Günzburg, Klinik für Psychiatrie, Psychotherapie und Psychosomatik
City
Günzburg
Country
Germany
Facility Name
LWL-Klinikum Gütersloh, Klinik für Allgemeine Psychiatrie und Psychotherapie
City
Gütersloh
Country
Germany
Facility Name
Asklepios Klinikum Harburg
City
Hamburg-Harburg
Country
Germany
Facility Name
Schön Klinik Hamburg Eilbek, Abteilung für Psychiatrie und Psychotherapie
City
Hamburg
Country
Germany
Facility Name
University Medical Center Hamburg-Eppendorf, Clinic and Polyclinic for psychiatry and psychotherapy
City
Hamburg
Country
Germany
Facility Name
Vitos psychiatrische Ambulanzen Idstein
City
Idstein
Country
Germany
Facility Name
Universitätsklinikum Leipzig, Klinik für Psychiatrie, Psychotherapie und Psychosomatik des Kindes- und Jugendalters
City
Leipzig
Country
Germany
Facility Name
Universitätsklinkum Leipzig, Klinik und Poliklinik für Psychiatrie und Psychotherapie
City
Leipzig
Country
Germany
Facility Name
LWL-Klinik Paderborn, Allgemeine Psychiatrie und Psychotherapie
City
Paderborn
Country
Germany
Facility Name
Klinik für Psychiatrie und Psychotherapie des Sächsischen Krankenhauses Altscherbitz
City
Schkeuditz
Country
Germany
Facility Name
Vitos psychiatrische Tageskliniken Wiesbaden
City
Wiesbaden
Country
Germany
Facility Name
Centre of Social Pediatrics, Dept. of Pediatrics and Adolescent Medicine
City
Winterthur
Country
Switzerland

12. IPD Sharing Statement

Plan to Share IPD
Undecided
Citations:
PubMed Identifier
18924530
Citation
Krohn L, Deneke C, Wiegand-Grefe S. [Children of depressive parents and psychiatrically inconspicuous parents in the child and adolescent psychiatry--a comparison study]. Prax Kinderpsychol Kinderpsychiatr. 2008;57(7):536-54. doi: 10.13109/prkk.2008.57.7.536. German.
Results Reference
background
PubMed Identifier
18575057
Citation
Pollak E, Bullinger M, Jeske J, Wiegand-Grefe S. [How do mentally ill parents evaluate their children's quality of life? Associations with the parent's illness and family functioning]. Prax Kinderpsychol Kinderpsychiatr. 2008;57(4):301-14. doi: 10.13109/prkk.2008.57.4.301. German.
Results Reference
background
PubMed Identifier
18815965
Citation
Pollak E, Wiegand-Grefe S, Hoger D. The Bielefeld attachment questionnaires: overview and empirical results of an alternative approach to assess attachment. Psychother Res. 2008 Mar;18(2):179-90. doi: 10.1080/10503300701376365.
Results Reference
background
PubMed Identifier
21089005
Citation
Wiegand-Grefe S, Geers P, Petermann F, Plass A. [Children of mentally ill parents: the impact of parental psychiatric diagnosis, comorbidity, severity and chronicity on the well-being of children]. Fortschr Neurol Psychiatr. 2011 Jan;79(1):32-40. doi: 10.1055/s-0029-1245623. Epub 2010 Nov 18. German.
Results Reference
background
Citation
Jeske J, Bullinger M, Wiegand-Grefe S. Do attachement Patterns of parents with a mental illness have an Impact upon how they view the Quality of life of their children? Vulnerable Children and Youth Studies 6(1): 39-50, 2011.
Results Reference
background
Citation
Wiegand-Grefe S, Werkmeister S, Bullinger M, Plass A, Petermann F. [Health-related quality of life and social support of children with mentally ill parents: Effects of a manualized family intervention]. Kindheit und Entwicklung 21 (1): 64-73, 2012.
Results Reference
background
Citation
Jeske J, Bullinger M, Plass A, Petermann F, Wiegand-Grefe S. [Risk factor coping with a disease: Associations between coping an health related quality of life of children with a mentally ill parent]. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie 57 (3): 207-213, 2009.
Results Reference
background
Citation
Jeske J, Bullinger M, Wiegand-Grefe S. [Families with mentally ill parents - Connections between Family functioning and health-related life quality of children]. Familiendynamik 35 (4): 338-347, 2010.
Results Reference
background
Citation
Wiegand-Grefe S, Halverscheid S, Geers P, Petermann F, Plass A. [Children of mentally ill parents: The relationship between coping with a parental mental illness and children's mental health]. Zeitschrift für Klinische Psychologie und Psychotherapie 39 (1): 13-23, 2010.
Results Reference
background
Citation
Wiegand-Grefe S, Jeske J, Bullinger M, Plass A, Petermann F. [Quality of life of children with psychiatrically ill parents: Relationship between characteristics of parental disorder and health-related quality of life of the children estimated by the parents]. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie 58 (4): 315-322, 2010.
Results Reference
background
Citation
Wiegand-Grefe S, Cronemeyer B, Plass A, Schulte-Markwort M, Petermann F. [Comparison of mental abnormalities in children of mentally ill parents from different points of view: Effects of a manualized family intervention]. Kindheit und Entwicklung 22 (1): 31-40, 2013.
Results Reference
background
Citation
Wiegand-Grefe S, Cronemeyer B, Halverscheid S, Redlich A, Petermann F. [Coping strategies of psychiatrically ill parents and psychological abnormalities of their children through the focus of a manualized family intervention]. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie 61 (1): 51-58, 2013.
Results Reference
background
PubMed Identifier
33551858
Citation
Wiegand-Grefe S, Filter B, Busmann M, Kilian R, Kronmuller KT, Lambert M, Norra C, von Klitzing K, Albermann K, Winter SM, Daubmann A, Wegscheider K, Plass-Christl A. Evaluation of a Family-Based Intervention Program for Children of Mentally Ill Parents: Study Protocol for a Randomized Controlled Multicenter Trial. Front Psychiatry. 2021 Jan 20;11:561790. doi: 10.3389/fpsyt.2020.561790. eCollection 2020.
Results Reference
derived

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Implementation and Evaluation of a Family-based Intervention Program for Children of Mentally Ill Parents

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