Improving Implementation of Evidence-based Approaches and Surveillance to Prevent Bacterial Transmission and Infection (BASIC)
Infection
About this trial
This is an interventional prevention trial for Infection focused on measuring transmission, ESKAPE, prevention
Eligibility Criteria
Site Inclusion and Exclusion Criteria.
- 250 patients (125 case pairs) per site in the active phase (N=3,000)
- 250 patients (125 case pairs) per site in the sustainability phase (N=3,000)
- Total N=6,000
- orthopedic total joint and spine procedures
Site Inclusion Criteria:
- operating room conducting orthopedic total joint and spine
- Surgeons performing orthopedic total joint or spine
Site Exclusion Criteria:
- medical centers actively enrolling patients in a bacterial transmission or infection prevention trial
Patient Inclusion Criteria:
- all elective patients undergoing orthopedic total joint and spine
Exclusion Criteria:
- no requirement for anesthesia and/or placement of a peripheral intravenous catheter
- lack of incision or informed, written consent
- an allergy to chlorhexidine
- povidone iodine or isopropyl alcohol
- ASA health classification status>5
Sites / Locations
- University of IowaRecruiting
- Trustees of Dartmouth CollegeRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Surveillance with Technical Assistance
Surveillance with EBIP Coaching
Technical Assistance No Surveillance
EBIP Coaching No Surveillance
Surveillance will be offered to 3 teams with Technical Assistance (TA) in block randomization. Surveillance tool will execute regularly updated reports (continually updated with laboratory data entry of ESKAPE pathogen isolation results), which generates a set of data that will populate series of tables and graphs for each site based on data collection form as previously reported.
Surveillance will be offered to 3 teams with Evidence-Based Infection Prevention Bundle (EBIP) coaching in block randomization. Surveillance tool will execute regularly updated reports (continually updated with laboratory data entry of ESKAPE pathogen isolation results), which generates a set of data that will populate series of tables and graphs for each site based on data collection form as previously reported. EBIP involves evidence-based improvements in perioperative hand hygiene, environmental cleaning, vascular care, and patient decolonization. Each participating site will receive monthly team-based coaching to establish a multidisciplinary team charged with continuously improving transmission and infection prevention.
TA will be offered to 3 teams. TA will have monthly scheduled TA calls (60 minutes each) with each team individually to review and discuss the protocol interventions (as is done in the EBIP group) and allow for a consultation with experts on the peri-operative interventions. Surveillance toolkit will only be used for transmission data collection.
EBIP will be offered to 3 teams. Each participating site will receive monthly team-based coaching to establish a multidisciplinary team charged with continuously improving transmission and infection prevention. EBIP involves evidence-based improvements in perioperative hand hygiene, environmental cleaning, vascular care, and patient decolonization. Surveillance toolkit will only be used for transmission data collection.