Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn
About this trial
This is an interventional treatment trial for Epidural focused on measuring Epidural, Opioids, Fentanyl, Labour Induction, Labour Pain, Obstetric Pain, Induction of Labour, Anesthesia, Obstetric Anesthesia
Eligibility Criteria
Inclusion Criteria:
- Healthy parturients
- Parturients presenting for labour induction for post-term pregnancy (i.e. pregnancy beyond 42 weeks gestational age)
- Parturients who have had an uncomplicated pregnancy
Exclusion Criteria:
- Parturients presenting for induction of labour for pre-labour (premature) rupture of membranes
- Parturients presenting for induction of labour for hypertensive disorders of pregnancy [including preeclampsia, eclampsia, HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets)]
- Parturients with maternal diabetes
- Fetal growth restriction
- Multiple gestation pregnancy
- Known or suspected Chorioamnionitis
- Known or suspected Abruptio placentae
- Oligohydramnios
- Parturients with cholestasis of pregnancy
- Known alloimmunization with fetal effects.
- Parturients with other chronic medical conditions or any complications related to pregnancy
- Participants who lack capacity to consent on their own behalf
Sites / Locations
- Royal University Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Control Group (No Additional Epidural Fentanyl Bolus)
Fentanyl bolus group
The Control group will receive a 2 ml bolus of standard epidural mix solution after epidural placement followed by standard care infusion of epidural local anesthetic/opioids, with a PCEA pump for subsequent analgesia.
The Fentanyl bolus group will receive a 2 ml bolus of epidural Fentanyl (50 mcg/ml; therefore a total dose of 100 mcg) after epidural placement, followed by a standard care infusion of epidural local anesthetic/opioids, with a PCEA pump for subsequent analgesia.