Individualization of Nutritive Sensory Support Of Radiation Therapy
Radiotherapy; Complications, Head and Neck Cancer
About this trial
This is an interventional supportive care trial for Radiotherapy; Complications focused on measuring Nutritional support, Radiotherapy, Head and Neck Cancer, Complications
Eligibility Criteria
Inclusion Criteria:
- Age> 18 years
- The presence of morphological verification of squamous cell carcinoma of the head and neck
- No history of anticancer treatment
- ECOG score 0 - 2
- Life expectancy is more than 3 months
- Normal liver, kidney and bone marrow function
- Absence of severe uncontrolled concomitant chronic diseases and acute diseases (including infectious diseases)
- Absence of pregnancy, lactation
- Initial compliance of patients (according to the consultation of a psychologist and questionnaires) with a signed informed consent
Exclusion Criteria:
- Simultaneous participation in another clinical trial
- Failure to meet inclusion criteria
- The patient's condition is ECOG ≥3, Karnovsky ≤40%.
- Bleeding
- Decay / Abscess in the area of tumor lesion
- Pregnancy or breastfeeding
- Refractory cachexia
- Allergy or intolerance to any of the components of ONS
Sites / Locations
- P. Hertsen Moscow Oncology Research Institute
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Sham Comparator
Test
Prospective Control group
Retrospective Control group
50 patients with squamous cell head cancer over 18 years of age, receiving chemoradiation therapy, receiving 3 bottles (х 200 ml) of ONS with Protein Oncosensation with a neutral taste throughout the course of treatment.
50 patients over 18 years of age with squamous cell carcinoma of the head and neck, receiving chemoradiation therapy, receiving standard nutritional therapy with a neutral taste throughout the course of treatment.
60 patients who received chemoradiotherapy earlier with standard nutritional support.