Indocyanine Green to Visualize Critical View of Safety During Laparoscopic Cholecystectomy for Acute Cholecystitis
Acute Cholecystitis, Acute; Cholecystitis, Choledocholithiasis, Acute Cholecystitis With Obstruction
About this trial
This is an interventional diagnostic trial for Acute Cholecystitis focused on measuring acute cholecystitis, laparoscopic cholecystectomy, critical view of safety, safe cholecystectomy, indocyanine green, operative cholangiogram, fluorescent imaging, near-infrared imaging
Eligibility Criteria
Inclusion Criteria:
- Patient scheduled for emergency Laparoscopic Cholecystectomy for Acute Cholecystitis
- Patient age ≥ 18 years.
- Patients who consent to take part in the study
Exclusion Criteria:
- Preoperative planned for Open Cholecystectomy
- Allergy towards iodine, iohexol or ICG
- Pregnancy or lactation
- Renal insufficiency
- Legally incompetent for any reason
- Withdrawal of inclusion consent at any time
- Prisoners
Sites / Locations
- Hamad General Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
ICG group
No ICG Group
Participants receive an intravenous injection of 0.05 mg/kg of ICG 45 minutes preoperatively. A Pinpoint Endoscopic Fluorescence System (Novadac Technologies Inc., Canada) for ICG Fluorescence Observation with the easy switchable white light-fluorescent mode is used. Before dividing any tubular structure, the fluorescence imaging mode is routinely used again, and fluorescent angiography is performed by re-injecting the same dose of ICG as initially used. After the division of the cystic duct and artery, the fluorescence imaging mode is applied again to check for bile leakage.
No ICG is administered after randomization of the patient to a control group and hence will not produce any enhancement of the image on A Pinpoint Endoscopic Fluorescence System for ICG Fluorescence Observation. This will continue as a routine Laparoscopic cholecystectomy without fluorescent imaging enhancement.