Inflammatory Abnormalities in Muscle After Stroke: Effects of Exercise
Stroke, Inflammation
About this trial
This is an interventional treatment trial for Stroke focused on measuring exercise, inflammation, motor performance, skeletal muscle, chronic stroke survivors, treadmill exercise
Eligibility Criteria
Inclusion Criteria:
- Chronic stroke (>6 months after initial stroke)
- Age 40-80
- Stable neurologic deficits
- Able to walk with an assistive device
- Language skills to understand the training program safely
Exclusion Criteria:
- No anticoagulation or medical conditions that preclude exercise.
- No dementias or depression
Sites / Locations
- VA Maryland Health Care System, Baltimore
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Velocity based treadmill training
Duration based treadmill training
6 month of progressive treadmill walking with treadmill speed gradually progressed to meet the training heart rate goals for moderate intensity aerobic exercise, when hemiparetic gait velocity can no longer be safely progressed, incline is added to achieve the heart rate training goals.
6 month of progressive treadmill walking with duration is gradually progressed to meet the endurance goals for low aerobic intensity exercise, gait velocity and incline do not progress.