Influencing Factors of Intracranial Hypertension in Patients With Bilateral Transverse Sinus Stenosis
Vertebral Venous Collaterals, Serum Uric Acid, Intracranial Hypertension
About this trial
This is an interventional diagnostic trial for Vertebral Venous Collaterals focused on measuring vertebral venous collaterals, serum uric acid, Bilateral transverse sinus stenosis, intracranial hypertension
Eligibility Criteria
Inclusion Criteria:
- BTSS confirmed by two of magnetic resonance venography (MRV), computed tomography venography (CTV) or digital subtraction angiography (DSA).
Exclusion Criteria:
- medicine related intracranial hypertension;
- systemic inflammation;
- moderate to severe stenosis in intracranial, carotid or vertebral arteries;
- moderate to severe stenosis in intracranial or jugular veins other than transverse sinus;
- intracranial lesions.
Sites / Locations
- Xuanwu Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Sham Comparator
Sham Comparator
Active Comparator
Active Comparator
normal controls with VVC
normal controls without VVC
BTSS patients with VVC
BTSS patients without VVC
BTSS was confirmed by two of magnetic resonance venography (MRV), computed tomography venography (CTV) or digital subtraction angiography (DSA). The index of TSS (ITSS) score was a useful tool for the assessment of BTSS severity. The degree of stenosis was graded from 0 to 4 based on the following scale: 0 = normal; 1 = stenosis up to 1/3; 2 = stenosis between 1/3 and 2/3; 3 = stenosis >2/3; and 4 = hypoplasia. ITSS was calculated as degree of right TSS × degree of left TSS. Vertebral venous collaterals (VVC) were found.
BTSS was confirmed by two of magnetic resonance venography (MRV), computed tomography venography (CTV) or digital subtraction angiography (DSA). The index of TSS (ITSS) score was a useful tool for the assessment of BTSS severity. The degree of stenosis was graded from 0 to 4 based on the following scale: 0 = normal; 1 = stenosis up to 1/3; 2 = stenosis between 1/3 and 2/3; 3 = stenosis >2/3; and 4 = hypoplasia. ITSS was calculated as degree of right TSS × degree of left TSS. Vertebral venous collaterals (VVC) were not found.
BTSS was confirmed by two of magnetic resonance venography (MRV), computed tomography venography (CTV) or digital subtraction angiography (DSA). The index of TSS (ITSS) score was a useful tool for the assessment of BTSS severity. The degree of stenosis was graded from 0 to 4 based on the following scale: 0 = normal; 1 = stenosis up to 1/3; 2 = stenosis between 1/3 and 2/3; 3 = stenosis >2/3; and 4 = hypoplasia. ITSS was calculated as degree of right TSS × degree of left TSS. Vertebral venous collaterals (VVC) were found.
BTSS was confirmed by two of magnetic resonance venography (MRV), computed tomography venography (CTV) or digital subtraction angiography (DSA). The index of TSS (ITSS) score was a useful tool for the assessment of BTSS severity. The degree of stenosis was graded from 0 to 4 based on the following scale: 0 = normal; 1 = stenosis up to 1/3; 2 = stenosis between 1/3 and 2/3; 3 = stenosis >2/3; and 4 = hypoplasia. ITSS was calculated as degree of right TSS × degree of left TSS. Vertebral venous collaterals (VVC) were not found.