search
Back to results

Interactive Motor Imagery in Virtual Reality

Primary Purpose

Spinal Cord Injury, Stroke

Status
Completed
Phase
Not Applicable
Locations
Switzerland
Study Type
Interventional
Intervention
iCTuS-L
Sponsored by
University of Zurich
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Spinal Cord Injury

Eligibility Criteria

16 Years - 80 Years (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Age between 16 and 80
  • clinically incomplete spinal cord injury (time since injury: chronic > 1 year; acute < 3 months)
  • ASI C or D
  • neuropathic pain and/or motor deficits
  • diagnosed neurological disorder, eg. stroke

Exclusion Criteria:

  • any disease limiting training
  • epilepsy
  • major depression or psychosis

Sites / Locations

  • Curt, Armin, MD

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Rehabilitation

Arm Description

Outcomes

Primary Outcome Measures

Sensorimotor Assessment
Questionnaire assessing distinct pain qualities associated with neuropathic pain, structured pain interview, questionnaire for assessing patients diagnosed as depressed and detects depression among the normal population, transcutaneous electrical stimulation of superficial nerves, information about the motor level of the lesion, the sensory levels of the lesion (light touch and pin prick), questionnaire assessing activities of daily life and independence in subjects with spinal cord lesion, walking aids and/or personal assistance, examining gait speed, transcranial magnetic stimulation

Secondary Outcome Measures

Full Information

First Posted
April 24, 2014
Last Updated
January 6, 2020
Sponsor
University of Zurich
search

1. Study Identification

Unique Protocol Identification Number
NCT02149186
Brief Title
Interactive Motor Imagery in Virtual Reality
Study Type
Interventional

2. Study Status

Record Verification Date
December 2019
Overall Recruitment Status
Completed
Study Start Date
October 2009 (Actual)
Primary Completion Date
December 2019 (Actual)
Study Completion Date
December 2019 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University of Zurich

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This project will build and test the first rehabilitation system employing virtual reality (VR)-based observation, motor imagery and execution to treat lower-limb neuropathic pain and motor dysfunction in participants with an incomplete spinal cord injury or another neurological disorder, eg. stroke: iCTuS-L (Interactive Computer-based Therapy System for legs). Patients using the system will control virtual representations of their legs to engage in entertaining gaming interactions.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Spinal Cord Injury, Stroke

7. Study Design

Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
79 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Rehabilitation
Arm Type
Experimental
Intervention Type
Device
Intervention Name(s)
iCTuS-L
Primary Outcome Measure Information:
Title
Sensorimotor Assessment
Description
Questionnaire assessing distinct pain qualities associated with neuropathic pain, structured pain interview, questionnaire for assessing patients diagnosed as depressed and detects depression among the normal population, transcutaneous electrical stimulation of superficial nerves, information about the motor level of the lesion, the sensory levels of the lesion (light touch and pin prick), questionnaire assessing activities of daily life and independence in subjects with spinal cord lesion, walking aids and/or personal assistance, examining gait speed, transcranial magnetic stimulation
Time Frame
16 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
16 Years
Maximum Age & Unit of Time
80 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Age between 16 and 80 clinically incomplete spinal cord injury (time since injury: chronic > 1 year; acute < 3 months) ASI C or D neuropathic pain and/or motor deficits diagnosed neurological disorder, eg. stroke Exclusion Criteria: any disease limiting training epilepsy major depression or psychosis
Facility Information:
Facility Name
Curt, Armin, MD
City
Zurich
ZIP/Postal Code
8008
Country
Switzerland

12. IPD Sharing Statement

Citations:
PubMed Identifier
29234302
Citation
Villiger M, Liviero J, Awai L, Stoop R, Pyk P, Clijsen R, Curt A, Eng K, Bolliger M. Home-Based Virtual Reality-Augmented Training Improves Lower Limb Muscle Strength, Balance, and Functional Mobility following Chronic Incomplete Spinal Cord Injury. Front Neurol. 2017 Nov 28;8:635. doi: 10.3389/fneur.2017.00635. eCollection 2017.
Results Reference
derived

Learn more about this trial

Interactive Motor Imagery in Virtual Reality

We'll reach out to this number within 24 hrs