Intradialytic Progressive Resistance Training for Maintenance Haemodialysis Patients (PRT)
Chronic Kidney Disease
About this trial
This is an interventional treatment trial for Chronic Kidney Disease focused on measuring Progressive Resistance Training/Exercise, Muscle wasting, Chronic Kidney Disease
Eligibility Criteria
Inclusion Criteria:
- Chronic kidney diseases stage five requiring maintenance hemodialysis.
Exclusion Criteria:
- Patients who have been receiving dialysis for less than 3 months;
- Are under the age of 18years;
- Have medical contradictions to participate in the exercise programs;
- Any uncontrolled medical condition which does not allow participation in exercise;
- Have known neuro-muscular disorders;
- Have any other uncontrolled medical condition, including pregnancy;
- Are not independently ambulant for 50 m;
- Have received anabolic intervention, or had catabolic conditions within the last 3 months;
- Have a cardiac pacemaker or other unsuitable implanted device for magnetic resonance;
- Are vulnerable to heat stress;
- Or are unable to give consent.
Sites / Locations
- Renal unit, Ysbyty Gwynedd, North West Wales NHS Trust
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Sham Comparator
Experimental
Sham Comparator
Chronic kidney disease progressive resistance training group
Chronic kidney disease sham exercise group
Healthy controls progressive resistance training group
Healthy controls sham exercise group
Progressive resistance training programme using a dialysis specific fitness machine: 80 % of predicted one repetition max, weight lifted will be increased when three sets of ten repetitions can be completed without failure.
Lower body stretching exercise using the easiest rehabilitation elastic Theraband
Progressive resistance training programme using a dialysis specific fitness machine: 80 % of predicted one repetition max, weight lifted will be increased when three sets of ten repetitions can be completed without failure.
Lower body stretching exercise using the easiest rehabilitation elastic Theraband