Investigating the Cognitive Source of Visual Working Memory Impairment in Schizophrenia
Memory Deficits Schizophrenia Neurostimulator; Complications
About this trial
This is an interventional treatment trial for Memory Deficits Schizophrenia Neurostimulator; Complications focused on measuring schizophrenia
Eligibility Criteria
Inclusion Criteria:
- Inform consent acquired
- Age 20 to 65
- Right-handed
- Patients with schizophrenia diagnosed according to DSM-5 criteria
Exclusion Criteria:
- Participants who are pregnant or breastfeeding
- Participants who have metal implants
- Participants who have alcohol/substance use disorder or received electro-convulsive therapy within the past 6 months.
- Participants who have history of head injury with loss of consciousness
- Participants who have history of brain lesions, infection, or epilepsy
- Skin lesions on the electrodes placed
- Cancer patients
- Patients with high fever
- Patients with significant sensory loss
Sites / Locations
- Taipei Medical University Shuang Ho HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Active comparator Within group
Sham comparator Within group
This project will use the StarStim DC stimulator manufactured by Neuroelectrics that was imported with TFDA approval. At the beginning, the participants would be allowed to perform the task which would be followed by application of tACS. The tACS application would be comprised of sham vs active where the sham condition would be given for 30 seconds while the active session would be applied for 15 mins. In tACS, 1mA of theta (6Hz) tACS would be given at the right F4 and P4 electrodes (5*5 cm2, Sponstim® 25). After tACS, the participants would be asked to perform the same task again and the scores (before and after tACS) will be compared and analyzed statistically. Therefore, each patient will need to participate in 2 sessions (active vs. sham), and they will not know which day is which (randomized order).
This project will use the StarStim DC stimulator manufactured by Neuroelectrics that was imported with TFDA approval. At the beginning, the participants would be allowed to perform the task which would be followed by application of tACS. The tACS application would be comprised of sham vs active where the sham condition would be given for 30 seconds while the active session would be applied for 15 mins. In tACS, 1mA of theta (6Hz) tACS would be given at the right F4 and P4 electrodes (5*5 cm2, Sponstim® 25). After tACS, the participants would be asked to perform the same task again and the scores (before and after tACS) will be compared and analyzed statistically. Therefore, each patient will need to participate in 2 sessions (active vs. sham), and they will not know which day is which (randomized order).