Is Myocardial Stunning Induced by Continuous Renal Replacement Therapy a Reality in Critically Ill Patients? (MS-CRRT)
Acute Kidney Injury KDIGO 3, Continuous Renal Replacement Therapy Initiated by the Clinician in Charge Without Emergency, Myocardial Stunning
About this trial
This is an interventional other trial for Acute Kidney Injury KDIGO 3 focused on measuring Acute kidney injury,, continuous renal replacement therapy, myocardial stunning, regional wall motion abnormalities, 2D speckle tracking echocardiography
Eligibility Criteria
Inclusion Criteria:
- Age > 18 years old
- Acute Kidney Injury grade 3 (KDIGO)
- Indication for renal replacement therapy for the clinician in charge
Exclusion Criteria:
- Emergency indication to renal replacement therapy (pH<7.15, Kaliemia > 6mmol/L, refractory pulmonary oedema)
- Poor echogenicity with speckle tracking analysis failure
- Chronic hemodialysis
- Extra corporeal membrane oxygenation, left ventricular assist device.
Sites / Locations
- Département d'anesthésie-réanimation Hôpital cardiologique Louis Pradel Groupe Hospitalier Est
- Ruste MartinRecruiting
- Hopital Edourd HerriotRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Other
Continuous renal replacement therapy arm
Control arm
Echocardiographic evaluation (with 2D speckle tracking analysis of left ventricular segmental function) 1 hour before and 3 hours after the initiation of continuous renal replacement therapy (continuous veno venous hemofiltration) initiation
Two echocardiographic evaluations (with 2D speckle tracking analysis of left ventricular segmental function) at an interval of 4 hours, before the continuous renal replacement therapy initiation.