Back to resultsJUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events
Primary Purpose
Elevated High-sensitivity C-Reactive Protein (hsCRP)
Status
Terminated
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Rosuvastatin
Placebo
Sponsored by
About this trial
This is an interventional prevention trial for Elevated High-sensitivity C-Reactive Protein (hsCRP) focused on measuring Primary prevention, Cardiovascular disease, Statin therapy, C-reactive protein
Eligibility Criteria
Inclusion Criteria: Men 50 years or older, women 60 years or older Low to normal levels of low density lipoprotein (LDL) cholesterol (< 130mg/dL) Elevated levels of C-Reactive Protein (CRP) > 2.0 mg/L Exclusion Criteria: History of cardiovascular or cerebrovascular events Active liver disease Diabetes mellitus Uncontrolled hypertension or hypothyroidism History of certain malignancies Chronic inflammatory conditions History of alcohol or drug abuse
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Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Placebo Comparator
Arm Label
Rosuvastatin
Placebo
Arm Description
Rosuvastatin 20 mg once daily
Placebo once daily
Outcomes
Primary Outcome Measures
Time to Major Cardiac Event (Cardiovascular Death, Stroke, Myocardial Infarction, Hospitalization Due to Unstable Angina or Arterial Revascularization)
Days from randomization to the first of CV death, stroke, MI, hospitalization for unstable angina or arterial revascularization. If no event, censoring occurs at earliest of termination date or efficacy cut-off date of 30 Mar 2008. Events were adjudicated by an endpoint committee. Kaplan-Meier estimate of the mean
Secondary Outcome Measures
Time to Death Due to Any Cause
Days from randomization to death. If no death then censoring occurs at earliest of termination date or efficacy cutoff date of 30 Mar 2008. Kaplan-Meier estimate of the mean
Time to Non-cardiovascular Death
Days from randomization to death from a non-cardiovascular cause. If no event, then censoring occurs at earliest of termination date or efficacy cutoff date of 30 Mar 2008. Events were adjudicated by an endpoint committee. Kaplan-Meier estimate of the mean
Time to Development of Diabetes Mellitus
Days from randomization until development of diabetes. If no diabetes was developed censoring occurred at termination date. Kaplan-Meier estimate of the mean
Time to Venous Thromboembolic Event
Time from randomization to the first venous thromboembolic event. Kaplan-Meier estimate of the mean
Time to Bone Fracture
Days from randomization until bone fracture. If no event, then censoring occurs at earliest of termination date or efficacy cutoff date of 30 Mar 2008. Kaplan-Meier estimate of the mean
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT00239681
Brief Title
JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events
Official Title
A Randomized, Double-Blind, Placebo Controlled, Multicenter, Phase 3 Study of Rosuvastatin (CRESTOR®) 20 mg in the Prevention of Cardiovascular Events Among Subjects With Low Levels of Low Density Lipoprotein(LDL) Cholesterol & Elevated Levels of C-Reactive Protein
Study Type
Interventional
2. Study Status
Record Verification Date
February 2014
Overall Recruitment Status
Terminated
Why Stopped
See detailed description for reason.
Study Start Date
February 2003 (undefined)
Primary Completion Date
September 2008 (Actual)
Study Completion Date
September 2008 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
AstraZeneca
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The purpose of this study is to determine the safety and effectiveness of long-term therapy with rosuvastatin compared with a placebo, and to evaluate whether treatment with rosuvastatin might be effective in reducing the risk of major cardiovascular events.
Detailed Description
AstraZeneca announced it has decided to stop the CRESTOR JUPITER clinical study early based on a recommendation from an Independent Data Monitoring Board and the JUPITER Steering Committee, which met on March 29, 2008. The study will be stopped early because there is unequivocal evidence of a reduction in cardiovascular morbidity and mortality amongst patients who received CRESTOR when compared to placebo.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Elevated High-sensitivity C-Reactive Protein (hsCRP)
Keywords
Primary prevention, Cardiovascular disease, Statin therapy, C-reactive protein
7. Study Design
Primary Purpose
Prevention
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
17802 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Rosuvastatin
Arm Type
Experimental
Arm Description
Rosuvastatin 20 mg once daily
Arm Title
Placebo
Arm Type
Placebo Comparator
Arm Description
Placebo once daily
Intervention Type
Drug
Intervention Name(s)
Rosuvastatin
Other Intervention Name(s)
Crestor
Intervention Description
Oral
Intervention Type
Other
Intervention Name(s)
Placebo
Intervention Description
Oral
Primary Outcome Measure Information:
Title
Time to Major Cardiac Event (Cardiovascular Death, Stroke, Myocardial Infarction, Hospitalization Due to Unstable Angina or Arterial Revascularization)
Description
Days from randomization to the first of CV death, stroke, MI, hospitalization for unstable angina or arterial revascularization. If no event, censoring occurs at earliest of termination date or efficacy cut-off date of 30 Mar 2008. Events were adjudicated by an endpoint committee. Kaplan-Meier estimate of the mean
Time Frame
up to 5 years
Secondary Outcome Measure Information:
Title
Time to Death Due to Any Cause
Description
Days from randomization to death. If no death then censoring occurs at earliest of termination date or efficacy cutoff date of 30 Mar 2008. Kaplan-Meier estimate of the mean
Time Frame
up to 5 years
Title
Time to Non-cardiovascular Death
Description
Days from randomization to death from a non-cardiovascular cause. If no event, then censoring occurs at earliest of termination date or efficacy cutoff date of 30 Mar 2008. Events were adjudicated by an endpoint committee. Kaplan-Meier estimate of the mean
Time Frame
up to 5 years
Title
Time to Development of Diabetes Mellitus
Description
Days from randomization until development of diabetes. If no diabetes was developed censoring occurred at termination date. Kaplan-Meier estimate of the mean
Time Frame
up to 5 years
Title
Time to Venous Thromboembolic Event
Description
Time from randomization to the first venous thromboembolic event. Kaplan-Meier estimate of the mean
Time Frame
up to 5 years
Title
Time to Bone Fracture
Description
Days from randomization until bone fracture. If no event, then censoring occurs at earliest of termination date or efficacy cutoff date of 30 Mar 2008. Kaplan-Meier estimate of the mean
Time Frame
Up to 5 years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
50 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Men 50 years or older, women 60 years or older
Low to normal levels of low density lipoprotein (LDL) cholesterol (< 130mg/dL)
Elevated levels of C-Reactive Protein (CRP) > 2.0 mg/L
Exclusion Criteria:
History of cardiovascular or cerebrovascular events
Active liver disease
Diabetes mellitus
Uncontrolled hypertension or hypothyroidism
History of certain malignancies
Chronic inflammatory conditions
History of alcohol or drug abuse
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Judith Hsia, MD
Organizational Affiliation
AstraZeneca
Official's Role
Study Director
First Name & Middle Initial & Last Name & Degree
Paul Ridker, MD
Organizational Affiliation
Brigham and Women's Hospital
Official's Role
Study Chair
Facility Information:
Facility Name
Research Site
City
Birmingham
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Calera
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Columbiana
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Decatur
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Graysville
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Haleyville
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Hartselle
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Huntsville
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Mobile
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Montgomery
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Muscle Shoals
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
South Birmingham
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Tuscumbia
State/Province
Alabama
Country
United States
Facility Name
Research Site
City
Mesa
State/Province
Arizona
Country
United States
Facility Name
Research Site
City
Phoenix
State/Province
Arizona
Country
United States
Facility Name
Research Site
City
Scottsdale
State/Province
Arizona
Country
United States
Facility Name
Research Site
City
Tucson
State/Province
Arizona
Country
United States
Facility Name
Research Site
City
Fayetteville
State/Province
Arkansas
Country
United States
Facility Name
Research Site
City
Hot Springs
State/Province
Arkansas
Country
United States
Facility Name
Research Site
City
Little Rock
State/Province
Arkansas
Country
United States
Facility Name
Research Site
City
Pine Bluff
State/Province
Arkansas
Country
United States
Facility Name
Research Site
City
Alhambra
State/Province
California
Country
United States
Facility Name
Research Site
City
Azusa
State/Province
California
Country
United States
Facility Name
Research Site
City
Berkeley
State/Province
California
Country
United States
Facility Name
Research Site
City
Beverly Hills
State/Province
California
Country
United States
Facility Name
Research Site
City
Burlingame
State/Province
California
Country
United States
Facility Name
Research Site
City
Carmichael
State/Province
California
Country
United States
Facility Name
Research Site
City
Concord
State/Province
California
Country
United States
Facility Name
Research Site
City
Culver City
State/Province
California
Country
United States
Facility Name
Research Site
City
Daly City
State/Province
California
Country
United States
Facility Name
Research Site
City
Folsom
State/Province
California
Country
United States
Facility Name
Research Site
City
Foothill Ranch
State/Province
California
Country
United States
Facility Name
Research Site
City
Fountain Valley
State/Province
California
Country
United States
Facility Name
Research Site
City
Fresno
State/Province
California
Country
United States
Facility Name
Research Site
City
Garden Grove
State/Province
California
Country
United States
Facility Name
Research Site
City
Inglewood
State/Province
California
Country
United States
Facility Name
Research Site
City
Irvine
State/Province
California
Country
United States
Facility Name
Research Site
City
La Jolla
State/Province
California
Country
United States
Facility Name
Research Site
City
La Mesa
State/Province
California
Country
United States
Facility Name
Research Site
City
Languna Niguel
State/Province
California
Country
United States
Facility Name
Research Site
City
Long Beach
State/Province
California
Country
United States
Facility Name
Research Site
City
Los Angeles
State/Province
California
Country
United States
Facility Name
Research Site
City
Los Gatos
State/Province
California
Country
United States
Facility Name
Research Site
City
Mission Hills
State/Province
California
Country
United States
Facility Name
Research Site
City
Mission Viejo
State/Province
California
Country
United States
Facility Name
Research Site
City
Modesto
State/Province
California
Country
United States
Facility Name
Research Site
City
Newport Beach
State/Province
California
Country
United States
Facility Name
Research Site
City
Norwalk
State/Province
California
Country
United States
Facility Name
Research Site
City
Orangevale
State/Province
California
Country
United States
Facility Name
Research Site
City
Orange
State/Province
California
Country
United States
Facility Name
Research Site
City
Palm Desert
State/Province
California
Country
United States
Facility Name
Research Site
City
Pasadena
State/Province
California
Country
United States
Facility Name
Research Site
City
Pismo Beach
State/Province
California
Country
United States
Facility Name
Research Site
City
Pomona
State/Province
California
Country
United States
Facility Name
Research Site
City
Riverside
State/Province
California
Country
United States
Facility Name
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State/Province
Oklahoma
Country
United States
Facility Name
Research Site
City
Oklahoma City
State/Province
Oklahoma
Country
United States
Facility Name
Research Site
City
Tulsa
State/Province
Oklahoma
Country
United States
Facility Name
Research Site
City
Yukon
State/Province
Oklahoma
Country
United States
Facility Name
Research Site
City
Corvallis
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Dallas
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Eugene
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Lake Oswego
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Medford
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Milwaukie
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Portland
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Springfield
State/Province
Oregon
Country
United States
Facility Name
Research Site
City
Altoona
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Beaver
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Bloomsburg
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Broomall
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Camp Hill
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Connellsville
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Downingtown
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Erie
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Feasterville
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Fleetwood
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Harleysville
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Harrisburg
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Jersey Shore
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
King of Prussia
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Lansdale
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Lansdowne
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Lewisburg
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Lewistown
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Lock Haven
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
McMurry
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Melrose Park
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Norristown
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Philadelphia
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Pittsburgh
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Plymouth Meeting
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Reading
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Scotland
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Sellersville
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Souderton
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Springfield
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
State College
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Stoneboro
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Tipton
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Uniontown
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Upland
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Wallingford
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Warminster
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
West Grove
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
West Reading
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Wilkes-barre
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
York
State/Province
Pennsylvania
Country
United States
Facility Name
Research Site
City
Cranston
State/Province
Rhode Island
Country
United States
Facility Name
Research Site
City
Johnston
State/Province
Rhode Island
Country
United States
Facility Name
Research Site
City
Pawtucket
State/Province
Rhode Island
Country
United States
Facility Name
Research Site
City
Providence
State/Province
Rhode Island
Country
United States
Facility Name
Research Site
City
Charleston
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Greenville
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Greer
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Hampton
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Moncks Corner
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Mt Pleasant
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Orangeburg
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Simpsonville
State/Province
South Carolina
Country
United States
Facility Name
Research Site
City
Sioux Falls
State/Province
South Dakota
Country
United States
Facility Name
Research Site
City
Bristol
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Chattanooga
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Clarksville
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Fayetteville
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Germantown
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Hendersonville
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Jefferson City
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Johnson City
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Memphis
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Morristown
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Nashville
State/Province
Tennessee
Country
United States
Facility Name
Research Site
City
Arlington
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Austin
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Carrollton
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Colleyville
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Corpus Christi
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Dallas
State/Province
Texas
Country
United States
Facility Name
Research Site
City
El Paso
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Fort Worth
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Friendswood
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Ft Worth
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Grapevine
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Houston
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Irving
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Lake Jackson
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Lubbock
State/Province
Texas
Country
United States
Facility Name
Research Site
City
N Richland Hills
State/Province
Texas
Country
United States
Facility Name
Research Site
City
New Braunfels
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Pharr
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Plano
State/Province
Texas
Country
United States
Facility Name
Research Site
City
San Antonio
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Seguin
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Sugar Land
State/Province
Texas
Country
United States
Facility Name
Research Site
City
The Woodlands
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Tyler
State/Province
Texas
Country
United States
Facility Name
Research Site
City
Bountiful
State/Province
Utah
Country
United States
Facility Name
Research Site
City
Nephi
State/Province
Utah
Country
United States
Facility Name
Research Site
City
Salt Lake City
State/Province
Utah
Country
United States
Facility Name
Research Site
City
Burlington
State/Province
Vermont
Country
United States
Facility Name
Research Site
City
Alexandria
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Arlington
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Burke
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Charlottesville
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Hampton
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Hayes
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Norfolk
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Quinton
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Richmond
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Springfield
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Stuart
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Suffolk
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Weber City
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Yorktown
State/Province
Virginia
Country
United States
Facility Name
Research Site
City
Burien
State/Province
Washington
Country
United States
Facility Name
Research Site
City
Everett
State/Province
Washington
Country
United States
Facility Name
Research Site
City
Gig Harbor
State/Province
Washington
Country
United States
Facility Name
Research Site
City
Olympia
State/Province
Washington
Country
United States
Facility Name
Research Site
City
Seattle
State/Province
Washington
Country
United States
Facility Name
Research Site
City
Spokane
State/Province
Washington
Country
United States
Facility Name
Research Site
City
Wenatchee
State/Province
Washington
Country
United States
Facility Name
Research Site
City
Charleston
State/Province
West Virginia
Country
United States
Facility Name
Research Site
City
Lewisburg
State/Province
West Virginia
Country
United States
Facility Name
Research Site
City
Beloit
State/Province
Wisconsin
Country
United States
Facility Name
Research Site
City
Green Bay
State/Province
Wisconsin
Country
United States
Facility Name
Research Site
City
Madison
State/Province
Wisconsin
Country
United States
Facility Name
Research Site
City
Menomonee Falls
State/Province
Wisconsin
Country
United States
Facility Name
Research Site
City
Milwaukee
State/Province
Wisconsin
Country
United States
Facility Name
Research Site
City
Quilmes
State/Province
Buenos Aires - Argentina
Country
Argentina
Facility Name
Research Site
City
Ramos Mejia
State/Province
Buenos Aires Argentina
Country
Argentina
Facility Name
Research Site
City
San Isidro
State/Province
Buenos Aires- Argentina
Country
Argentina
Facility Name
Research Site
City
Capital Federal
State/Province
Buenos Aires
Country
Argentina
Facility Name
Research Site
City
Pilar
State/Province
Buenos Aires
Country
Argentina
Facility Name
Research Site
City
Cordoba
State/Province
Cordoba - Argentina
Country
Argentina
Facility Name
Research Site
City
Rosario
State/Province
Santa Fe- Argentina
Country
Argentina
Facility Name
Research Site
City
San Miguel de Tucuman
State/Province
Tucuman / Argentina
Country
Argentina
Facility Name
Research Site
City
Tucuman
State/Province
Tucuman-argentina
Country
Argentina
Facility Name
Research Site
City
Salta
Country
Argentina
Facility Name
Research Site
City
Alsemberg
Country
Belgium
Facility Name
Research Site
City
ANS
Country
Belgium
Facility Name
Research Site
City
Anthee
Country
Belgium
Facility Name
Research Site
City
Auvelais
Country
Belgium
Facility Name
Research Site
City
Baisy-thy
Country
Belgium
Facility Name
Research Site
City
Bertrix
Country
Belgium
Facility Name
Research Site
City
Betekom
Country
Belgium
Facility Name
Research Site
City
Boechout
Country
Belgium
Facility Name
Research Site
City
Braine-l 'alleud
Country
Belgium
Facility Name
Research Site
City
Brussels
Country
Belgium
Facility Name
Research Site
City
Burdinne
Country
Belgium
Facility Name
Research Site
City
Cerexhe-heuseux
Country
Belgium
Facility Name
Research Site
City
Champion
Country
Belgium
Facility Name
Research Site
City
Chenee
Country
Belgium
Facility Name
Research Site
City
De Pinte
Country
Belgium
Facility Name
Research Site
City
Deurne (antwerpen)
Country
Belgium
Facility Name
Research Site
City
Dour
Country
Belgium
Facility Name
Research Site
City
Ekeren
Country
Belgium
Facility Name
Research Site
City
Embourg
Country
Belgium
Facility Name
Research Site
City
Evergem
Country
Belgium
Facility Name
Research Site
City
Genk
Country
Belgium
Facility Name
Research Site
City
Genly
Country
Belgium
Facility Name
Research Site
City
Gozee
Country
Belgium
Facility Name
Research Site
City
Grivegnee
Country
Belgium
Facility Name
Research Site
City
Halen
Country
Belgium
Facility Name
Research Site
City
Hasselt
Country
Belgium
Facility Name
Research Site
City
Heurne
Country
Belgium
Facility Name
Research Site
City
Heusden
Country
Belgium
Facility Name
Research Site
City
Hove
Country
Belgium
Facility Name
Research Site
City
Kessel-lo
Country
Belgium
Facility Name
Research Site
City
Komen
Country
Belgium
Facility Name
Research Site
City
Kraainem
Country
Belgium
Facility Name
Research Site
City
Landen
Country
Belgium
Facility Name
Research Site
City
Lauwe
Country
Belgium
Facility Name
Research Site
City
Leopoldsburg
Country
Belgium
Facility Name
Research Site
City
Leuven
Country
Belgium
Facility Name
Research Site
City
Libin
Country
Belgium
Facility Name
Research Site
City
Linkebeek
Country
Belgium
Facility Name
Research Site
City
Lommel
Country
Belgium
Facility Name
Research Site
City
Marchienne-au-pont
Country
Belgium
Facility Name
Research Site
City
Marchovelette
Country
Belgium
Facility Name
Research Site
City
Massemen
Country
Belgium
Facility Name
Research Site
City
Mechelen-aan-de-maas
Country
Belgium
Facility Name
Research Site
City
Melsbroek
Country
Belgium
Facility Name
Research Site
City
Moerkerke
Country
Belgium
Facility Name
Research Site
City
Mont-sur-marchienne
Country
Belgium
Facility Name
Research Site
City
Moorsel
Country
Belgium
Facility Name
Research Site
City
Mouscron
Country
Belgium
Facility Name
Research Site
City
Natoye
Country
Belgium
Facility Name
Research Site
City
Oostham
Country
Belgium
Facility Name
Research Site
City
Opgrimbie (maasmechelen)
Country
Belgium
Facility Name
Research Site
City
Oudenaarde
Country
Belgium
Facility Name
Research Site
City
Paal
Country
Belgium
Facility Name
Research Site
City
Puurs
Country
Belgium
Facility Name
Research Site
City
Ronquieres
Country
Belgium
Facility Name
Research Site
City
Ronse
Country
Belgium
Facility Name
Research Site
City
Rumst
Country
Belgium
Facility Name
Research Site
City
Saint-medard
Country
Belgium
Facility Name
Research Site
City
Schoonaarde
Country
Belgium
Facility Name
Research Site
City
Schuiferskapelle
Country
Belgium
Facility Name
Research Site
City
Sint-gillis-waas
Country
Belgium
Facility Name
Research Site
City
Steenokkerzeel
Country
Belgium
Facility Name
Research Site
City
Tavier
Country
Belgium
Facility Name
Research Site
City
Tessenderlo
Country
Belgium
Facility Name
Research Site
City
Thuin
Country
Belgium
Facility Name
Research Site
City
Tielt
Country
Belgium
Facility Name
Research Site
City
Tremelo
Country
Belgium
Facility Name
Research Site
City
Trois-ponts
Country
Belgium
Facility Name
Research Site
City
Turnhout
Country
Belgium
Facility Name
Research Site
City
Vilvoorde
Country
Belgium
Facility Name
Research Site
City
Waremme
Country
Belgium
Facility Name
Research Site
City
Weerde
Country
Belgium
Facility Name
Research Site
City
Wezembeek- Oppem
Country
Belgium
Facility Name
Research Site
City
Zoersel
Country
Belgium
Facility Name
Research Site
City
Maceio
State/Province
Alagoas
Country
Brazil
Facility Name
Research Site
City
Salvador
State/Province
BA
Country
Brazil
Facility Name
Research Site
City
Fortaleza
State/Province
CE
Country
Brazil
Facility Name
Research Site
City
Goiagoianiania
State/Province
Goias
Country
Brazil
Facility Name
Research Site
City
Belo Horizonte
State/Province
MG
Country
Brazil
Facility Name
Research Site
City
Passo Fundo
State/Province
Rio Grande Do Sul
Country
Brazil
Facility Name
Research Site
City
Rio de Janeiro
State/Province
RJ
Country
Brazil
Facility Name
Research Site
City
Porto Alegre
State/Province
RS
Country
Brazil
Facility Name
Research Site
City
Santos
State/Province
Sao Paulo
Country
Brazil
Facility Name
Research Site
City
Sao Jose Do Rio Preto
State/Province
Sao Paulo
Country
Brazil
Facility Name
Research Site
City
Botucatu
State/Province
SP
Country
Brazil
Facility Name
Research Site
City
S.j.rio Preto
State/Province
SP
Country
Brazil
Facility Name
Research Site
City
Campinas
Country
Brazil
Facility Name
Research Site
City
Sao Paulo
Country
Brazil
Facility Name
Research Site
City
Dimitrovgrad
Country
Bulgaria
Facility Name
Research Site
City
Haskovo
Country
Bulgaria
Facility Name
Research Site
City
Pleven
Country
Bulgaria
Facility Name
Research Site
City
Plovdiv
Country
Bulgaria
Facility Name
Research Site
City
Russe
Country
Bulgaria
Facility Name
Research Site
City
Sofia
Country
Bulgaria
Facility Name
Research Site
City
Varna
Country
Bulgaria
Facility Name
Research Site
City
Veliko Tarnovo
Country
Bulgaria
Facility Name
Research Site
City
Calgary
State/Province
Alberta
Country
Canada
Facility Name
Research Site
City
Edmonton
State/Province
Alberta
Country
Canada
Facility Name
Research Site
City
Chilliwack
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
Coquitlam
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
Kelowna
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
Langley
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
New Westminister
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
Penticton
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
Surrey
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
Victoria
State/Province
British Columbia
Country
Canada
Facility Name
Research Site
City
Portage La Prairie
State/Province
Manitoba
Country
Canada
Facility Name
Research Site
City
Winnipeg
State/Province
Manitoba
Country
Canada
Facility Name
Research Site
City
Grand Bay - Westfield
State/Province
New Brunswick
Country
Canada
Facility Name
Research Site
City
Moncton
State/Province
New Brunswick
Country
Canada
Facility Name
Research Site
City
Nackawic
State/Province
New Brunswick
Country
Canada
Facility Name
Research Site
City
Saint John
State/Province
New Brunswick
Country
Canada
Facility Name
Research Site
City
Woodstock
State/Province
New Brunswick
Country
Canada
Facility Name
Research Site
City
Bay Roberts
State/Province
Newfoundland and Labrador
Country
Canada
Facility Name
Research Site
City
Carbonear
State/Province
Newfoundland and Labrador
Country
Canada
Facility Name
Research Site
City
Conception Bay South
State/Province
Newfoundland and Labrador
Country
Canada
Facility Name
Research Site
City
Holyrood
State/Province
Newfoundland and Labrador
Country
Canada
Facility Name
Research Site
City
Mount Pearl
State/Province
Newfoundland and Labrador
Country
Canada
Facility Name
Research Site
City
St. John's
State/Province
Newfoundland and Labrador
Country
Canada
Facility Name
Research Site
City
Amherst
State/Province
Nova Scotia
Country
Canada
Facility Name
Research Site
City
Antigonish
State/Province
Nova Scotia
Country
Canada
Facility Name
Research Site
City
Digby
State/Province
Nova Scotia
Country
Canada
Facility Name
Research Site
City
Halifax
State/Province
Nova Scotia
Country
Canada
Facility Name
Research Site
City
Windsor
State/Province
Nova Scotia
Country
Canada
Facility Name
Research Site
City
Bolton
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Brampton
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Burlington
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Cambridge
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Corunna
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Courtice
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Etobicoke
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Exeter
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Hamilton
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Ingersoll
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Kingston
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
London
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Markham
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Newmarket
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Niagara Falls
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
North Bay
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
North York
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Orleans
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Oshawa
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Ottawa
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Perth
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Peterborough
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Renfrew
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Sarnia
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Scarborough
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Smith Falls
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
St Catherines
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Stirling
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Sudbury
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Thornhill
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Thunder Bay
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Tillsonburg
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Toronto
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Windsor
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Woodstock
State/Province
Ontario
Country
Canada
Facility Name
Research Site
City
Charlottetown
State/Province
Prince Edward Island
Country
Canada
Facility Name
Research Site
City
Chicoutimi
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Courcelette
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Drummonville
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Gatineau
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Granby
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Greenfield Park
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Lasalle
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Laval
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Longueuil
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Montreal
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Pointe-claire
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Saint-georges
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Saint-marc-des-carrieres
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Sainte-catherine
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Sainte-julie
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Sherbrooke
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Trois-rivieres
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Vanier
State/Province
Quebec
Country
Canada
Facility Name
Research Site
City
Regina
State/Province
Saskatchewan
Country
Canada
Facility Name
Research Site
City
Saskatoon
State/Province
Saskatchewan
Country
Canada
Facility Name
Research Site
City
Quebec
Country
Canada
Facility Name
Research Site
City
Temuco
State/Province
Novena Region
Country
Chile
Facility Name
Research Site
City
Santiago
State/Province
Region Metropolitana
Country
Chile
Facility Name
Research Site
City
Medellin
State/Province
Antioquia
Country
Colombia
Facility Name
Research Site
City
Barranquilla
State/Province
Atlantico
Country
Colombia
Facility Name
Research Site
City
Cartagena
State/Province
Bolivar
Country
Colombia
Facility Name
Research Site
City
Pereira
State/Province
Risaralda
Country
Colombia
Facility Name
Research Site
City
Bucaramanga
State/Province
Santander
Country
Colombia
Facility Name
Research Site
City
Floridablanca
State/Province
Santander
Country
Colombia
Facility Name
Research Site
City
Cali
State/Province
Valle
Country
Colombia
Facility Name
Research Site
City
Bogota
Country
Colombia
Facility Name
Research Site
City
Desamparados
State/Province
San Jose
Country
Costa Rica
Facility Name
Research Site
City
Escazu
State/Province
San Jose
Country
Costa Rica
Facility Name
Research Site
City
San Pedro de Montes de Oca
State/Province
San Jose
Country
Costa Rica
Facility Name
Research Site
City
Heredia
Country
Costa Rica
Facility Name
Research Site
City
Gentofte
Country
Denmark
Facility Name
Research Site
City
Glostrup
Country
Denmark
Facility Name
Research Site
City
Herlev
Country
Denmark
Facility Name
Research Site
City
Hillerod
Country
Denmark
Facility Name
Research Site
City
Odense C
Country
Denmark
Facility Name
Research Site
City
El Salvador
State/Province
San Salvador
Country
El Salvador
Facility Name
Research Site
City
Salvador
Country
El Salvador
Facility Name
Research Site
City
San Salvador
Country
El Salvador
Facility Name
Research Site
City
Saku
State/Province
Harju County
Country
Estonia
Facility Name
Research Site
City
Parnu
Country
Estonia
Facility Name
Research Site
City
Rakvere
Country
Estonia
Facility Name
Research Site
City
Tallinn
Country
Estonia
Facility Name
Research Site
City
Tartu
Country
Estonia
Facility Name
Research Site
City
Viljandi County
Country
Estonia
Facility Name
Research Site
City
Berlin
Country
Germany
Facility Name
Research Site
City
Bochum
Country
Germany
Facility Name
Research Site
City
Chemnitz
Country
Germany
Facility Name
Research Site
City
Dortmund
Country
Germany
Facility Name
Research Site
City
Dresden
Country
Germany
Facility Name
Research Site
City
Frankfurt
Country
Germany
Facility Name
Research Site
City
Gorlitz
Country
Germany
Facility Name
Research Site
City
Hamburg
Country
Germany
Facility Name
Research Site
City
Kunzing
Country
Germany
Facility Name
Research Site
City
Leipzig
Country
Germany
Facility Name
Research Site
City
Magdeburg
Country
Germany
Facility Name
Research Site
City
Nurnberg
Country
Germany
Facility Name
Research Site
City
ULM
Country
Germany
Facility Name
Research Site
City
Witten
Country
Germany
Facility Name
Research Site
City
Kiryat Hadassah
State/Province
Jerusalem
Country
Israel
Facility Name
Research Site
City
Ashkelon Shore
Country
Israel
Facility Name
Research Site
City
Beer Yakov
Country
Israel
Facility Name
Research Site
City
Haifa
Country
Israel
Facility Name
Research Site
City
Holon
Country
Israel
Facility Name
Research Site
City
Jerusalem
Country
Israel
Facility Name
Research Site
City
Kfar-saba
Country
Israel
Facility Name
Research Site
City
Safed
Country
Israel
Facility Name
Research Site
City
Tel Aviv
Country
Israel
Facility Name
Research Site
City
Tel-hashomer
Country
Israel
Facility Name
Research Site
City
Zrifin
Country
Israel
Facility Name
Research Site
City
Mexico City
State/Province
D.F
Country
Mexico
Facility Name
Research Site
City
Guadalajara
State/Province
Jalisco
Country
Mexico
Facility Name
Research Site
City
Monterrey
State/Province
Nuevo Leon
Country
Mexico
Facility Name
Research Site
City
Culiacan
State/Province
Sinaloa
Country
Mexico
Facility Name
Research Site
City
San Luis Potosi
State/Province
SLP
Country
Mexico
Facility Name
Research Site
City
Aguascalientes
Country
Mexico
Facility Name
Research Site
City
Alkmaar
Country
Netherlands
Facility Name
Research Site
City
Amersfoort
Country
Netherlands
Facility Name
Research Site
City
Amsterdam
Country
Netherlands
Facility Name
Research Site
City
Breda
Country
Netherlands
Facility Name
Research Site
City
Den Haag
Country
Netherlands
Facility Name
Research Site
City
Deventer
Country
Netherlands
Facility Name
Research Site
City
Eindhoven
Country
Netherlands
Facility Name
Research Site
City
Gouda
Country
Netherlands
Facility Name
Research Site
City
Groningen
Country
Netherlands
Facility Name
Research Site
City
Hoorn
Country
Netherlands
Facility Name
Research Site
City
Leiden
Country
Netherlands
Facility Name
Research Site
City
Nijmegen
Country
Netherlands
Facility Name
Research Site
City
Rotterdam
Country
Netherlands
Facility Name
Research Site
City
Tilburg
Country
Netherlands
Facility Name
Research Site
City
Utrecht
Country
Netherlands
Facility Name
Research Site
City
Velp
Country
Netherlands
Facility Name
Research Site
City
Zoetermeer
Country
Netherlands
Facility Name
Research Site
City
Bekkestua
Country
Norway
Facility Name
Research Site
City
Bergen
Country
Norway
Facility Name
Research Site
City
Boverbru
Country
Norway
Facility Name
Research Site
City
Elverum
Country
Norway
Facility Name
Research Site
City
Flatasen
Country
Norway
Facility Name
Research Site
City
Fredrikstad
Country
Norway
Facility Name
Research Site
City
Halden
Country
Norway
Facility Name
Research Site
City
Heimdal
Country
Norway
Facility Name
Research Site
City
Kristiansand
Country
Norway
Facility Name
Research Site
City
Laksevag
Country
Norway
Facility Name
Research Site
City
Lena
Country
Norway
Facility Name
Research Site
City
Lierskogen
Country
Norway
Facility Name
Research Site
City
Lovenstad
Country
Norway
Facility Name
Research Site
City
Lysaker
Country
Norway
Facility Name
Research Site
City
Moelv
Country
Norway
Facility Name
Research Site
City
Moss
Country
Norway
Facility Name
Research Site
City
Oslo
Country
Norway
Facility Name
Research Site
City
Osteras
Country
Norway
Facility Name
Research Site
City
Paradis
Country
Norway
Facility Name
Research Site
City
Radal
Country
Norway
Facility Name
Research Site
City
Randaberg
Country
Norway
Facility Name
Research Site
City
Skedsmokorset
Country
Norway
Facility Name
Research Site
City
Skiptvet
Country
Norway
Facility Name
Research Site
City
SKI
Country
Norway
Facility Name
Research Site
City
Snaroya
Country
Norway
Facility Name
Research Site
City
Sogndal
Country
Norway
Facility Name
Research Site
City
Spikkestad
Country
Norway
Facility Name
Research Site
City
Stavanger
Country
Norway
Facility Name
Research Site
City
Strommen
Country
Norway
Facility Name
Research Site
City
Svelvik
Country
Norway
Facility Name
Research Site
City
Trollasen
Country
Norway
Facility Name
Research Site
City
Trondheim
Country
Norway
Facility Name
Research Site
City
Panama
Country
Panama
Facility Name
Research Site
City
Aleksandrow Lodzki
Country
Poland
Facility Name
Research Site
City
Bydgoszcz
Country
Poland
Facility Name
Research Site
City
Bytom
Country
Poland
Facility Name
Research Site
City
Chodziez
Country
Poland
Facility Name
Research Site
City
Chorzow
Country
Poland
Facility Name
Research Site
City
Gdansk
Country
Poland
Facility Name
Research Site
City
Gliwice
Country
Poland
Facility Name
Research Site
City
Jelcz-laskowice
Country
Poland
Facility Name
Research Site
City
Karpacz
Country
Poland
Facility Name
Research Site
City
Katowice
Country
Poland
Facility Name
Research Site
City
Koluszki
Country
Poland
Facility Name
Research Site
City
Krakow
Country
Poland
Facility Name
Research Site
City
Linia
Country
Poland
Facility Name
Research Site
City
Lodz
Country
Poland
Facility Name
Research Site
City
Lublin
Country
Poland
Facility Name
Research Site
City
Nowogard
Country
Poland
Facility Name
Research Site
City
Olawa
Country
Poland
Facility Name
Research Site
City
Olsztyn
Country
Poland
Facility Name
Research Site
City
Opalenica
Country
Poland
Facility Name
Research Site
City
Opole
Country
Poland
Facility Name
Research Site
City
Ostrow Wielkopolski
Country
Poland
Facility Name
Research Site
City
Piekary Slaskie
Country
Poland
Facility Name
Research Site
City
Poznan
Country
Poland
Facility Name
Research Site
City
Pulawy
Country
Poland
Facility Name
Research Site
City
Radom
Country
Poland
Facility Name
Research Site
City
Radziejow
Country
Poland
Facility Name
Research Site
City
Rybnik
Country
Poland
Facility Name
Research Site
City
Sieradz
Country
Poland
Facility Name
Research Site
City
Skierniewice
Country
Poland
Facility Name
Research Site
City
Slupca
Country
Poland
Facility Name
Research Site
City
Sobotka
Country
Poland
Facility Name
Research Site
City
Sopot
Country
Poland
Facility Name
Research Site
City
Szczecin
Country
Poland
Facility Name
Research Site
City
Tarnow
Country
Poland
Facility Name
Research Site
City
Torun
Country
Poland
Facility Name
Research Site
City
Trzcianka
Country
Poland
Facility Name
Research Site
City
Turek
Country
Poland
Facility Name
Research Site
City
Wabrzezno
Country
Poland
Facility Name
Research Site
City
Warszawa
Country
Poland
Facility Name
Research Site
City
Wejherowo
Country
Poland
Facility Name
Research Site
City
Wroclaw
Country
Poland
Facility Name
Research Site
City
Zabrze
Country
Poland
Facility Name
Research Site
City
Aguas Buenas
Country
Puerto Rico
Facility Name
Research Site
City
Caguas
Country
Puerto Rico
Facility Name
Research Site
City
Cidra
Country
Puerto Rico
Facility Name
Research Site
City
Levittown-toa Baja
Country
Puerto Rico
Facility Name
Research Site
City
Ponce
Country
Puerto Rico
Facility Name
Research Site
City
San Juan
Country
Puerto Rico
Facility Name
Research Site
City
Cluj Napoca
State/Province
Cluj
Country
Romania
Facility Name
Research Site
City
Timisoara
State/Province
Timis
Country
Romania
Facility Name
Research Site
City
Brasov
Country
Romania
Facility Name
Research Site
City
Bucharest
Country
Romania
Facility Name
Research Site
City
Bucuresti
Country
Romania
Facility Name
Research Site
City
Ekaterinburg
Country
Russian Federation
Facility Name
Research Site
City
Kemerovo
Country
Russian Federation
Facility Name
Research Site
City
Krasnoyarsk
Country
Russian Federation
Facility Name
Research Site
City
Moscow
Country
Russian Federation
Facility Name
Research Site
City
Novosibirsk
Country
Russian Federation
Facility Name
Research Site
City
Saratov
Country
Russian Federation
Facility Name
Research Site
City
St-petersburg
Country
Russian Federation
Facility Name
Research Site
City
Toliatti
Country
Russian Federation
Facility Name
Research Site
City
Tomsk
Country
Russian Federation
Facility Name
Research Site
City
Tyumen
Country
Russian Federation
Facility Name
Research Site
City
Voronezh
Country
Russian Federation
Facility Name
Research Site
City
Yaroslavl
Country
Russian Federation
Facility Name
Research Site
City
Claremont
State/Province
Cape Province
Country
South Africa
Facility Name
Research Site
City
Athlone
State/Province
Cape Town
Country
South Africa
Facility Name
Research Site
City
Florida Park
State/Province
Gauteng
Country
South Africa
Facility Name
Research Site
City
Lenasia
State/Province
Gauteng
Country
South Africa
Facility Name
Research Site
City
Pretoria
State/Province
Gauteng
Country
South Africa
Facility Name
Research Site
City
Witbank
State/Province
Gauteng
Country
South Africa
Facility Name
Research Site
City
Durban
State/Province
Kwazulu Natal
Country
South Africa
Facility Name
Research Site
City
Umkomaas
State/Province
Kwazulu Natal
Country
South Africa
Facility Name
Research Site
City
Morningside Manor
State/Province
Morningside
Country
South Africa
Facility Name
Research Site
City
Korsten
State/Province
Port Elizabeth
Country
South Africa
Facility Name
Research Site
City
Hillcrest
State/Province
Pretoria
Country
South Africa
Facility Name
Research Site
City
Benoni
Country
South Africa
Facility Name
Research Site
City
Halfway House
Country
South Africa
Facility Name
Research Site
City
Johannesburg
Country
South Africa
Facility Name
Research Site
City
Lakeview, Retreat
Country
South Africa
Facility Name
Research Site
City
Rustenburg
Country
South Africa
Facility Name
Research Site
City
Somerset West
Country
South Africa
Facility Name
Research Site
City
Vanderbijlpark
Country
South Africa
Facility Name
Research Site
City
Worcester
Country
South Africa
Facility Name
Research Site
City
Olten
State/Province
Schweiz
Country
Switzerland
Facility Name
Research Site
City
Reading
State/Province
Berkshire
Country
United Kingdom
Facility Name
Research Site
City
Annan
State/Province
Dumfries and Galloway
Country
United Kingdom
Facility Name
Research Site
City
Blantyre
State/Province
Lanarkshire
Country
United Kingdom
Facility Name
Research Site
City
Hamilton
State/Province
Lanarkshire
Country
United Kingdom
Facility Name
Research Site
City
Strathaven
State/Province
Lanarkshire
Country
United Kingdom
Facility Name
Research Site
City
Wishaw
State/Province
Lanarkshire
Country
United Kingdom
Facility Name
Research Site
City
Paisley
State/Province
Renfrewshire
Country
United Kingdom
Facility Name
Research Site
City
Airdrie
State/Province
Scotland
Country
United Kingdom
Facility Name
Research Site
City
Glasgow
State/Province
Scotland
Country
United Kingdom
Facility Name
Research Site
City
Barrhead
Country
United Kingdom
Facility Name
Research Site
City
Bellshill
Country
United Kingdom
Facility Name
Research Site
City
Birmingham
Country
United Kingdom
Facility Name
Research Site
City
Cambuslang
Country
United Kingdom
Facility Name
Research Site
City
Cardiff
Country
United Kingdom
Facility Name
Research Site
City
Chorley
Country
United Kingdom
Facility Name
Research Site
City
Cumbernauld
Country
United Kingdom
Facility Name
Research Site
City
Gourock
Country
United Kingdom
Facility Name
Research Site
City
Greenock
Country
United Kingdom
Facility Name
Research Site
City
Helensburgh
Country
United Kingdom
Facility Name
Research Site
City
Kirkintilloch
Country
United Kingdom
Facility Name
Research Site
City
Liverpool
Country
United Kingdom
Facility Name
Research Site
City
Lockerbie
Country
United Kingdom
Facility Name
Research Site
City
Manchester
Country
United Kingdom
Facility Name
Research Site
City
New Stevenson
Country
United Kingdom
Facility Name
Research Site
City
Renfrew
Country
United Kingdom
Facility Name
Research Site
City
Stranraer
Country
United Kingdom
Facility Name
Research Site
City
Strathblane
Country
United Kingdom
Facility Name
Research Site
City
Thornhill
Country
United Kingdom
Facility Name
Research Site
City
Wolverhampton
Country
United Kingdom
Facility Name
Research Site
City
Montevideo
Country
Uruguay
Facility Name
Research Site
City
Maracay, Municipio Girardot
State/Province
Estado Aragua
Country
Venezuela
Facility Name
Research Site
City
Barinas
State/Province
Estado Barinas
Country
Venezuela
Facility Name
Research Site
City
Ciudad Bolivar
State/Province
Estado Bolivar
Country
Venezuela
Facility Name
Research Site
City
Puerto Ordaz
State/Province
Estado Bolivar
Country
Venezuela
Facility Name
Research Site
City
Valencia
State/Province
Estado Carabobo
Country
Venezuela
Facility Name
Research Site
City
Barquisimeto
State/Province
Estado Lara
Country
Venezuela
Facility Name
Research Site
City
Merida
State/Province
Estado Merida
Country
Venezuela
Facility Name
Research Site
City
Porlamar
State/Province
Estado Nueva Esparta
Country
Venezuela
Facility Name
Research Site
City
Maracaibo
State/Province
Estado Zulia
Country
Venezuela
Facility Name
Research Site
City
Latrinidad Caracas
State/Province
Municipio Baruta
Country
Venezuela
Facility Name
Research Site
City
Caracas
Country
Venezuela
Facility Name
Research Site
City
Punto Fijo, Estado Falcon
Country
Venezuela
12. IPD Sharing Statement
Citations:
PubMed Identifier
32799709
Citation
Ajala ON, Demler OV, Liu Y, Farukhi Z, Adelman SJ, Collins HL, Ridker PM, Rader DJ, Glynn RJ, Mora S. Anti-Inflammatory HDL Function, Incident Cardiovascular Events, and Mortality: A Secondary Analysis of the JUPITER Randomized Clinical Trial. J Am Heart Assoc. 2020 Sep;9(17):e016507. doi: 10.1161/JAHA.119.016507. Epub 2020 Aug 15.
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Akinkuolie AO, Lawler PR, Chu AY, Caulfield M, Mu J, Ding B, Nyberg F, Glynn RJ, Ridker PM, Hurt-Camejo E, Chasman DI, Mora S. Group IIA Secretory Phospholipase A2, Vascular Inflammation, and Incident Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1182-1190. doi: 10.1161/ATVBAHA.118.311894.
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PubMed Identifier
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PubMed Identifier
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Khera AV, Demler OV, Adelman SJ, Collins HL, Glynn RJ, Ridker PM, Rader DJ, Mora S. Cholesterol Efflux Capacity, High-Density Lipoprotein Particle Number, and Incident Cardiovascular Events: An Analysis From the JUPITER Trial (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin). Circulation. 2017 Jun 20;135(25):2494-2504. doi: 10.1161/CIRCULATIONAHA.116.025678. Epub 2017 Apr 27.
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Akinkuolie AO, Glynn RJ, Padmanabhan L, Ridker PM, Mora S. Circulating N-Linked Glycoprotein Side-Chain Biomarker, Rosuvastatin Therapy, and Incident Cardiovascular Disease: An Analysis From the JUPITER Trial. J Am Heart Assoc. 2016 Jul 13;5(7):e003822. doi: 10.1161/JAHA.116.003822.
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PubMed Identifier
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Dugani SB, Akinkuolie AO, Paynter N, Glynn RJ, Ridker PM, Mora S. Association of Lipoproteins, Insulin Resistance, and Rosuvastatin With Incident Type 2 Diabetes Mellitus : Secondary Analysis of a Randomized Clinical Trial. JAMA Cardiol. 2016 May 1;1(2):136-45. doi: 10.1001/jamacardio.2016.0096.
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PubMed Identifier
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Lawler PR, Akinkuolie AO, Chandler PD, Moorthy MV, Vandenburgh MJ, Schaumberg DA, Lee IM, Glynn RJ, Ridker PM, Buring JE, Mora S. Circulating N-Linked Glycoprotein Acetyls and Longitudinal Mortality Risk. Circ Res. 2016 Apr 1;118(7):1106-15. doi: 10.1161/CIRCRESAHA.115.308078. Epub 2016 Mar 7.
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Mora S, Caulfield MP, Wohlgemuth J, Chen Z, Superko HR, Rowland CM, Glynn RJ, Ridker PM, Krauss RM. Atherogenic Lipoprotein Subfractions Determined by Ion Mobility and First Cardiovascular Events After Random Allocation to High-Intensity Statin or Placebo: The Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) Trial. Circulation. 2015 Dec 8;132(23):2220-9. doi: 10.1161/CIRCULATIONAHA.115.016857. Epub 2015 Sep 25.
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PubMed Identifier
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Chu AY, Giulianini F, Barratt BJ, Ding B, Nyberg F, Mora S, Ridker PM, Chasman DI. Differential Genetic Effects on Statin-Induced Changes Across Low-Density Lipoprotein-Related Measures. Circ Cardiovasc Genet. 2015 Oct;8(5):688-95. doi: 10.1161/CIRCGENETICS.114.000962. Epub 2015 Aug 13.
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PubMed Identifier
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Everett BM, Zeller T, Glynn RJ, Ridker PM, Blankenberg S. High-sensitivity cardiac troponin I and B-type natriuretic Peptide as predictors of vascular events in primary prevention: impact of statin therapy. Circulation. 2015 May 26;131(21):1851-60. doi: 10.1161/CIRCULATIONAHA.114.014522. Epub 2015 Mar 30.
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PubMed Identifier
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Everett BM, Mora S, Glynn RJ, MacFadyen J, Ridker PM. Safety profile of subjects treated to very low low-density lipoprotein cholesterol levels (<30 mg/dl) with rosuvastatin 20 mg daily (from JUPITER). Am J Cardiol. 2014 Dec 1;114(11):1682-9. doi: 10.1016/j.amjcard.2014.08.041. Epub 2014 Sep 16.
Results Reference
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PubMed Identifier
25437881
Citation
Pena JM, Aspberg S, MacFadyen J, Glynn RJ, Solomon DH, Ridker PM. Statin therapy and risk of fracture: results from the JUPITER randomized clinical trial. JAMA Intern Med. 2015 Feb;175(2):171-7. doi: 10.1001/jamainternmed.2014.6388.
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PubMed Identifier
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Khera AV, Everett BM, Caulfield MP, Hantash FM, Wohlgemuth J, Ridker PM, Mora S. Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin). Circulation. 2014 Feb 11;129(6):635-42. doi: 10.1161/CIRCULATIONAHA.113.004406. Epub 2013 Nov 17.
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PubMed Identifier
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Mora S, Glynn RJ, Ridker PM. High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy. Circulation. 2013 Sep 10;128(11):1189-97. doi: 10.1161/CIRCULATIONAHA.113.002671. Epub 2013 Sep 3.
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PubMed Identifier
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Ridker PM, Pradhan A, MacFadyen JG, Libby P, Glynn RJ. Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial. Lancet. 2012 Aug 11;380(9841):565-71. doi: 10.1016/S0140-6736(12)61190-8.
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PubMed Identifier
22516441
Citation
Mora S, Glynn RJ, Boekholdt SM, Nordestgaard BG, Kastelein JJ, Ridker PM. On-treatment non-high-density lipoprotein cholesterol, apolipoprotein B, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy: JUPITER (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin). J Am Coll Cardiol. 2012 Apr 24;59(17):1521-8. doi: 10.1016/j.jacc.2011.12.035.
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PubMed Identifier
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PubMed Identifier
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Dorresteijn JA, Visseren FL, Ridker PM, Wassink AM, Paynter NP, Steyerberg EW, van der Graaf Y, Cook NR. Estimating treatment effects for individual patients based on the results of randomised clinical trials. BMJ. 2011 Oct 3;343:d5888. doi: 10.1136/bmj.d5888.
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PubMed Identifier
21742096
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Albert MA, Glynn RJ, Fonseca FA, Lorenzatti AJ, Ferdinand KC, MacFadyen JG, Ridker PM. Race, ethnicity, and the efficacy of rosuvastatin in primary prevention: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial. Am Heart J. 2011 Jul;162(1):106-14.e2. doi: 10.1016/j.ahj.2011.03.032. Epub 2011 Jun 12.
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PubMed Identifier
21493817
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Ridker PM, MacFadyen JG, Glynn RJ, Chasman DI. Kinesin-like protein 6 (KIF6) polymorphism and the efficacy of rosuvastatin in primary prevention. Circ Cardiovasc Genet. 2011 Jun;4(3):312-7. doi: 10.1161/CIRCGENETICS.110.959353. Epub 2011 Apr 14.
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PubMed Identifier
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Koenig W, Ridker PM. Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk >/= 5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authorities. Eur Heart J. 2011 Jan;32(1):75-83. doi: 10.1093/eurheartj/ehq370. Epub 2010 Oct 22.
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PubMed Identifier
20736443
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Ridker PM, Macfadyen JG, Nordestgaard BG, Koenig W, Kastelein JJ, Genest J, Glynn RJ. Rosuvastatin for primary prevention among individuals with elevated high-sensitivity c-reactive protein and 5% to 10% and 10% to 20% 10-year risk. Implications of the Justification for Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial for "intermediate risk". Circ Cardiovasc Qual Outcomes. 2010 Sep;3(5):447-52. doi: 10.1161/CIRCOUTCOMES.110.938118. Epub 2010 Aug 24.
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PubMed Identifier
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Ridker PM, Genest J, Boekholdt SM, Libby P, Gotto AM, Nordestgaard BG, Mora S, MacFadyen JG, Glynn RJ, Kastelein JJ; JUPITER Trial Study Group. HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial. Lancet. 2010 Jul 31;376(9738):333-9. doi: 10.1016/S0140-6736(10)60713-1. Epub 2010 Jul 23.
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PubMed Identifier
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Ridker PM, MacFadyen J, Cressman M, Glynn RJ. Efficacy of rosuvastatin among men and women with moderate chronic kidney disease and elevated high-sensitivity C-reactive protein: a secondary analysis from the JUPITER (Justification for the Use of Statins in Prevention-an Intervention Trial Evaluating Rosuvastatin) trial. J Am Coll Cardiol. 2010 Mar 23;55(12):1266-1273. doi: 10.1016/j.jacc.2010.01.020. Epub 2010 Mar 4.
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Ridker PM, MacFadyen JG, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group. Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin (JUPITER). Circ Cardiovasc Qual Outcomes. 2009 Nov;2(6):616-23. doi: 10.1161/CIRCOUTCOMES.109.848473. Epub 2009 Sep 22.
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Everett BM, Glynn RJ, MacFadyen JG, Ridker PM. Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER). Circulation. 2010 Jan 5;121(1):143-50. doi: 10.1161/CIRCULATIONAHA.109.874834. Epub 2009 Dec 21.
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Glynn RJ, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Ridker PM. A randomized trial of rosuvastatin in the prevention of venous thromboembolism. N Engl J Med. 2009 Apr 30;360(18):1851-61. doi: 10.1056/NEJMoa0900241. Epub 2009 Mar 29.
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Results Reference
derived
Links:
URL
http://filehosting.pharmacm.com/DownloadService.ashx?client=CTR_MED_6111&studyid=317&filename=CSR-D3560L00030.pdf
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JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events
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