Ketamine for Pain Relief in Bariatric Surgery
Postoperative Pain
About this trial
This is an interventional treatment trial for Postoperative Pain focused on measuring ketamine, fentanyl, postoperative pain
Eligibility Criteria
Inclusion Criteria:
- Patients of age 18-60 years
- BMI > 35 kg/m2
- Either sex
- ASA physical status II & III
- undergoing laparoscopic bariatric surgery
Exclusion Criteria:
- Patients refusal
- ASA physical status: IV
- History of hypersensitivity to fentanyl and/or ketamine
- Chronic opioid use
- History of substance abuse
- Metabolic disorders
- Seizure disorder
Sites / Locations
- Sir Ganga Ram Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Ketamine + Fentanyl Group
Fentanyl Group
Patients will receive pre-induction fentanyl 1-mcg/kg, ketamine 0.5-mg/kg after induction, followed by intraoperative fentanyl infusion of 0.5-mcg/kg/hr + ketamine infusion of 0.2-mg/kg/hr. Postoperative analgesia will be provided with Intravenous Patient Controlled Analgesia (IV-PCA) pump containing fentanyl citrate-2.5 mcg/ml, which will be attached to all the patients upon shifting to the recovery room. The IV-PCA pump settings will be as follows: 0-ml basal dose; 4-ml PCA dose; 15-minutes lock out interval.
Patients will receive pre-induction fentanyl 1-mcg/kg,followed by intraoperative fentanyl infusion of 0.5-mcg/kg/hr. Postoperative analgesia will be provided with Intravenous Patient Controlled Analgesia (IV-PCA) pump containing fentanyl citrate-2.5 mcg/ml, which will be attached to all the patients upon shifting to the recovery room. The IV-PCA pump settings will be as follows: 0-ml basal dose; 4-ml PCA dose; 15-minutes lock out interval.