Language Stimuli Screening in Children
Primary Purpose
Language Disorder, Healthy
Status
Completed
Phase
Locations
United States
Study Type
Observational
Intervention
Sponsored by
About this trial
This is an observational trial for Language Disorder focused on measuring Reading, Naming
Eligibility Criteria
INCLUSION CRITERIA: Children will be between the ages 4 and 8 are eligible. EXCLUSION CRITERIA: Children who meet one of the following criteria are not eligible: IQ below 70; History of neurologic or psychiatric disorders; History of an language disorder; Performing below grade-level; Non-native English speaker.
Sites / Locations
- National Institute of Neurological Disorders and Stroke (NINDS)
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
NCT ID
NCT00016796
First Posted
June 2, 2001
Last Updated
March 3, 2008
Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
1. Study Identification
Unique Protocol Identification Number
NCT00016796
Brief Title
Language Stimuli Screening in Children
Official Title
Language Stimuli Screening in Children
Study Type
Observational
2. Study Status
Record Verification Date
March 2005
Overall Recruitment Status
Completed
Study Start Date
May 2001 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
March 2005 (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
4. Oversight
5. Study Description
Brief Summary
This study will determine baseline language skills in children 4 to 8 years old. The data will be used to design studies using functional magnetic resonance imaging (fMRI) to identify what areas of the brain in children are involved in understanding language. This information is important for children who require brain surgery to control seizures.
Healthy normal volunteers between the ages of 4 and 8 years who have an IQ of 70 or more; who have no history of neurologic, psychiatric or language disorder; who are performing at or above grade level, and who are native English speakers may be eligible for this study.
Participants will be asked to do the following:
name pictures or read words that appear on a computer screen
listen to stories and answer questions about them
match pictures to a spoken word
The children's responses will be recorded.
Detailed Description
We propose to study normal children to establish baseline data to use to develop novel sets of stimuli for functional imaging paradigms. Tasks using these stimuli will include object naming, sentence comprehension, and single word reading.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Language Disorder, Healthy
Keywords
Reading, Naming
7. Study Design
Enrollment
150 (false)
10. Eligibility
Sex
All
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
INCLUSION CRITERIA:
Children will be between the ages 4 and 8 are eligible.
EXCLUSION CRITERIA:
Children who meet one of the following criteria are not eligible:
IQ below 70;
History of neurologic or psychiatric disorders;
History of an language disorder;
Performing below grade-level;
Non-native English speaker.
Facility Information:
Facility Name
National Institute of Neurological Disorders and Stroke (NINDS)
City
Bethesda
State/Province
Maryland
ZIP/Postal Code
20892
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
9109891
Citation
Hertz-Pannier L, Gaillard WD, Mott SH, Cuenod CA, Bookheimer SY, Weinstein S, Conry J, Papero PH, Schiff SJ, Le Bihan D, Theodore WH. Noninvasive assessment of language dominance in children and adolescents with functional MRI: a preliminary study. Neurology. 1997 Apr;48(4):1003-12. doi: 10.1212/wnl.48.4.1003.
Results Reference
background
PubMed Identifier
8239568
Citation
Devinsky O, Perrine K, Llinas R, Luciano DJ, Dogali M. Anterior temporal language areas in patients with early onset of temporal lobe epilepsy. Ann Neurol. 1993 Nov;34(5):727-32. doi: 10.1002/ana.410340517.
Results Reference
background
PubMed Identifier
9169209
Citation
Cycowicz YM, Friedman D, Rothstein M, Snodgrass JG. Picture naming by young children: norms for name agreement, familiarity, and visual complexity. J Exp Child Psychol. 1997 May;65(2):171-237. doi: 10.1006/jecp.1996.2356.
Results Reference
background
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Language Stimuli Screening in Children
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