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LIVES: Personalized Lifestyle Intervention for Patients With Depression (LIVES)

Primary Purpose

Cardiovascular Risk, Depression, Unipolar, Depression, Bipolar

Status
Recruiting
Phase
Not Applicable
Locations
Netherlands
Study Type
Interventional
Intervention
LIVE
Sponsored by
University Medical Center Groningen
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Cardiovascular Risk focused on measuring depression, lifestyle, mental health care, general practice

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: For patients in mental health care only: Outpatients Diagnosed during intake, the primary diagnosis being chronic bipolar disorder (type I or 2) or a chronic or recurrent severe depression in the narrower sense of the word Receiving psychopharmacological treatment Have had a physical and lifestyle Routine Outcome Monitoring measurement showing that three or more metabolic parameters were outside the normal range For patients in general practice only: Diagnosis of depressive symptoms or depressive disorder in the past year as registered in the general practice electronic health record and coded according to the International Classification of Primary Care (ICPC) as P03 and P76, respectively, At least mild depressive symptom level according to the Beck Depression Inventory-II (BDI) (score ≥14) Body mass index ≥ 25 kg/m2 or increased waist circumference (>88cm (women) of >102cm (men)). For both patient groups: - 18 years or older and capable to participate in the intervention according to the treating physician Availability of one or two people close to the patient (friends or family, preferably sharing the same household), i.e. to act as the buddy of the patient. Exclusion Criteria: For GP patients only: current treatment in mental health care (GGZ in Dutch) For GP patients only: severe somatic / neurological disease at the discretion of the GP Currently participating in another lifestyle intervention Insufficient proficiency in Dutch Unability to read and write

Sites / Locations

  • GGZ DrentheRecruiting
  • University Medical Center GroningenRecruiting

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Intervention

Arm Description

Lifestyle intervention

Outcomes

Primary Outcome Measures

Reach of LIVE
Reach of our intervention as defined by the absolute number, proportion, and representativeness of individuals who are willing to participate in LIVE
Adherence to LIVE
Adherence to the LIVE lifestyle intervention as defined by the number of sessions attended by the participant out of the total of 18 sessions
Drop out from LIVE
Drop-out from the LIVE intervention as defined by the proportion of participants who decide to prematurely stop taking part in the LIVE intervention
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed

Secondary Outcome Measures

Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Quality of life as assessed by The Manchester Short Assessment of Quality of Life (MANSA).
The MANSA measures quality of life focusing on satisfaction with life as a whole and with life domains and consists of a 12-item self-report questionnaire
Depressive symptoms according to the Beck Depression Inventory-II (BDI-II)
The BDI-II is a self-report (21 items) rating inventory which measures depressive symptom level
Recovery of the participant according to the Individual Recovery Outcomes Counter (I.ROC)
The I.ROC is an instrument to quantitatively measure recovery. It uses three indicators on four areas of wellbeing, namely home, opportunity, people, empowerment.
Wellbeing as assessed by the Mental Health Continuum Short Form (MHC-SF)
The MHC-SF measures emotional, social and psychological wellbeing and is a self-report with 14 items
Sleep quality as assessed by the Pittsburgh Sleep Quality Index (PSQI)
The PSQI is a self-report questionnaire that assesses sleep quality over a one-month interval and consists of 19 individual items.
Alcohol consumption and alcohol-related problems according to the Alcohol Use Disorders Identification test (AUDIT)
The AUDIT consists of 10 items scoring both consumption and alcohol-related problems. We will use the total scale on consumption and problem drinking
Treatment success according to the Outcome Questionnaire-45
a questionnaire to measure treatment success. It has three subscales: 1. Symptomatic distress (25 items, including symptoms of depression, anxiety and drug dependency, 2. Interpersonal relations (11 items) en 3. Social Role (9 items) .
Dietary intake of the participant according to a self deviced questionnaire
The questionnaire is a nutrition list with 25 items to measure the dietary intake of patients
Activity level defined as the daily number of steps
The daily number of steps will be measured using the Fitbit Zip as described by Naslund et al., 2016
Body height of the participant as assessed by a stadiometer
Body height in meters
Body weight of the participant as assessed by a medical weight scale
Body weight in kilograms
Waist circumference of the participant as assessed using a tape meter line
Waist circumference in centimeters

Full Information

First Posted
December 16, 2022
Last Updated
March 1, 2023
Sponsor
University Medical Center Groningen
Collaborators
GGZ Drenthe Mental Health Institution
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1. Study Identification

Unique Protocol Identification Number
NCT05767073
Brief Title
LIVES: Personalized Lifestyle Intervention for Patients With Depression
Acronym
LIVES
Official Title
LIVES: Development of/a Personalized Lifestyle Intervention for Patients With Depression in Psychiatric Outpatient Care and General Practice in a Pilot Study
Study Type
Interventional

2. Study Status

Record Verification Date
March 2023
Overall Recruitment Status
Recruiting
Study Start Date
September 1, 2020 (Actual)
Primary Completion Date
June 1, 2023 (Anticipated)
Study Completion Date
June 1, 2023 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University Medical Center Groningen
Collaborators
GGZ Drenthe Mental Health Institution

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
Persons with affective disorder have a considerably increased risk of cardiovascular disease. To a considerable extent, this is due to an unhealthy life style. At present, no adequate lifestyle interventions are available for these patients. In the present pilot intervention study we study the acceptability and feasibility of a newly developed lifestyle intervention that is specifically tailored to the needs of patients with affective disorders treated in mental health care or general practice.
Detailed Description
Rationale: Patients with bipolar disorder and severe depressions have a 10-year shorter life expectancy, on average, than the population as a whole. Also patients with less severe depression are still at a substantially increased risk of cardiovascular events. This may be attributed primarily to somatic complications resulting from a largely sedentary existence and an unhealthy lifestyle related to their disorder and/or the side effects of psychopharmacological treatment. Generally speaking, multimodal lifestyle interventions are about as effective as medication in reducing cardiovascular risks. Very little research has been conducted into the effect of lifestyle interventions among outpatients in mental health care or patients with mental health problems in general practice. This study seeks to examine the extent to which a personalised lifestyle approach can promote the physical health and quality of life of outpatients and general practice patients with affective disorders. Objective: The objective of this study is to develop a personalised state-of-the art lifestyle intervention that is both feasible and acceptable to outpatients with bipolar and severe recurrent depressive disorder and to patients with depression in general practice Study design: An explorative pilot study (n = 38) with baseline measurement and different follow-up measurements during and after the intervention. Study population: Patients (18-65 years old) with bipolar disorder or severe recurrent depression who are being treated at GGZ Drenthe (N=30) and patients with depression in primary care (N=8). Intervention (if applicable): A personalised multimodal lifestyle intervention consisting of several modules comprising both individual and group sessions. The support network is involved during the individual sessions. Main study parameters/endpoints: Feasibility and acceptability of the lifestyle intervention.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Cardiovascular Risk, Depression, Unipolar, Depression, Bipolar
Keywords
depression, lifestyle, mental health care, general practice

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Model Description
Un controlled cohort study
Masking
None (Open Label)
Allocation
N/A
Enrollment
38 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Intervention
Arm Type
Experimental
Arm Description
Lifestyle intervention
Intervention Type
Behavioral
Intervention Name(s)
LIVE
Intervention Description
The lifestyle intervention Coaching on Lifestyle (CooL) (van Rinsum 2018)),formed the basis of LIVE and was adapted to specific dysfunctional elements in depressed patients regarding motivation and self-management. The focus is on reducing depressive symptoms, enhancing the quality of life and possibly achieving weight loss. The lifestyle intervention lasts six months, with 13 weekly 1.5 to 2 hour group sessions and five 45 to 60 -minute individual sessions with at least one person from the patient's support network of friends or family (preferably sharing the same household). All sessions end with individual homework exercises, and each session starts with a 10 to 15-minute positive psychology intervention (PPI) and 5 to 15 minutes of physical activity. These sessions are followed by two booster sessions after about two and six months. Groups consist of 4-8 people.
Primary Outcome Measure Information:
Title
Reach of LIVE
Description
Reach of our intervention as defined by the absolute number, proportion, and representativeness of individuals who are willing to participate in LIVE
Time Frame
27 months (September 2020 through November 2022)
Title
Adherence to LIVE
Description
Adherence to the LIVE lifestyle intervention as defined by the number of sessions attended by the participant out of the total of 18 sessions
Time Frame
18 weeks
Title
Drop out from LIVE
Description
Drop-out from the LIVE intervention as defined by the proportion of participants who decide to prematurely stop taking part in the LIVE intervention
Time Frame
18 weeks
Title
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 3
Title
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 6
Title
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 9
Title
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 12
Title
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 15
Title
Feasibility and acceptability of the LIVE intervention according to the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability of the LIVE intervention will be assessed using qualitative interviews Participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 18
Secondary Outcome Measure Information:
Title
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 3
Title
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 6
Title
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 9
Title
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 12
Title
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 15
Title
Feasibility and acceptability of the LIVE intervention according to the buddy of the participant as assessed by qualitative interviews and qualitative data analysis
Description
Feasibility and acceptability will be assessed using qualitative interviews. Buddies of participants will be interrogated on how they experienced themes during the different modules of the intervention. A topic-list will be used by the interviewer to check whether all relevant themes on feasibility and acceptability have been discussed
Time Frame
Up to week 18
Title
Quality of life as assessed by The Manchester Short Assessment of Quality of Life (MANSA).
Description
The MANSA measures quality of life focusing on satisfaction with life as a whole and with life domains and consists of a 12-item self-report questionnaire
Time Frame
Baseline, at the end of the intervention 18 weeks after baseline, and at the 6 months follow up (42 weeks after baseline)
Title
Depressive symptoms according to the Beck Depression Inventory-II (BDI-II)
Description
The BDI-II is a self-report (21 items) rating inventory which measures depressive symptom level
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)
Title
Recovery of the participant according to the Individual Recovery Outcomes Counter (I.ROC)
Description
The I.ROC is an instrument to quantitatively measure recovery. It uses three indicators on four areas of wellbeing, namely home, opportunity, people, empowerment.
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)
Title
Wellbeing as assessed by the Mental Health Continuum Short Form (MHC-SF)
Description
The MHC-SF measures emotional, social and psychological wellbeing and is a self-report with 14 items
Time Frame
Baseline, halfway and at the end of the intervention 18 weeks after the intervention, and at the 6 months follow up (42 weeks after baseline)
Title
Sleep quality as assessed by the Pittsburgh Sleep Quality Index (PSQI)
Description
The PSQI is a self-report questionnaire that assesses sleep quality over a one-month interval and consists of 19 individual items.
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)
Title
Alcohol consumption and alcohol-related problems according to the Alcohol Use Disorders Identification test (AUDIT)
Description
The AUDIT consists of 10 items scoring both consumption and alcohol-related problems. We will use the total scale on consumption and problem drinking
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)
Title
Treatment success according to the Outcome Questionnaire-45
Description
a questionnaire to measure treatment success. It has three subscales: 1. Symptomatic distress (25 items, including symptoms of depression, anxiety and drug dependency, 2. Interpersonal relations (11 items) en 3. Social Role (9 items) .
Time Frame
The questionnaire will be administered after every five modules of the intervention.
Title
Dietary intake of the participant according to a self deviced questionnaire
Description
The questionnaire is a nutrition list with 25 items to measure the dietary intake of patients
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)
Title
Activity level defined as the daily number of steps
Description
The daily number of steps will be measured using the Fitbit Zip as described by Naslund et al., 2016
Time Frame
From baseline up to the 6 months follow up (42 weeks after baseline)
Title
Body height of the participant as assessed by a stadiometer
Description
Body height in meters
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)
Title
Body weight of the participant as assessed by a medical weight scale
Description
Body weight in kilograms
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)
Title
Waist circumference of the participant as assessed using a tape meter line
Description
Waist circumference in centimeters
Time Frame
Baseline, at the end of the intervention (18 weeks), and at the 6 months follow up (42 weeks after baseline)

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: For patients in mental health care only: Outpatients Diagnosed during intake, the primary diagnosis being chronic bipolar disorder (type I or 2) or a chronic or recurrent severe depression in the narrower sense of the word Receiving psychopharmacological treatment Have had a physical and lifestyle Routine Outcome Monitoring measurement showing that three or more metabolic parameters were outside the normal range For patients in general practice only: Diagnosis of depressive symptoms or depressive disorder in the past year as registered in the general practice electronic health record and coded according to the International Classification of Primary Care (ICPC) as P03 and P76, respectively, At least mild depressive symptom level according to the Beck Depression Inventory-II (BDI) (score ≥14) Body mass index ≥ 25 kg/m2 or increased waist circumference (>88cm (women) of >102cm (men)). For both patient groups: - 18 years or older and capable to participate in the intervention according to the treating physician Availability of one or two people close to the patient (friends or family, preferably sharing the same household), i.e. to act as the buddy of the patient. Exclusion Criteria: For GP patients only: current treatment in mental health care (GGZ in Dutch) For GP patients only: severe somatic / neurological disease at the discretion of the GP Currently participating in another lifestyle intervention Insufficient proficiency in Dutch Unability to read and write
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Huibert Burger, MD PhD
Phone
+31(0)50 361 6722
Ext
6722
Email
h.burger@umcg.nl
First Name & Middle Initial & Last Name or Official Title & Degree
Edith Liemburg, PhD
Phone
+31 6 10589718
Ext
9718
Email
e.j.liemburg@umcg.nl
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Danielle Cath, MD PhD
Organizational Affiliation
University Medical Center Groningen
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Marjolein Berger, MD PhD
Organizational Affiliation
University Medical Center Groningen
Official's Role
Principal Investigator
Facility Information:
Facility Name
GGZ Drenthe
City
Assen
State/Province
Drenthe
ZIP/Postal Code
9404 LA
Country
Netherlands
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Danielle Cath, MD PhD
Phone
+31 6 82843069
Ext
3069
Email
danielle.cath@ggzdrenthe.nl
First Name & Middle Initial & Last Name & Degree
Edith Liemburg, PhD
Phone
+31 6 10589718
Email
e.j.liemburg@umcg.nl
First Name & Middle Initial & Last Name & Degree
Danielle Cath, MD PhD
Facility Name
University Medical Center Groningen
City
Groningen
ZIP/Postal Code
9700 AD
Country
Netherlands
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Huibert Burger, MD PhD
Phone
+31(0)50 361 6724
Ext
6724
Email
h.burger@umcg.nl
First Name & Middle Initial & Last Name & Degree
Patrick Brink
Phone
+31 6 52724353
Email
p.brink@umcg.nl
First Name & Middle Initial & Last Name & Degree
Marjolein Berger, MD PHD

12. IPD Sharing Statement

Plan to Share IPD
No
Citations:
PubMed Identifier
17591509
Citation
Ormel J, Von Korff M, Burger H, Scott K, Demyttenaere K, Huang YQ, Posada-Villa J, Pierre Lepine J, Angermeyer MC, Levinson D, de Girolamo G, Kawakami N, Karam E, Medina-Mora ME, Gureje O, Williams D, Haro JM, Bromet EJ, Alonso J, Kessler R. Mental disorders among persons with heart disease - results from World Mental Health surveys. Gen Hosp Psychiatry. 2007 Jul-Aug;29(4):325-34. doi: 10.1016/j.genhosppsych.2007.03.009.
Results Reference
background
PubMed Identifier
17470664
Citation
Knol MJ, Heerdink ER, Egberts AC, Geerlings MI, Gorter KJ, Numans ME, Grobbee DE, Klungel OH, Burger H. Depressive symptoms in subjects with diagnosed and undiagnosed type 2 diabetes. Psychosom Med. 2007 May;69(4):300-5. doi: 10.1097/PSY.0b013e31805f48b9. Epub 2007 Apr 30.
Results Reference
background

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LIVES: Personalized Lifestyle Intervention for Patients With Depression

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