Long Term Immunogenicity Study of Engerix-B Vaccine in 10 Year Old Children and the Effect of Booster Injections
Hepatitis B, Vaccination
About this trial
This is an interventional prevention trial for Hepatitis B focused on measuring Hepatitis B, Vaccination, Engerix-B, Immunogenicity, Long-term immunity, Booster dose, Safety
Eligibility Criteria
Inclusion Criteria: Previously completed the 1995 to 1996 Hepatitis B vaccination program vaccinations (Primary study) to the best of his/her knowledge and already enrolled and followed in the long term study Must be HBc negative Required standard interval between last dose of primary immunization and booster vaccination Written informed consent obtained from the subject Free of obvious health problems as established by medical history and clinical examination before entering into the study Previously completed routine childhood vaccination to the best of his/her knowledge If the subject is female, and the potential of pregnancy exists, it must be asked prior to immunization by the study nurse. According to the protocol d'immunisation du Québec, Engerix-B is not contra-indicated during pregnancy. However, if a participant thinks she could be pregnant (sexually active and no oral contraception or intra uterine device), a pregnancy test will be carried out. In case of pregnancy, the booster vaccination will be performed after delivery. Exclusion Criteria: - Not applicable
Sites / Locations
- Vladimir Gilca