Magnetic Resonance Imaging of Medial Meniscal Posterior Root Tear
Primary Purpose
Medial Meniscus, Posterior Horn Derangement
Status
Completed
Phase
Not Applicable
Locations
Egypt
Study Type
Interventional
Intervention
Magnetic Resonance Imaging of the knee
Knee Arthroscopy
Sponsored by
About this trial
This is an interventional diagnostic trial for Medial Meniscus, Posterior Horn Derangement
Eligibility Criteria
Inclusion Criteria:
- Patients of either sex from more than 16 years, having acute or chronic painful knee associated with popping sounds are included in this study.
Exclusion Criteria:
- Patients who are contraindicated to Magnetic Resonance Imaging examination as those who have artificial cardiac pacemaker or metallic prosthesis not compatible with Magnetic Resonance Imaging or those with severe claustrophobia.
Sites / Locations
- Ashgan Ali Abdo Qardash
Arms of the Study
Arm 1
Arm Type
Other
Arm Label
Magnetic resonance imaging of the knee
Arm Description
Patients complain of painful knee with clinical suspicious of medial meniscus posterior root tear of the knee will be examined by all Magnetic Resonance Imaging sequences including sagittal, coronal and axial PD,T2 and PD-SPIR weighted images, and correlate the results with Knee Arthroscopy.while the suspected cases of meniscal extrusion will make MRI using the knee coil for varus stress Overloading simulating weight bearing.
Outcomes
Primary Outcome Measures
Patients complain of painful knee joint associated with popping sounds and clinically suspected of medial meniscal posterior root tear will examined by Magnetic Resonance Imaging
Correlation the results of Magnetic Resonance Imaging with gold standard knee Arthroscopy.
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT03632707
Brief Title
Magnetic Resonance Imaging of Medial Meniscal Posterior Root Tear
Official Title
Role of Magnetic Resonance Imaging in the Diagnosis of Posterior Medial Meniscal Root Tear of the Knee
Study Type
Interventional
2. Study Status
Record Verification Date
January 2022
Overall Recruitment Status
Completed
Study Start Date
February 1, 2019 (Actual)
Primary Completion Date
January 1, 2022 (Actual)
Study Completion Date
February 1, 2022 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Assiut University
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
The aim of this study is to evaluate and analyze the role of magnetic resonance imaging in the diagnosis of medial meniscal posterior root tears, including the normal variations in meniscal anatomy that may resemble a meniscal tear, and identifying the causes or nature of posterior medial meniscal root tear(degenerative versus traumatic) and correlate the results with the standard reference knee Arthroscopy.In addition to identifying and estimating the suspected cases of meniscal extrusion by making MRI with stress varus overloading simulating weight bearing.
Detailed Description
The knee joint is one of the most important joints in the human body responsible for weight-bearing and a group of complex movements during ordinary life activities and even in vigorous sports making it susceptible to different traumatic injuries.Knee pain is considered as one of the most common complaints of patients presenting to clinical practitioners.There are many structures within the knee which can cause pain. By far, one of the most common causes of knee pain is a meniscus tear.The meniscus is the most important cushion in the knee; It plays an important bio mechanical role in axial load distribution of the knees. If the meniscus is injured and the cushioning is lost, arthritis and pain can occur.Menisci can tear due to traumatic injury or degenerative wear, meniscal root tears are a type of meniscal tear in the knee where the tear extends to either the anterior or posterior meniscal root attachment to the central tibial plateau. They often tend to be radial tears extending into the root.The medial meniscal posterior root tear can occur especially in middle-aged or older patients who have a single event of posteromedial painful popping sensation during light activities.Magnetic resonance imaging is well established as the best imaging modality for evaluating a patient with suspected meniscal pathology, involving the medial meniscal posterior horn root.In recent years, posterior meniscal root tears have received increasing attention in both Arthroscopic and Magnetic resonance study. All sequences of Magnetic resonance imaging should be reviewed, but T2 weighted coronal sections should provide the best visualization of the posterior roots. The Magnetic resonance findings of a medial meniscal posterior radial root tear are shortening or absence of the root (ghost sign) on sagittal images and a vertical fluid cleft with truncation sign and features of meniscal extrusion on coronal images.
It is very important to avoid errors in diagnosing meniscal root tears. So interpreting Magnetic resonance examinations of the knee need to be aware of the attachments of the menisci and to understand the normal variations in meniscal anatomy that may resemble a meniscal tear.
Tears of the meniscal root are relatively uncommon, occurring in 2.2% - 9.8% of patients undergoing Magnetic resonance imaging of the knee.However, it is important that these tears be diagnosed as several complications of meniscal root tear, including meniscal extrusion, secondary osteoarthritis, and subchondral insufficiency fracture.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Medial Meniscus, Posterior Horn Derangement
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
30 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Magnetic resonance imaging of the knee
Arm Type
Other
Arm Description
Patients complain of painful knee with clinical suspicious of medial meniscus posterior root tear of the knee will be examined by all Magnetic Resonance Imaging sequences including sagittal, coronal and axial PD,T2 and PD-SPIR weighted images, and correlate the results with Knee Arthroscopy.while the suspected cases of meniscal extrusion will make MRI using the knee coil for varus stress Overloading simulating weight bearing.
Intervention Type
Radiation
Intervention Name(s)
Magnetic Resonance Imaging of the knee
Intervention Description
After clinical assessment, all the patients will examined by Magnetic Resonance Imaging to diagnose the medial meniscal posterior root tear,and the suspected cases of meniscal extrusion will make MRI using the knee coil for varus stress Overloading simulating weight bearing
Intervention Type
Procedure
Intervention Name(s)
Knee Arthroscopy
Intervention Description
Correlate all the magnetic resonance imaging results with the Knee Arthroscopy
Primary Outcome Measure Information:
Title
Patients complain of painful knee joint associated with popping sounds and clinically suspected of medial meniscal posterior root tear will examined by Magnetic Resonance Imaging
Description
Correlation the results of Magnetic Resonance Imaging with gold standard knee Arthroscopy.
Time Frame
6 months
10. Eligibility
Sex
All
Minimum Age & Unit of Time
16 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Patients of either sex from more than 16 years, having acute or chronic painful knee associated with popping sounds are included in this study.
Exclusion Criteria:
Patients who are contraindicated to Magnetic Resonance Imaging examination as those who have artificial cardiac pacemaker or metallic prosthesis not compatible with Magnetic Resonance Imaging or those with severe claustrophobia.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Nisreen A. Abbas, MD
Organizational Affiliation
Assiut University
Official's Role
Study Director
Facility Information:
Facility Name
Ashgan Ali Abdo Qardash
City
Assiut
Country
Egypt
12. IPD Sharing Statement
Plan to Share IPD
No
Citations:
PubMed Identifier
23199751
Citation
Barile A, Conti L, Lanni G, Calvisi V, Masciocchi C. Evaluation of medial meniscus tears and meniscal stability: weight-bearing MRI vs arthroscopy. Eur J Radiol. 2013 Apr;82(4):633-9. doi: 10.1016/j.ejrad.2012.10.018. Epub 2012 Nov 28.
Results Reference
background
PubMed Identifier
23091292
Citation
Park HJ, Kim SS, Lee SY, Choi YJ, Chung EC, Rho MH, Kwag HJ. Medial meniscal root tears and meniscal extrusion transverse length ratios on MRI. Br J Radiol. 2012 Nov;85(1019):e1032-7. doi: 10.1259/bjr/26261821.
Results Reference
result
PubMed Identifier
28852346
Citation
Carreau JH, Sitton SE, Bollier M. Medial Meniscus Root Tear in the Middle Aged Patient: A Case Based Review. Iowa Orthop J. 2017;37:123-132.
Results Reference
result
PubMed Identifier
15208101
Citation
Costa CR, Morrison WB, Carrino JA. Medial meniscus extrusion on knee MRI: is extent associated with severity of degeneration or type of tear? AJR Am J Roentgenol. 2004 Jul;183(1):17-23. doi: 10.2214/ajr.183.1.1830017.
Results Reference
result
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Magnetic Resonance Imaging of Medial Meniscal Posterior Root Tear
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