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Marijuana Treatment Project - 3 (MTP-3)

Primary Purpose

Marijuana Dependence

Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Reinforcement for homework completion
Reinforcement for Abstinence
Case Management
Sponsored by
UConn Health
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Marijuana Dependence focused on measuring marijuana dependence, self-efficacy, coping skills, attendance, marijuana abstinence

Eligibility Criteria

18 Years - 80 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Cannabis dependence Willing to accept random assignment to interventions Exclusion Criteria: Current dependence on alcohol or other drugs Problems that require inpatient hospitalization Reading ability below fifth grade level Lack of reliable transportation to treatment Excessive commuting distance

Sites / Locations

  • University of Connecticut Health Center

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm Type

Experimental

Active Comparator

Active Comparator

Arm Label

Reinforcement for homework completion

Reinforcement for Abstinence

Case Management

Arm Description

Outcomes

Primary Outcome Measures

Marijuana abstinence
Self-efficacy, use of coping skills, and treatment attendance

Secondary Outcome Measures

Continuous abstinence will be predicted by (a) treatment attendance; (b) posttreatment self-efficacy for coping; and (c) use of coping skills

Full Information

First Posted
April 5, 2005
Last Updated
July 27, 2017
Sponsor
UConn Health
Collaborators
National Institute on Drug Abuse (NIDA)
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1. Study Identification

Unique Protocol Identification Number
NCT00107588
Brief Title
Marijuana Treatment Project - 3
Acronym
MTP-3
Official Title
Contingency Management for Marijuana Dependence
Study Type
Interventional

2. Study Status

Record Verification Date
July 2017
Overall Recruitment Status
Completed
Study Start Date
February 2007 (undefined)
Primary Completion Date
April 2011 (Actual)
Study Completion Date
August 2012 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
UConn Health
Collaborators
National Institute on Drug Abuse (NIDA)

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The goal of this research is to improve treatment outcome for marijuana-dependent individuals. The current study builds on the findings of our prior NIDA-funded marijuana treatment study in which improved client outcomes were associated with greater treatment attendance, greater client self-efficacy, and greater use of coping skills. We will use a contingency management paradigm to provide tangible reinforcement for completing homework assignments that are designed to enhance coping skills. It is anticipated that this will result in greater homework compliance, leading to greater self-efficacy regarding one's ability to cope with high-risk situations. Improved self-efficacy will enhance the likelihood of employing coping skills in high-risk situations, thereby increasing the probability of achieving and maintaining abstinence.
Detailed Description
Participants will receive an intervention combining one session of motivational enhancement therapy with eight sessions of cognitive-behavioral coping skills therapy (MET+CBT). A contingency management procedure will be added to this intervention, providing reinforcement for completion of homework, as verified by call-ins to an Interactive Voice Recording (IVR) system. Outcomes will be compared to an MET+CBT intervention in which reinforcement will be provided for marijuana-free urine specimens, and to a control group that receives Case Management. Recruitment of 234 marijuana-dependent participants will occur over a three-year period. They will be randomly assigned to one of the three 9-session interventions. Treatment will be individual, manualized, and provided on an outpatient basis. Pretreatment assessments will obtain baseline data; follow-up assessments at three-month intervals for one year will evaluate marijuana use outcomes, other drug or alcohol use, and psychosocial functioning. It is anticipated that the intervention in which completion of homework is reinforced will result in the best outcomes. The mechanisms by which the interventions result in behavior change will be the specific focus of attention in this study.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Marijuana Dependence
Keywords
marijuana dependence, self-efficacy, coping skills, attendance, marijuana abstinence

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
215 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Reinforcement for homework completion
Arm Type
Experimental
Arm Title
Reinforcement for Abstinence
Arm Type
Active Comparator
Arm Title
Case Management
Arm Type
Active Comparator
Intervention Type
Behavioral
Intervention Name(s)
Reinforcement for homework completion
Intervention Description
Provides contingent reinforcement for engaging in homework activities designed to enhance coping skills
Intervention Type
Behavioral
Intervention Name(s)
Reinforcement for Abstinence
Intervention Description
Provides contingent reinforcement for submitting marijuana-free urine specimen
Intervention Type
Behavioral
Intervention Name(s)
Case Management
Intervention Description
Will control for the effect of therapist-client contact by providing supportive case management as an active control condition.
Primary Outcome Measure Information:
Title
Marijuana abstinence
Time Frame
One-year follow-up period
Title
Self-efficacy, use of coping skills, and treatment attendance
Time Frame
During 2-month treatment period
Secondary Outcome Measure Information:
Title
Continuous abstinence will be predicted by (a) treatment attendance; (b) posttreatment self-efficacy for coping; and (c) use of coping skills
Time Frame
One-year follow-up period

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
80 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Cannabis dependence Willing to accept random assignment to interventions Exclusion Criteria: Current dependence on alcohol or other drugs Problems that require inpatient hospitalization Reading ability below fifth grade level Lack of reliable transportation to treatment Excessive commuting distance
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Mark D Litt, Ph.D.
Organizational Affiliation
UConn Health
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Connecticut Health Center
City
Farmington
State/Province
Connecticut
ZIP/Postal Code
06030-3910
Country
United States

12. IPD Sharing Statement

Learn more about this trial

Marijuana Treatment Project - 3

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