Maturation of Follicles After Transplantation of Ovarian Tissue Into the Pelvic Wall and the Ovary (Ovartrans)
Infertility, Ovarian Failure, Premature
About this trial
This is an interventional treatment trial for Infertility focused on measuring Infertility, Ovarian Failure, Premature, Ovarian Follicle, Ovary, Tissue Transplantation, Cryopreservation, Pelvis, Chemotherapy, Pregnancy Rate, Folliculogenesis, Endometrium, Estrogens, Progestins, Follicle Stimulating Hormone, Estradiol, Progesterone, Hormones, Maturation of Follicles, Pregnant Women, Premature Menopause, Ovarian Insufficiency, Ovarian Insufficiency, Premature, Cytotoxic therapy, Fertility Protection, Reproductive Medicine, Reproductive Techniques, Reproductive Technology, Cryotherapy, Pregnancy
Eligibility Criteria
Inclusion Criteria:
- Age at cryopreservation ot tissue max. 38 years
- Age at transplantation 18-49 years
- At least one maintained ovary
- Premature ovarian failure
- Indication for an autologous transplantation of ovarian tissue
- Permitted pregnancy from the part of the oncologists
- Written informed consent
Exclusion Criteria:
- Age at transplantation <18 and >49 years
- Cryopreservation in the context of a leucaemia, neuroblastoma, Burkitt-lymphoma
Important: Inclusion is only done by one of the recruiting centers. Study participation will only be given on invitation. Please contact Principal Investigator!
Sites / Locations
- Universitätsfrauenklinik, Abteilung für Gynäkologische Endokrinologie und Reproduktionsmedizin
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Transplantation into pelvic wall
Transplantation into the ovary
Ovarian transplantation into the pelvic wall after cryopreservation of ovarian tissue before cytotoxic therapies
Ovarian transplantation into ovary after cryopreservation of ovarian tissue before cytotoxic therapies