Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD)
About this trial
This is an interventional treatment trial for Chronic Obstructive Pulmonary Disease (COPD)
Eligibility Criteria
Inclusion Criteria: male/female aged between 40-70 inclusive COPD defined by GOLD criteria FEV1 greater or equal to 60% of predicted without medication baseline FEV1 greater or equal than 1.2L 10 or more pack years no hard contraindications for use of beta blockers being able to perform technically acceptable pulmonary function tests signed informed consent systolic blood pressure equal to 130 or greater Exclusion Criteria: instable COPD during the month before visit 1 usage of corticosteroids during the month before visit 1 significant pulmonary diseases other than COPD a history of cancer within the last 5 years (basal cell carcinoma or cutaneous squamous cell carcinoma allowed) a recent history of myocardial infarction use of an investigational drug within one month or six half lives (which ever is greater) of visit 1 contra-indications for the use of ipratropium-bromide
Sites / Locations
- Martini HospitalRecruiting