Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Neuropathic Pain, Phantom Limb Pain
About this trial
This is an interventional treatment trial for Neuropathic Pain focused on measuring Guided Plasticity therapy, Phantom Motor Execution, Mindful SensoriMotor Therapy, Brain Modulation, transcranial Direct Current Stimulation (tDCS), Neurological disorders, Neurobehavioral Manifestations
Eligibility Criteria
Inclusion criteria
- The participant has given written informed consent to participate.
- The participant must have chronic neuropathic pain due to sensorimotor impairment (example PLP).
- At least six months should be passed since the date of injury (acute pain cases should not be included in the study).
- If the participant is under pharmacological treatments, there must be no variations on the medication dosages (steady consumption) for at least 1 month before the screening visit.
- If the participant has previously been treated for neuropathic pain, the last session of that treatment(s) must be at least 3 months before the screening visit.
- Any pain reduction potentially correlated to previous neuropathic pain treatments must have been observed at least 3 months prior to the screening visit, as reported by the participant.
- In the case of having a prosthesis, the participant must be in a stable prosthetic situation (i.e. satisfied with the fitting of the prosthesis or not using a prosthesis).
- Participants must have enough contact surface at the site of the amputation or the injured nerves for the system to work, in the researcher's opinion.
- Participants must be able to perceive the haptic stimulation at the time of the screening visit.
- Participants must not experience painful sensations from haptic stimulation in the stump (i.e. allodynia).
- The participant has a sufficient understanding of both Swedish and English to be able to participate in all study assessments, in the researcher's opinion.
- Participants should not have any other condition or symptoms that can prevent them from participating in the study, in the researcher's opinion.
- No mental inability, reluctance, or language difficulties that result in difficulty understanding the meaning of study participation, in the researcher's opinion.
- The participant should not have any condition associated with the risk of poor protocol compliance, in the researcher's opinion.
Exclusion criteria
- The potential participant will be excluded from the study if the person does not meet at least one of the inclusion criteria.
Sites / Locations
- Center for Bionics and Pain Research, CBPR
Arms of the Study
Arm 1
Experimental
Mindful SensoriMotor Therapy Enhanced with Brain Modulation
The participant can choose between one, two, or five interventions per week depending on their availability. Steps of each intervention: Pain Evaluation: Numeric Rating Scale (NRS) Functional Assessments (1st, 5th, 10th, and last sessions) Preparation: Locate participant in a comfortable position for training (comfortable chair, about a meter distance to the screen, pleasant arm position) Placement of the surface electrodes Positioning of the feedback wearable device over the affected body part Placement of the brain modulation cap Treatment modalities: Motor training Sensory training Sensorimotor training Assessments Step 4 is repeated for different phantom movements, initially one at a time, progressing to several joints simultaneously. A treatment session lasts 2 hours.