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Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis

Primary Purpose

Knee Osteoarthritis

Status
Completed
Phase
Not Applicable
Locations
Pakistan
Study Type
Interventional
Intervention
Macquarie Injury Management group
Mulligan Mobilization with Movement
Sponsored by
Riphah International University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Knee Osteoarthritis focused on measuring Knee Pain, Movement with Mobilization

Eligibility Criteria

50 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • ACR criteria for knee will be over age 50
  • less than 30 minutes of morning stiffness,
  • Crepitus on active motion,
  • Tenderness
  • Enlargement
  • No palpable warmth of synovium.
  • Osteoarthritis grade 1 and 2 by Kelly-green and Lawrence method.

Exclusion Criteria:

  • Any surgical procedure done in past 6 months and metal implants in lower extremity.
  • Any infection and neoplastic disorder.
  • Post traumatic knee stiffness.
  • Secondary knee O A peripheral vascular disease

Sites / Locations

  • Riphah Rehabilitation Center

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Macquarie Injury Management group

Mulligan Mobilization with Movement

Arm Description

Outcomes

Primary Outcome Measures

Visual Analogue scale
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."
WOMAC
The scores for each subscale are summed up, with a possible score range of 0-20 for Pain, 0-8 for Stiffness, and 0-68 for Physical Function. Usually a sum of the scores for all three subscales gives a total WOMAC score, however there are other methods that have been used to combine scores.

Secondary Outcome Measures

Full Information

First Posted
March 25, 2021
Last Updated
August 27, 2021
Sponsor
Riphah International University
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1. Study Identification

Unique Protocol Identification Number
NCT04818307
Brief Title
Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis
Official Title
Long Term Effects of Mulligan Mobilization With Movement Versus Macquarie Injury Management Group on Function and Pain of Knee Osteoarthritis
Study Type
Interventional

2. Study Status

Record Verification Date
August 2021
Overall Recruitment Status
Completed
Study Start Date
April 1, 2020 (Actual)
Primary Completion Date
November 30, 2020 (Actual)
Study Completion Date
December 30, 2020 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Riphah International University

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
Knee pain is one of the most usual pain that commonly affects people especially in the late age. It can be caused by osteoarthritis, poor posture or sitting position, bad bending or improper lifting. It is usually not caused by a serious illness. It is the most common cause of disability. To compare the long term effects of Mulligan Mobilization with Movement versus Macquarie Injury Management Group on pain and function of knee osteoarthritis.
Detailed Description
It was a randomized clinical trial conducted in Revival Physiotherapy Center, Lahore. A convenient sample of 26 diagnosed patients with osteoarthritis was included in the study. Subjects were randomly distributed in to two groups with use of flip coin method Group of randomization. Group 1 patients got MIMG with routine physical therapy and Group 2 got MWM with routine physical therapy. Visual analogue Scale (VAS),Non modified WOMAC were used to assess all patients before and after 4 weeks of intervention. Statistical analysis was computed by SPSS 20.0.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Knee Osteoarthritis
Keywords
Knee Pain, Movement with Mobilization

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantOutcomes Assessor
Allocation
Randomized
Enrollment
26 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Macquarie Injury Management group
Arm Type
Experimental
Arm Title
Mulligan Mobilization with Movement
Arm Type
Active Comparator
Intervention Type
Other
Intervention Name(s)
Macquarie Injury Management group
Intervention Description
Group A was treated by MIMG (soft tissue mobilization) with base line treatment (Hot pack for 10 mint, Quadriceps Isometrics, Stretching). For the application of technique subject lies supine with extended knee, therapist places both hands on the knee and gently apply soft tissue release. This procedure was applied for 2 to 3 minutes.
Intervention Type
Other
Intervention Name(s)
Mulligan Mobilization with Movement
Intervention Description
Group B was treated by Mulligan Mobilization with movement with base line treatment (Hot Pack for 10 mints, Quadriceps Isometrics, Stretching). For the application of technique subject lies supine with 30 degree knee flexion, therapist places right hand below the knee and left hand above the knee. Apply the lateral glide on the joint. This procedure was applied for 3 times.
Primary Outcome Measure Information:
Title
Visual Analogue scale
Description
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."
Time Frame
6 months
Title
WOMAC
Description
The scores for each subscale are summed up, with a possible score range of 0-20 for Pain, 0-8 for Stiffness, and 0-68 for Physical Function. Usually a sum of the scores for all three subscales gives a total WOMAC score, however there are other methods that have been used to combine scores.
Time Frame
6 months

10. Eligibility

Sex
All
Minimum Age & Unit of Time
50 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: ACR criteria for knee will be over age 50 less than 30 minutes of morning stiffness, Crepitus on active motion, Tenderness Enlargement No palpable warmth of synovium. Osteoarthritis grade 1 and 2 by Kelly-green and Lawrence method. Exclusion Criteria: Any surgical procedure done in past 6 months and metal implants in lower extremity. Any infection and neoplastic disorder. Post traumatic knee stiffness. Secondary knee O A peripheral vascular disease
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Maryam Shabbir
Organizational Affiliation
Riphah International University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Riphah Rehabilitation Center
City
Lahore
State/Province
Punjab
ZIP/Postal Code
54000
Country
Pakistan

12. IPD Sharing Statement

Plan to Share IPD
No
Citations:
Citation
Kandada S, Heggannavar A. Effect of Mulligan's MWM versus Macquarie Injury Management Group (MIMG) protocol on pain and function in osteoarthritis of knee: a randomised clinical trial. IJTRR. 2015;4(4):125-31.
Results Reference
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PubMed Identifier
23559821
Citation
Bhatia D, Bejarano T, Novo M. Current interventions in the management of knee osteoarthritis. J Pharm Bioallied Sci. 2013 Jan;5(1):30-8. doi: 10.4103/0975-7406.106561.
Results Reference
background
PubMed Identifier
2287948
Citation
Felson DT. The epidemiology of knee osteoarthritis: results from the Framingham Osteoarthritis Study. Semin Arthritis Rheum. 1990 Dec;20(3 Suppl 1):42-50. doi: 10.1016/0049-0172(90)90046-i.
Results Reference
background
PubMed Identifier
15381791
Citation
Felson DT, Gale DR, Elon Gale M, Niu J, Hunter DJ, Goggins J, Lavalley MP. Osteophytes and progression of knee osteoarthritis. Rheumatology (Oxford). 2005 Jan;44(1):100-4. doi: 10.1093/rheumatology/keh411. Epub 2004 Sep 20.
Results Reference
background
PubMed Identifier
8129467
Citation
Cooper C, McAlindon T, Coggon D, Egger P, Dieppe P. Occupational activity and osteoarthritis of the knee. Ann Rheum Dis. 1994 Feb;53(2):90-3. doi: 10.1136/ard.53.2.90.
Results Reference
background
PubMed Identifier
24899883
Citation
Alshami AM. Knee osteoarthritis related pain: a narrative review of diagnosis and treatment. Int J Health Sci (Qassim). 2014 Jan;8(1):85-104. doi: 10.12816/0006075.
Results Reference
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Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis

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