Multicentre Radial Artery Patency Study: Results of Patency Beyond 5 Years After Coronary Artery Bypass Surgery (RAPS - 5 years)
Coronary Artery Disease
About this trial
This is an interventional treatment trial for Coronary Artery Disease focused on measuring Coronary Bypass Surgery, Coronary Artery Disease, Angiography, Arterial Grafts, Radial Artery, Saphenous Vein
Eligibility Criteria
Inclusion Criteria: The patient population consists of patients who were enroled into the original Multicentre Radial Artery Patency Study between November 1996 and January 2001. These included patients undergoing isolated coronary artery bypass surgery less than 80 years of age with 3 vessel coronary disease and left ventricular ejection fraction greater than 35%. Exclusion Criteria: Exclusion criteria included 1: Inability to use the radial artery or saphenous vein conduits: a)nonpalpable ulnar arteries or a positive Allen's test, b) an abnormal Doppler study or ultrasonographic study of the arms, c) a history of vasculitis or Raynaud's syndrome, bilateral varicose veins or vein stripping. 2: Conditions that affected the safety of follow-up angiography: a)renal insufficiency (creatinine > 180 umol/L) b)severe peripheral vascular disease precluding femoral access b)coagulopathy or obligatory uninterrupted use of anticoagulants c) known allergy to radiographic contrast media d) women of childbearing potential e) comorbid illness which precludes the use of follow up angiography f) geographically inaccessible for follow up angiography.
Sites / Locations
- University of Alberta
- Manitoba Health Sciences Centre
- London Health Sciences Centre - UC
- London Health Sciences Centre - VC
- Ottawa Heart Institute
- Sunnybrook and Women's College HSC
- St. Michael's Hospital
- Toronto General Hospital
- Vancouver General Hospital
- Laval Hospital
- Montreal Heart Institute
- Montreal Jewish General Hospital
- Waikato Hospital
Arms of the Study
Arm 1
Experimental
Surgical Conduit
The surgical arm will be composed of the experimental arm (the use of the radial artery) versus an active comparator (the use of the saphenous vein graft).