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Multisensorial Information's Treatment in Autism Spectrum Disorder

Primary Purpose

Autism

Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
memory test
Sponsored by
Centre Hospitalier Universitaire de Nice
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Autism

Eligibility Criteria

7 Years - 13 Years (Child)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Boy or girl,
  • 7 - 13 years,
  • Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS,
  • Upper total IQ or equal to 50, examination dating less than year before the inclusion,
  • French-speaking children,
  • Signature of the informed consent by the parents(relatives) and the child,
  • Membership to the Social Security.

Exclusion Criteria:

  • Genetic, neurological or neurosensory pathologies,
  • Diagnosis of intrusive disorder(confusion) of the not specified development: TED our,
  • The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm Type

    Other

    Other

    Arm Label

    autistic patient

    healthy volunteers

    Arm Description

    patient with autistic trouble

    healthy volunteers

    Outcomes

    Primary Outcome Measures

    rate of reminder after 30 minutes between the group autistic and the group witness( %)
    Comparison between the group autistic and the group witness of the difference enter the rate of reminder(abseiling) in 30 minutes of the words proposed in video and audio sequences.

    Secondary Outcome Measures

    Difference of the scores of reminders words (%)
    Difference of the scores of reminders between the both group, immediately after procedure and 30 minutes after procedure

    Full Information

    First Posted
    September 29, 2015
    Last Updated
    October 16, 2015
    Sponsor
    Centre Hospitalier Universitaire de Nice
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    1. Study Identification

    Unique Protocol Identification Number
    NCT02579109
    Brief Title
    Multisensorial Information's Treatment in Autism Spectrum Disorder
    Official Title
    Exploring Social Cognition in Autism Spectrum Disorder With Long Time Memory Task. Controlled Study on 8-13 Years Childs
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    October 2015
    Overall Recruitment Status
    Completed
    Study Start Date
    February 2014 (undefined)
    Primary Completion Date
    February 2014 (Actual)
    Study Completion Date
    August 2014 (Actual)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Sponsor
    Name of the Sponsor
    Centre Hospitalier Universitaire de Nice

    4. Oversight

    Data Monitoring Committee
    No

    5. Study Description

    Brief Summary
    Introduction: Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors. There's also deficits in social cognition. When having a face-to-face conversation, a listener not only hears what a speaker is saying, but also sees the articulatory gestures that accompany those sounds. Speech signals needs then a multisensory processing. Impairments in multisensory perceptual binding may be particularly relevant in ASD, given that hallmark features of the disorder include difficulties in speech, communication, and social interactions. Objectives: The investigator suggest that atypical multisensory processing in ASD may have an impact on speech perception and social processing. Aims: Methods: This pilot study measures free recall scores in 3 lists of words presentation after 30 minutes. In the first condition (CI) words are only listening. In the second condition (CII) words are associated with a picture of a mans face. In the third condition (CIII) words are associated with a video of a man speaking. Three lists are homogeneous form words characteristics (lexical frequency, emotional valence norm, imageability). Participants were 7- to 13-year-olds typically developing children (TD) (N = 19) and ASD children (N = 19). The investigator would create some new tools for exploring the treatment of a social information. These tools should be the closest of a ecological social interaction.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Autism

    7. Study Design

    Primary Purpose
    Basic Science
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Masking
    None (Open Label)
    Allocation
    Non-Randomized
    Enrollment
    38 (Actual)

    8. Arms, Groups, and Interventions

    Arm Title
    autistic patient
    Arm Type
    Other
    Arm Description
    patient with autistic trouble
    Arm Title
    healthy volunteers
    Arm Type
    Other
    Arm Description
    healthy volunteers
    Intervention Type
    Other
    Intervention Name(s)
    memory test
    Primary Outcome Measure Information:
    Title
    rate of reminder after 30 minutes between the group autistic and the group witness( %)
    Description
    Comparison between the group autistic and the group witness of the difference enter the rate of reminder(abseiling) in 30 minutes of the words proposed in video and audio sequences.
    Time Frame
    30 minutes
    Secondary Outcome Measure Information:
    Title
    Difference of the scores of reminders words (%)
    Description
    Difference of the scores of reminders between the both group, immediately after procedure and 30 minutes after procedure
    Time Frame
    30 minutes

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    7 Years
    Maximum Age & Unit of Time
    13 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: Boy or girl, 7 - 13 years, Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS, Upper total IQ or equal to 50, examination dating less than year before the inclusion, French-speaking children, Signature of the informed consent by the parents(relatives) and the child, Membership to the Social Security. Exclusion Criteria: Genetic, neurological or neurosensory pathologies, Diagnosis of intrusive disorder(confusion) of the not specified development: TED our, The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.

    12. IPD Sharing Statement

    Learn more about this trial

    Multisensorial Information's Treatment in Autism Spectrum Disorder

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